Search Results - "Kaplan, Henry"

Role of epithelial–mesenchymal transition in proliferative vitreoretinopathy by Tamiya, Shigeo, Kaplan, Henry J.

“…Proliferative vitreoretinopathy (PVR) is a potentially blinding fibrotic complication. It is caused by the formation and contraction of epiretinal membranes…”
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Differential presentation and survival of de novo and recurrent metastatic breast cancer over time: 1990–2010 by Malmgren, Judith A., Mayer, Musa, Atwood, Mary K., Kaplan, Henry G.

“…Background Differences in de novo (dnMBC) and recurrent metastatic breast cancer (rMBC) presentation and survival over time have not been adequately described…”
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Continued proportional age shift of confirmed positive COVID-19 incidence over time to children and young adults: Washington State March-August 2020 by Malmgren, Judith, Guo, Boya, Kaplan, Henry G

“…As the coronavirus (COVID-19) epidemic passed initial infection peak in Washington State, phased re-opening lifted stay-at-home orders and restrictions leading…”
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Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact by Tamiya, Shigeo, Liu, LanHsin, Kaplan, Henry J

“…Molecular mechanisms that initiate epithelial-mesenchymal transition (EMT) involved in ocular fibrotic complications remain elusive. Studies were conducted to…”
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Prolonged Survival of NUT Midline Carcinoma and Current Approaches to Treatment by Kaplan, Henry G, Subramaniam, Somasundaram, Vallières, Eric, Barnett, Todd

“…Abstract NUT midline carcinoma is a rare malignancy most commonly seen in adolescents and young adults. The disease presents most often in the lung or head and…”
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Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia by Wu, Jun, Chen, Nu, Liu, Yongqing, Godlewski, Grzegorz, Kaplan, Henry J, Shrader, Sarah H, Song, Zhao-Hui, Shao, Hui

“…Cannabidiol (CBD) exhibits anti-inflammatory and neuroprotective properties and is suggested to be effective in the pre-clinical and clinical treatment of…”
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Persistence of patient‐detected breast cancer over time: 1990–2019 by Malmgren, Judith A., Atwood, Mary K., Kaplan, Henry G.

“…Background The continued presentation of patient‐detected breast cancer (BC) and associated characteristics over time is understudied. Methods In a large…”
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Timing Effect of Adenosine-Directed Immunomodulation on Mouse Experimental Autoimmune Uveitis by Ko, Minhee K, Shao, Hui, Kaplan, Henry J, Sun, Deming

“…Adenosine is an important regulatory molecule of the immune response. We have previously reported that treatment of experimental autoimmune uveitis (EAU)-prone…”
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Examination of a paradox: recurrent metastatic breast cancer incidence decline without improved distant disease survival: 1990–2011 by Malmgren, Judith, Hurlbert, Marc, Atwood, Mary, Kaplan, Henry G.

“…Purpose Distant relapse metastatic breast cancer (rMBC) incidence and survival are vital measures of breast cancer diagnosis and treatment progress over time…”
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Metastatic breast cancer survival improvement restricted by regional disparity: Surveillance, Epidemiology, and End Results and institutional analysis: 1990 to 2011 by Malmgren, Judith A., Calip, Gregory S., Atwood, Mary K., Mayer, Musa, Kaplan, Henry G.

“…Background The extent of breast cancer outcome disparity can be measured by comparing Surveillance, Epidemiology, and End Results (SEER) breast cancer‐specific…”
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γδ T Cells Activated in Different Inflammatory Environments Are Functionally Distinct by Sun, Deming, Chan, Nymph, Shao, Hui, Born, Willi K, Kaplan, Henry J

“…γδ T cells are important immunoregulatory cells in experimental autoimmune uveitis (EAU), and the activation status of γδ T cells determines their…”
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Damage-associated Molecular Patterns in Clinical and Animal Models of Uveitis by Kaplan, Henry J., Sun, Deming, Shao, Hui

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Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa by Wang, Wei, Lee, Sang Joon, Scott, Patrick A., Lu, Xiaoqin, Emery, Douglas, Liu, Yongqin, Ezashi, Toshihiko, Roberts, Michael R., Ross, Jason W., Kaplan, Henry J., Dean, Douglas C.

“…Most retinitis pigmentosa (RP) mutations arise in rod photoreceptor genes, leading to diminished peripheral and nighttime vision. Using a pig model of…”
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Exosomes from Retinal Astrocytes Contain Antiangiogenic Components That Inhibit Laser-induced Choroidal Neovascularization by Hajrasouliha, Amir Reza, Jiang, Guomin, Lu, Qingxian, Lu, Huayi, Kaplan, Henry J., Zhang, Huang-Ge, Shao, Hui

“…Exosomes released from different types of host cells have different biological effects. We report that exosomes released from retinal astroglial cells (RACs)…”
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An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation by Chen, Mingjiazi, Liang, Dongchun, Zuo, Aijun, Shao, Hui, Kaplan, Henry J, Sun, Deming

“…We have recently reported that, although adenosine receptor (AR) agonists have a suppressive effect on Th1 autoreactive T cells, their effect on Th17…”
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Role of Complement in the Onset of Age-Related Macular Degeneration by Piri, Niloofar, Kaplan, Henry J

“…Age-related macular degeneration (AMD) is a progressive degenerative disease of the central retina and the leading cause of severe loss of central vision in…”
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Vaccination with circulating exosomes in autoimmune uveitis prevents recurrent intraocular inflammation by Jiang, Guomin, Yun, Juan, Kaplan, Henry J., Zhao, Yuan, Sun, Deming, Shao, Hui

“…Background Exosomes participate in intercellular communication and act as important molecular vehicles in the regulation of numerous physiological and…”
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CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis by Liang, Dongchun, Zuo, Aijun, Zhao, Ronglan, Shao, Hui, Born, Willi K, O'Brien, Rebecca L, Kaplan, Henry J, Sun, Deming

“…γδ T cells can either enhance or inhibit an adaptive immune response, but the mechanisms involved are not fully understood. Given that CD73 is the main enzyme…”
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Trastuzumab therapy duration in HER2-positive de novo metastatic breast cancer: 1999–2018 by Kaplan, Henry G., Malmgren, Judith A., Guo, Boya, Atwood, Mary K.

“…Purpose The optimal duration of first-line trastuzumab (T) treatment for de novo stage IV HER2-positive metastatic breast cancer (MBC) patients after complete…”
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Augmented Th17-stimulating activity of BMDCs as a result of reciprocal interaction between γδ and dendritic cells by Sun, Deming, Ko, Minhee K., Shao, Hui, Kaplan, Henry J.

“…•Reciprocal interactions between mouse γδ T cells and dendritic cells (DCs) played a major role in γδ regulation of Th17 responses.•Mouse bone marrow-derived…”
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