Search Results - "Kapembwa, Moses"

PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection by Pollock, Katrina M, Montamat-Sicotte, Damien J, Grass, Lisa, Cooke, Graham S, Kapembwa, Moses S, Kon, Onn M, Sampson, Robert D, Taylor, Graham P, Lalvani, Ajit

“…HIV co-infection is an important risk factor for tuberculosis (TB) providing a powerful model in which to dissect out defective, protective and dysfunctional…”
Get full text

T-Cell Immunophenotyping Distinguishes Active From Latent Tuberculosis by Pollock, Katrina M., Whitworth, Hilary S., Montamat-Sicotte, Damien J., Grass, Lisa, Cooke, Graham S., Kapembwa, Moses S., Kon, Onn M., Sampson, Robert D., Taylor, Graham P., Lalvani, Ajit

“…Background. Changes in the phenotype and function of Mycobacterium tuberculosis (M. tuberculosis)-specific CD4⁺ and CD8⁺ T-cell subsets in response to stage of…”
Get full text

HIV enteropathy and 'Slim disease': Historical and current perspectives by Kapembwa, Moses Silungwe, Batman, Philip Anthony, Fleming, Simon Charles, Griffin, George Edward

“…Chronic diarrhoea and severe wasting associated with HIV infection were first described in East African patients as slim disease (SD) in 1985. The main…”
Get full text

HIV enteropathy: HAART reduces HIV-induced stem cell hyperproliferation and crypt hypertrophy to normal in jejunal mucosa by Batman, Philip A, Kapembwa, Moses S, Belmonte, Liliana, Tudor, Gregory, Kotler, Donald P, Potten, Christopher S, Booth, Catherine, Cahn, Pedro, Griffin, George E

“…To analyse the structural and kinetic response of small intestinal crypt epithelial cells including stem cells to highly active antiretroviral therapy (HAART)…”
Get more information

Characteristics of Autoimmune Thyroid Disease Occurring as a Late Complication of Immune Reconstitution in Patients With Advanced Human Immunodeficiency Virus (HIV) Disease by Chen, Fabian, Day, Sara L., Metcalfe, Russell A., Sethi, Gulshan, Kapembwa, Moses S., Brook, M. Gary, Churchill, Duncan, de Ruiter, Annemiek, Robinson, Stephen, Lacey, Charles J., Weetman, Anthony P.

“…Experimental evidence from animal models has provided a framework for our current understanding of autoimmune disease pathogenesis and supports the importance…”
Get full text

Chemokine Receptor Expression on Mucosal Dendritic Cells from the Endocervix of Healthy Women by Prakash, Manyu, Kapembwa, Moses S., Gotch, Frances, Patterson, Steve

“…Dendritic cells (DCs) may be an initial target of human immunodeficiency virus (HIV) during heterosexual transmission. An analysis of DCs in the…”
Get full text

HIV enteropathy : crypt stem and transit cell hyperproliferation induces villous atrophy in HIV /Microsporidia -infected jejunal mucosa by BATMAN, Philip A, KOTLER, Donald P, KAPEMBWA, Moses S, BOOTH, Dawn, POTTEN, Christopher S, ORENSTEIN, Jan M, SCALLY, Andrew J, GRITTIN, George E

“…The study aim was to analyse the kinetics of stem and transit cells in the crypts of jejunal mucosa infected with HIV and Microsporidia. The size of villi,…”
Get full text

Comparison of screening strategies to improve the diagnosis of latent tuberculosis infection in the HIV-positive population: a cohort study by Pollock, Katrina M, Tam, Herman, Grass, Lisa, Bowes, Sharleen, Cooke, Graham S, Pareek, Manish, Montamat-Sicotte, Damien, Kapembwa, Moses, Taylor, Graham P, Lalvani, Ajit

“…BackgroundHIV is the most important risk factor for progression of latent tuberculosis infection (LTBI) to active tuberculosis (TB). Detection and treatment of…”
Get full text

Hormonal Upregulation of CCR5 Expression on T lymphocytes as a Possible Mechanism for Increased HIV-1 Risk by Prakash, Manyu, Patterson, Steve, Kapembwa, Moses S

