Search Results - "Kapedanovska, A"

Evaluation of the JAK2V617F mutational burden in patients with philadelphia chromosome negative myeloproliferative neoplasms: A single-center experience by Popova-Labachevska, M, Panovska-Stavridis, I, Eftimov, A, Kapedanovska, Nestorovska A, Cevreska, L, Ivanovski, M, Ridova, N, Trajkova, S, Dimovski, AJ

“…The identification of the JAK2V617F mutation in several distinct myeloproliferative neoplasms (MPNs) raised the question how one single mutation incites…”
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Influence of SLCO1B1 polymorphisms on atorvastatin efficacy and safety in Macedonian subjects by Mladenovska, K, Grapci, A Daka, Vavlukis, M, Kapedanovska, A, Eftimov, A, Geshkovska, N Matevska, Nebija, D, Dimovski, A J

“…Atorvastatin, as 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, is a widely prescribed medication for the treatment of dyslipidemia…”
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Effects of single nucleotide polymorphisms and haplotypes of the SLCO1B1 gene on the pharmacokinetic profile of atorvastatin in healthy Macedonian volunteers by Daka, A, Dimovski, A, Kapedanovska, A, Vavlukis, M, Eftimov, A, Labachevski, N, Jakjovski, K, Geshkovska, Matevska N, Nebija, D, Mladenovska, K

“…OATP1B1 is an influx transporter known to mediate the uptake of various endogenous compounds and xenobiotics. Several sequence variations have been discovered…”
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Characterization of the most common CYP2C9 and CYP2C19 allelic variants in the population from the Republic of Macedonia by Jakovski, K, Nestorovska, A Kapedanovska, Labacevski, N, Dimovski, A J

“…The aim of this study was to evaluate the most common CYP2C9 and CYP2C19 polymorphisms in the population of Macedonia and compare them with the global…”
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Pharmacoeconomic Evaluation of Sorafenib As First-Line Treatment for Advanced Hepatocellular Carcinoma by Naumovska, Z, Kapedanovska Nestorovska, A, Grozdanova, A, Suturkova, L, Dimovski, A, Sterjev, Z

“…OBJECTIVES: Sorafenib significantly improve the overall survival of patients with advanced hepatocellular carcinoma (HCC). Conducted research aimed to assess…”
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Cost –Effectiveness of Obinutuzumab As Frontline Treatment For Unfit Patients With Chronic Lymphocytic Leukemia In Republic of Macedonia by Kapedanovska Nestorovska, A, Sterjev, Z, Naumovska, Z, Grozdanova, A, Dimovski, A, Suturkova, L

“…OBJECTIVES: According to the results from the CLL-11 trial, obinutuzumab+ chlorambucil (G-Clb) is superior to rituximab+chlorambucil (R-Clb) leading to an 13.8…”
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Distribution of the Most Common Genetic Variants Associated with a Variable Drug Response in the Population of the Republic of Macedonia by Nestorovska, Kapedanovska A., Jakovski, K., Naumovska, Z., Bajro, Hiljadnikova M., Sterjev, Z., Eftimov, A., Geskovska, Matevska N., Suturkova, L., Dimitrovski, K., Labacevski, N., Dimovski, A. J.

“…Genetic variation in the regulation, expression and activity of genes coding for Phase I, Phase II drug metabolizing enzymes (DMEs) and drug targets, can be…”
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Frequencies of Single-Nucleotide Polymorphisms and Haplotypes of the SLCO1B1 Gene in Selected Populations of the Western Balkans by Daka Grapci, A., Dimovski, A. J., Kapedanovska, A., Vavlukis, M., Eftimov, A., Matevska Geshkovska, N., Labachevski, N., Jakjovski, K., Gorani, D., Kedev, S., Mladenovska, Kristina

“…As a membrane influx transporter, organic anion- transporting polypeptide 1B1 (OATP1B1) regulates the cellular uptake of a number of endogenous compounds and…”
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Treatment in Transplant Eligible Multiple Myeloma Patients in Macedonia: Development of Cost-Effectiveness Analysis by Qerimi, V, Kapedanovska-Nestorovska, A, Sterjev, Z, Genadieva-Stavric, S, Suturkova, L

“…OBJECTIVES: We developed a decision-analytic model to study the impact of the three induction regimens: Vincristine-Adriamycin-Dexarnethasone (VAD),…”
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Impact of biosimilar medicinal products in the EU pharmaceutical market by Grozdanova, A, Ancevska Netkovska, K, Sterjev, Z, Naumovska, Z, Kapedanovska Nestorovska, A, Suturkova, L.j

