Search Results - "Kapin, Michael A"

Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress by Collier, Robert J, Patel, Yamini, Martin, Elizabeth A, Dembinska, Olga, Hellberg, Mark, Krueger, D Scott, Kapin, Michael A, Romano, Carmelo

“…5-HT(1A) agonists are neuroprotective in CNS injury models. The authors evaluated the efficacy of 5-HT(1A) agonists to protect the retina from severe blue…”
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CEP biomarkers as potential tools for monitoring therapeutics by Renganathan, Kutralanathan, Gu, Jiayin, Rayborn, Mary E, Crabb, John S, Salomon, Robert G, Collier, Robert J, Kapin, Michael A, Romano, Carmelo, Hollyfield, Joe G, Crabb, John W

“…Carboxyethylpyrrole (CEP) adducts are oxidative modifications derived from docosahexaenoate-containing lipids that are elevated in ocular tissues and plasma in…”
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Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye by Chastain, James E., Sanders, Mark E., Curtis, Michael A., Chemuturi, Nagendra V., Gadd, Martha E., Kapin, Michael A., Markwardt, Kerry L., Dahlin, David C.

“…Nepafenac ophthalmic suspensions, 0.1% (NEVANAC®) and 0.3% (ILEVRO™), are topical nonsteroidal anti-inflammatory drug (NSAID) products approved in the United…”
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Levobetaxolol-induced Up-regulation of Retinal bFGF and CNTF mRNAs and Preservation of Retinal Function Against a Photic-induced Retinopathy by Agarwal, Neeraj, Martin, Elizabeth, Krishnamoorthy, Raghu R., Landers, Robert, Wen, Rong, Krueger, Scott, Kapin, Michael A., Collier, Robert J.

“…Betaxolol (racemic), a β-adrenoceptor antagonist that is used to lower intraocular pressure in the treatment of glaucoma, has been shown to protect inner…”
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Eliprodil, a non-competitive, NR2B-selective NMDA antagonist, protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage by Reyes, Magali, Reyes, Ayesha, Opitz, Thoralf, Kapin, Michael A, K. Stanton, Patric

“…The N-methyl- d-aspartate (NMDA) subtype of glutamate receptor is one pathway through which excessive influx of calcium has been suggested to trigger…”
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Neuroprotective effects of eliprodil in retinal excitotoxicity and ischemia by Kapin, MA, Doshi, R, Scatton, B, DeSantis, LM, Chandler, ML

“…To evaluate whether eliprodil (SL82.0715), a NR2B-selective N-methyl-D-aspartate (NMDA) antagonist, is protective of retina subjected to an excitotoxic or…”
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Protection by eliprodil against excitotoxicity in cultured rat retinal ganglion cells by PANG, I.-H, WEXLER, E. M, NAWY, S, DESANTIS, L, KAPIN, M. A

“…To test whether eliprodil (SL 82.0715), a unique antagonist for the N-methyl-D-aspartate (NMDA) receptor, is protective in the glutamate-induced cytotoxicity…”
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Developing neuroprotective drugs for glaucoma no easy task by Kapin, Michael A

“…Unquestionably, the successful development of a neuroprotective drug for glaucoma would be an achievement of the highest order. However, this achievement does…”
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Developing neuroprotective drugs for glaucoma no easy task: progress made in understanding etiology of the disease, but various obstacles need to be overcome by Kapin, Michael A

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