Search Results - "Kaplan, D.L"

Accelerated wound healing in a diabetic rat model using decellularized dermal matrix and human umbilical cord perivascular cells by Milan, P. Brouki, Lotfibakhshaiesh, N., Joghataie, M.T., Ai, J., Pazouki, A., Kaplan, D.L., Kargozar, S., Amini, N., Hamblin, M.R., Mozafari, M., Samadikuchaksaraei, A.

“…[Display omitted] There is an unmet clinical need for novel wound healing strategies to treat full thickness skin defects, especially in diabetic patients. We…”
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Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing by Schneider, A., Wang, X.Y., Kaplan, D.L., Garlick, J.A., Egles, C.

“…Materials able to deliver topically bioactive molecules represent a new generation of biomaterials. In this article, we describe the use of silk mats, made of…”
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Carbonic anhydrase generates a pH gradient in Bombyx mori silk glands by Domigan, L.J., Andersson, M., Alberti, K.A., Chesler, M., Xu, Q., Johansson, J., Rising, A., Kaplan, D.L.

“…Silk is a protein of interest to both biological and industrial sciences. The silkworm, Bombyx mori, forms this protein into strong threads starting from…”
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Matrigel-Free Laminin–Entactin Matrix to Induce Human Renal Proximal Tubule Structure Formation In Vitro by Adelfio, M, Szymkowiak, S, Kaplan, D.L

“…A successful in vitro tissue model must recapitulate the native tissue features while also being reproducible. Currently, Matrigel is the principal biomaterial…”
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Aligned silk-based 3-D architectures for contact guidance in tissue engineering by Oliveira, A.L., Sun, L., Kim, H.J., Hu, X., Rice, W., Kluge, J., Reis, R.L., Kaplan, D.L.

“…An important challenge in the biomaterials field is to mimic the structure of functional tissues via cell and extracellular matrix (ECM) alignment and…”
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Silk fibroin as an organic polymer for controlled drug delivery by Hofmann, S., Wong Po Foo, C.T., Rossetti, F., Textor, M., Vunjak-Novakovic, G., Kaplan, D.L., Merkle, H.P., Meinel, L.

“…The pharmaceutical utility of silk fibroin (SF) materials for drug delivery was investigated. SF films were prepared from aqueous solutions of the fibroin…”
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Effect of self-assembled nanofibrous silk/polycaprolactone layer on the osteoconductivity and mechanical properties of biphasic calcium phosphate scaffolds by Roohani-Esfahani, S.I., Lu, Z.F., Li, J.J., Ellis-Behnke, R., Kaplan, D.L., Zreiqat, H.

“…We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite…”
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Silk based biomaterials to heal critical sized femur defects by Meinel, L., Betz, O., Fajardo, R., Hofmann, S., Nazarian, A., Cory, E., Hilbe, M., McCool, J., Langer, R., Vunjak-Novakovic, G., Merkle, H.P., Rechenberg, B., Kaplan, D.L., Kirker-Head, C.

“…Bone auto- and allografts have inherent drawbacks, therefore the treatment of non-unions and critical size defects in load bearing long bones would benefit…”
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Role of pH and charge on silk protein assembly in insects and spiders by Foo, C. Wong Po, Bini, E., Hensman, J., Knight, D.P., Lewis, R.V., Kaplan, D.L.