“…Even though the most important conditions for market uptake of biosimilars are driven by commercial factors, still, real clinical evidence, clear regulatory…”
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Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk of Colorectal Cancer in the Macedonian Population by Matevska, N, Josifovski, T, Kapedanovska, A, Sterjev, Z, Serafimoska, Z, Panovski, M, Jankulovski, N, Petrusevska, N, Angelovska, B, Petrusevska, G, Suturkova, L, Dimovski, A

“…Methylenetetrahydrofolate reductase (MTHFR) regulates the flow of folate groups between DNA synthesis and DNA methylation. A common C677T substitution…”
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Cyclin D1 G870A Variant is Associated with Increased Risk of Microsatellite Instability-Positive Colorectal Cancer in Young Male Patients by Josifovski, T, Matevska, N, Hiljadnikova-Bajro, M, Sterjev, Z, Kapedanovska, A, Serafimoska, Z, Despotovska, S, Petrusevska, N, Panovski, M, Suturkova, L, Dimovski, A

“…Cyclin D1 (CCND1) is a cell cycle regulatory protein, which is often over expressed in human tumors and is associated with cell proliferation and poor…”
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The Effects of the New Methodology Application on the Method of Pricing of Drugs—The Case of the Republic of Macedonia by Zareski, Rubin, Kapedanovska Nestorovska, A., Grozdanova, A., Dimitrova, B., Suturkova, L.J., Sterjev, Z.

“…Background: The introduction of a new methodology for the pricing of drugs by the Agency of Medicines of the Republic of Macedonia for the period 2012 to 2015…”
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P6412The AKR1D136 (rs1872930) allelic variant is independently associated with adverse cardiac events during Clopidogrel treatment by Ugurov, P, Kapedanovska-Nestorovska, A, Rosalia, R A, Dimovski, A, Mitrev, Z K

“…Abstract Background The treatment of acute coronary syndrome (ACS) includes dual antiplatelet therapy (DAPT) comprising of aspirin and a P2Y12 inhibitor;…”
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PCN89 - COST –EFFECTIVENESS ANALYSIS OF PERTUZUMAB AS FIRST LINE NEOADJUVANT TREATMENT OPTION FOR PATIENTS HER2 + BREAST CANCER IN REPUBLIC OF MACEDONIA by Kapedanovska Nestorovska, A., Sterjev, Z., Naumovska, Z., Dimovski, A., Grozdanova, A., Suturkova, L.

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PCN128 - Treatment in Transplant Eligible Multiple Myeloma Patients in Macedonia: Development of Cost-Effectiveness Analysis by Qerimi, V, Kapedanovska-Nestorovska, A, Sterjev, Z, Genadieva-Stavric, S, Suturkova, L

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PRM34 - Cost –Effectiveness of Obinutuzumab As Frontline Treatment For Unfit Patients With Chronic Lymphocytic Leukemia In Republic of Macedonia by Kapedanovska Nestorovska, A, Sterjev, Z, Naumovska, Z, Grozdanova, A, Dimovski, A, Suturkova, L

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PRM36 - Pharmacoeconomic Evaluation of Sorafenib As First-Line Treatment for Advanced Hepatocellular Carcinoma by Naumovska, Z, Kapedanovska Nestorovska, A, Grozdanova, A, Suturkova, L, Dimovski, A, Sterjev, Z

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Influence of MSI and 18q LOH markers on capecitabine adjuvant monotherapy in colon cancer patients by Matevska-Geshkovska, Nadica, Staninova-Stojovska, Marija, Kapedanovska-Nestorovska, Aleksandra, Petrushevska-Angelovska, Natalija, Panovski, Milco, Grozdanovska, Biljana, Mitreski, Nenad, Dimovski, Aleksandar

“…The aim of this study was to evaluate whether pretreatment analysis of selected molecular markers can be used for the prediction of disease-free survival…”
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Cost-effectiveness analysis of treating transplant-eligible multiple myeloma patients in Macedonia by Qerimi, Vjollca, Nestorovska, Aleksandra Kapedanovska, Sterjev, Zoran, Genadieva-Stavric, Sonja, Suturkova, Ljubica

“…A decision-analytic model was developed to study the impact of induction regimens vincristine, adriamycin, dexamethasone (VAD); thalidomide, dexamethasone…”
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