Search Results - "Kapke, Gordon"

Considerations in the development of circulating tumor cell technology for clinical use by Parkinson, David R, Dracopoli, Nicholas, Petty, Brenda Gumbs, Compton, Carolyn, Cristofanilli, Massimo, Deisseroth, Albert, Hayes, Daniel F, Kapke, Gordon, Kumar, Prasanna, Lee, Jerry Sh, Liu, Minetta C, McCormack, Robert, Mikulski, Stanislaw, Nagahara, Larry, Pantel, Klaus, Pearson-White, Sonia, Punnoose, Elizabeth A, Roadcap, Lori T, Schade, Andrew E, Scher, Howard I, Sigman, Caroline C, Kelloff, Gary J

“…This manuscript summarizes current thinking on the value and promise of evolving circulating tumor cell (CTC) technologies for cancer patient diagnosis,…”
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Assay validation for KIM-1: human urinary renal dysfunction biomarker by Chaturvedi, Shalini, Farmer, Takeisha, Kapke, Gordon F

“…Urinary kidney injury molecule (KIM-1) is a sensitive quantitative biomarker for early detection of kidney tubular injury. The objective of the present work…”
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Adaptive Bayesian Analysis of Serum Creatinine as a Marker for Drug-Induced Renal Impairment in an Early-Phase Clinical Trial by SOTTAS, Pierre-Edouard, KAPKE, Gordon F, LEROUX, Jean-Marc

“…A concern with using creatinine for the identification of drug-induced renal impairment is that small changes in serum creatinine (SCr) that frequently are…”
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Adaptive Bayesian approach to clinical trial renal impairment biomarker signal from urea and creatinine by Sottas, Pierre-Edouard, Kapke, Gordon F, Leroux, Jean-Marc

“…A major concern with the identification of renal toxicity using the traditional biomarkers, urea and creatinine, is that toxicity signal definitions are not…”
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Patient-specific measures of a biomarker for the generation of individual reference intervals: hemoglobin as example by Sottas, Pierre-Edouard, Kapke, Gordon F, Vesterqvist, Ole, Leroux, Jean-Marc

“…Although hemoglobin concentration measurement is among the most commonly performed blood tests, the description of global population parameters, heterogeneous…”
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Additional investigations fail to alter the diagnosis of irritable bowel syndrome in subjects fulfilling the Rome criteria by Hamm, Lynne R, Sorrells, Susan C, Harding, Jacqueline P, Northcutt, Allison R, Heath, Amy T, Kapke, Gordon F, Hunt, Christine M, Mangel, Allen W

“…Irritable bowel syndrome (IBS) is diagnosed by the presence of a constellation of symptoms fulfilling the Manning or Rome Criteria, after exclusion of organic…”
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Local Laboratory Reference Intervals in Clinical Trials by Dijkman, Jaap H. M., Fraser, Callum G., Treasure, F. Peter, Kapke, Gordon F.

“…Assessment of whether laboratory results in clinical studies are abnormal relies heavily on the laboratory upper or lower reference limits. While central…”
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Assessment of Hepatitis B Virus DNA Stability in Serum by the Chiron Quantiplex Branched-DNA Assay by KRAJDEN, M, COMANOR, L, RIFKIN, O, GRIGORIEW, A, MINOR, J. M, KAPKE, G. F

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Additional investigations fail to alter the diagnosis of irritable bowel syndrome in subjects fulfilling the Rome criteria by Hamm, Lynne R, Sorrells, Susan C, Harding, Jacqueline P, Northcutt, Allison R, Heath, Amy T, Kapke, Gordon F, Hunt, Christine M, Mangel, Allen W

“…OBJECTIVE: Irritable bowel syndrome (IBS) is diagnosed by the presence of a constellation of symptoms fulfilling the Manning or Rome Criteria, after exclusion…”
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PURIFICATION AND PROPERTIES OF SHEEP LIVER SERINE-THREONINE DEHYDRATASE by KAPKE, GORDON FRANKLIN

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Deamination of the microbial toxin trans L-2-amino-4-methoxy-3-butenoic acid and its parent vinylglycine by sheep liver serine-threonine dehydratase by Kapke, G, Davis, L

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Stereochemistry of the reaction of sheep liver threonine dehydratase. A nuclear magnetic resonance and optical rotatory dispersion study of its reaction pathway and products by Kapke, Gordon, Davis, Leodis

“…Products, substrates, and inhibitors of the threonine dehydratase from sheep liver (EC 4.2.1.16) have been investigated by proton nuclear magnetic resonance…”
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Sheep liver serine-threonine dehydratase. I. Purification and evidence for covalently linked α-ketobutyrate as its cofactor by Kapke, Gordon, Davis, Leodis

“…L-Serine-threonine dehydratase (EC 4.2.1.16) from sheep liver has been obtained as a highly purified preparation as shown by ultracentrifuge studies and…”
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Hepatic mitochondrial cholesterol hydroxylase activity--a cytochrome P-450-catalyzed mono-oxygenation refractory to cobaltous chloride by Kapke, G F, Baron, J

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Alterations in the contents of cytochrome P-450 and adrenal ferredoxin in adrenals of spontaneously hypertensive rats by Hartle, D K, Kapke, G F, Baron, J

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Immunohistochemical localization of adrenal ferredoxin in bovine adrenal cortex by Redick, J A, Kapke, G F, Van Orden, 3rd, L S, Baron, J

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