“…Silk fibers possess impressive mechanical properties, dependant, in part, on the crystalline β-sheets silk II conformation. The transition to silk II from…”
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Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytes by Rainbow, R.S, Kwon, H, Foote, A.T, Preda, R.C, Kaplan, D.L, Zeng, L

“…Summary Objective Pro-inflammatory cytokines play an important role in inducing cartilage degradation during osteoarthritis pathogenesis. Muscle is a tissue…”
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Biosynthesis of emulsan biopolymers from agro-based feedstocks by Panilaitis, B, Castro, G.R, Solaiman, D, Kaplan, D.L

“…The need for biocompatible, biodegradable, and versatile biopolymers permeates many fields including environmental and food technology. The goal of the study…”
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Human bone marrow-derived mesenchymal stem cell homing to orthotopic breast cancer tumors and promotion of bone metastasis by Reagan, M.R, Goldstein, R, Rosenblatt, M, Kaplan, D.L

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456 PUTATIVE 3D HUMAN TISSUE MODEL FOR OSTEOARTHRITIS by Sun, L, Kaplan, D.L

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Biocatalytic Route to Ascorbic Acid-Modified Polymers for Free-Radical Scavenging by Singh, A., Kaplan, D.L.

“…Ascorbic acid functionalized polymers (see Figure) for free radical scavenging have been synthesized via a two step biocatalytic route. The ascorbic acid…”
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Corrigendum to “Silk based biomaterials to heal critical sized femur defects” [Bone 39 (2006) 922–931] by Meinel, L, Betz, O, Fajardo, R, Hofmann, S, Nazarian, A, Cory, E, Hilbe, M, McCool, J, Langer, R, Vunjak-Novakovic, G, Merkle, H.P, Rechenberg, B, Kaplan, D.L, Kirker-Head, C

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The host galaxy of a fast radio burst by Keane, E. F., Johnston, S., Bhandari, S., Barr, E., Bhat, N. D. R., Burgay, M., Caleb, M., Flynn, C., Jameson, A., Kramer, M., Petroff, E., Possenti, A., van Straten, W., Bailes, M., Burke-Spolaor, S., Eatough, R. P., Stappers, B. W., Totani, T., Honma, M., Furusawa, H., Hattori, T., Morokuma, T., Niino, Y., Sugai, H., Terai, T., Tominaga, N., Yamasaki, S., Yasuda, N., Allen, R., Cooke, J., Jencson, J., Kasliwal, M. M., Kaplan, D. L., Tingay, S. J., Williams, A., Wayth, R., Chandra, P., Perrodin, D., Berezina, M., Mickaliger, M., Bassa, C.

“…Observations of a six-day-long radio transient following a fast radio burst have yielded the host galaxy’s redshift, which, combined with the dispersion…”
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3D multi-channel bi-functionalized silk electrospun conduits for peripheral nerve regeneration by Dinis, T.M., Elia, R., Vidal, G., Dermigny, Q., Denoeud, C., Kaplan, D.L., Egles, C., Marin, F.

“…Despite technological advances over the past 25 years, a complete recovery from peripheral nerve injuries remains unsatisfactory today. The autograft is still…”
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A millisecond pulsar in a stellar triple system by Ransom, S. M., Stairs, I. H., Archibald, A. M., Hessels, J. W. T., Kaplan, D. L., van Kerkwijk, M. H., Boyles, J., Deller, A. T., Chatterjee, S., Schechtman-Rook, A., Berndsen, A., Lynch, R. S., Lorimer, D. R., Karako-Argaman, C., Kaspi, V. M., Kondratiev, V. I., McLaughlin, M. A., van Leeuwen, J., Rosen, R., Roberts, M. S. E., Stovall, K.

“…Precision timing and multiwavelength observations of a millisecond pulsar in a triple system show that the gravitational interactions between the bodies are…”
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Controllable transition of silk fibroin nanostructures: An insight into in vitro silk self-assembly process by Bai, S., Liu, S., Zhang, C., Xu, W., Lu, Q., Han, H., Kaplan, D.L, Zhu, H.

“…Silk fiber is one of the strongest and toughest biological materials with hierarchical structures, where nanofibril with size <20nm is a critical factor in…”
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Mechanism of silk processing in insects and spiders by Kaplan, David L, Jin, Hyoung-Joon

“…Silk spinning by insects and spiders leads to the formation of fibres that exhibit high strength and toughness. The lack of understanding of the protein…”
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