Get full text

Differences in antigen‐specific CD4+ responses to opportunistic infections in HIV infection by Pollock, Katrina M., Montamat‐Sicotte, Damien J., Cooke, Graham S., Kapembwa, Moses S., Kon, Onn M., Grass, Lisa, Sampson, Robert D., Taylor, Graham P., Lalvani, Ajit

“…HIV‐infected individuals with severe immunodeficiency are at risk of opportunistic infection (OI). Tuberculosis (TB) may occur without substantial immune…”
Get full text

Oral contraceptive use induces upregulation of the CCR5 chemokine receptor on CD4 + T cells in the cervical epithelium of healthy women by Prakash, Manyu, Kapembwa, Moses S, Gotch, Frances, Patterson, Steven

“…Heterosexual transmission of human immunodeficiency virus type I (HIV-1) is the predominant mode of infection worldwide. Increased risk of HIV-1 transmission…”
Get full text

Recruitment of CD4+ T lymphocytes and macrophages into the cervical epithelium of women after coitus by Prakash, Manyu, Patterson, Steven, Gotch, Frances, Kapembwa, Moses S.

“…Objective: T lymphocytes and macrophages are considered essential components of the immune response. Many factors are known to influence the presence and…”
Get full text

Ex vivo analysis of HIV‐1 co‐receptors at the endocervical mucosa of women using oral contraceptives by Prakash, Manyu, Patterson, Steve, Gotch, Frances, Kapembwa, Moses S.

“…Combined oral contraceptives may alter the microenvironment of the female genital tract and, thus, influence susceptibility of endocervical cells to HIV‐1…”
Get full text

Evaluation of the cervical cytobrush sampling technique for the preparation of CD45+ mononuclear cells from the human cervix by Prakash, Manyu, Patterson, Steve, Kapembwa, Moses S

“…A cytobrush technique developed to prepare mononuclear cells from the intraepithelial layer of the endocervix has been evaluated. Specimens yielded…”
Get full text

Granuloma annulare masquerading as molluscum contagiosum–like eruption in an HIV-positive African woman by Kapembwa, Moses S, Goolamali, Saleem K, Price, Ashley, Boyle, Susan

“…A 33-year-old African woman who was HIV positive and being treated with zidovudine and zalcitabine presented with a 4-week history of a generalized pruritic…”
Get full text

Letter to the editor: Are we missing pancreatic exocrine insufficiency in ‘at-risk’ groups? by Kapembwa, Moses Silungwe, Fleming, Simon Charles, Batman, Philip Anthony, Griffin, George Edward

Get full text

Letter to the editor: Are we missing pancreatic exocrine insufficiency in 'at-risk' groups? by Kapembwa, Moses Silungwe, Fleming, Simon Charles, Batman, Philip Anthony, Griffin, George Edward

“…The prevalence of EPI in PLWHIV reported in this paper compares favourably with our own experience in a study of 25 PLWHIV.2 Our seminal work demonstrating EPI…”
Get full text

Higher levels of activation markers and chemokine receptors on T lymphocytes in the cervix than peripheral blood of normal healthy women by Prakash, Manyu, Kapembwa, Moses S, Gotch, Frances, Patterson, Steven

“…Heterosexual transmission of human immunodeficiency virus (HIV-1) is the predominant mode of infection world-wide. To better understand sexual transmission of…”
Get full text

Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT) by Paton, Nicholas I., Stöhr, Wolfgang, Clarke, Amanda, Williams, Ian, Orkin, Chloe, Chen, Fabian, Winston, Alan, Gompels, Mark, Dunn, David T., Fisher, Martin, Clarke, Amanda, Hadley, Wendy, Stacey, David, Johnson, Margaret, Byrne, Pat, Williams, Ian, De Esteban, Nahum, Pellegrino, Pierre, Haddow, Lewis, Arenas-Pinto, Alejandro, Orkin, Chloe, Hand, James, De Souza, Carl, Murthen, Lisa, Chen, Fabian, Green, Elizabeth, Masterson, John, Lee, Vincent, Patel, Kamlesh, Howe, Rebecca, Winston, Alan, Mullaney, Scott, Gompels, Mark, Tamaklo, Rebecca, Fox, Julie, Teague, Alistair, Jendrulek, Isabelle, Tiraboschi, Juan Manuel, Wilkins, Ed, Clowes, Yvonne, Aderogba, Kazeem, DeBurgh-Thomas, Andrew, Reeves, Iain, Mguni, Sifiso, Spence, Pauline, Nkhoma, Nellie, Warwick, Zoe, Price, Suzanne, Herieka, Elbushra, Walker, James, Woodward, Ruth, Day, John, Hilton, Laura, Hay, Phillip, Mejewska, Wendy, Ong, Edmund, Martin, Karen, Dockrell, David, Ainsworth, Jonathan, Waters, Anele, Kegg, Stephen, McNamara, Sara, Taylor, Steve, Gilleran, Gerry, Gazzard, Brian, Allan, Sris, Sandhu, Rumun, O'Farrell, Nigel, Quaid, Sheena, Kapembwa, Moses, Minton, Jane, Palfreeman, Adrian, Mashonganyika, Linda, Kakowa, Memory, O'Connell, Rebecca, Tanawa, Cheryl, Jebakumar, Sinna, McKernan, Sinead, Lacey, Charles, Douglas, Sarah, Russell-Sharpe, Sarah, Leen, Clifford, Obeyesekera, Sharmin, Williams, Shirley, David, Nelson, Paton, Nicholas, Scott, Karen, Beaumont, Emma, Fleck, Sue, Hall, Mark, Kummeling, Ischa, Owen-Powell, Ellen, van Hooff, Fionna, Cromerty, Ben, Mercey, Danielle, Fidler, Sarah, Babiker, Abdel, Peto, Tim, Lalloo, David, James, Robert

“…Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy switch strategy…”
Get full text

Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT)Research in context by Nicholas I. Paton, Wolfgang Stöhr, Alejandro Arenas-Pinto, Amanda Clarke, Ian Williams, Margaret Johnson, Chloe Orkin, Fabian Chen, Vincent Lee, Alan Winston, Mark Gompels, Julie Fox, Karen Sanders, David T. Dunn, Martin Fisher, Amanda Clarke, Wendy Hadley, David Stacey, Margaret Johnson, Pat Byrne, Ian Williams, Nahum De Esteban, Pierre Pellegrino, Lewis Haddow, Alejandro Arenas-Pinto, Chloe Orkin, James Hand, Carl De Souza, Lisa Murthen, Andrew Crawford-Jones, Fabian Chen, Ruth Wilson, Elizabeth Green, John Masterson, Vincent Lee, Kamlesh Patel, Rebecca Howe, Alan Winston, Scott Mullaney, Mark Gompels, Louise Jennings, Nicholas Beeching, Rebecca Tamaklo, Julie Fox, Alistair Teague, Isabelle Jendrulek, Juan Manuel Tiraboschi, Ed Wilkins, Yvonne Clowes, Andrew Thompson, Gary Brook, Manoj Trivedi, Kazeem Aderogba, Martin Jones, Andrew DeBurgh-Thomas, Liz Jones, Iain Reeves, Sifiso Mguni, David Chadwick, Pauline Spence, Nellie Nkhoma, Zoe Warwick, Suzanne Price, Sally Read, Elbushra Herieka, James Walker, Ruth Woodward, John Day, Laura Hilton, Veerakathy Harinda, Helen Blackman, Phillip Hay, Wendy Mejewska, Olanike Okolo, Edmund Ong, Karen Martin, Lee Munro, David Dockrell, Lynne Smart, Jonathan Ainsworth, Anele Waters, Stephen Kegg, Sara McNamara, Steve Taylor, Gerry Gilleran, Brian Gazzard, Jane Rowlands, Sris Allan, Rumun Sandhu, Nigel O'Farrell, Sheena Quaid, Fabiola Martin, Caroline Bennett, Moses Kapembwa, Jane Minton, James Calderwood, Frank Post, Lucy Campbell, Emily Wandolo, Adrian Palfreeman

“…Background: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy…”
Get full text