Search Results - "Kapadia, Geeta"

Structure of Phosphorylated Enzyme I, the Phosphoenolpyruvate: Sugar Phosphotransferase System Sugar Translocation Signal Protein by Teplyakov, Alexey, Lim, Kap, Zhu, Peng-Peng, Kapadia, Geeta, Chen, Celia C. H., Schwartz, Jennifer, Howard, Andrew, Reddy, Prasad T., Peterkofsky, Alan, Herzberg, Osnat

“…Bacterial transport of many sugars, coupled to their phosphorylation, is carried out by the phosphoenolpyruvate (PEP):sugar phosphotransferase system and…”
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Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii by Pieper, Ursula, Kapadia, Geeta, Mevarech, Moshe, Herzberg, Osnat

“…Background: The proteins of halophilic archaea require high salt concentrations both for stability and for activity, whereas they denature at low ionic…”
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Investigation of the Catalytic Site within the ATP-Grasp Domain of Clostridium symbiosum Pyruvate Phosphate Dikinase by Ye, Dongmei, Wei, Min, McGuire, Marielena, Huang, Kui, Kapadia, Geeta, Herzberg, Osnat, Martin, Brian M., Dunaway-Mariano, Debra

“…Pyruvate phosphate dikinase (PPDK) catalyzes the interconversion of ATP, Pi, and pyruvate with AMP, PPi, and phosphoenolpyruvate (PEP) in three partial…”
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Structure of S-Lectin, a Developmentally Regulated Vertebrate β- Galactoside-Binding Protein by Liao, Der-Ing, Kapadia, Geeta, Ahmed, Hafiz, Vasta, Gerardo R., Herzberg, Osnat

“…The crystal structure of a 14-kDa bovine spleen S-lectin complexed with the disaccharide N-acetyllactosamine at 1.9-$\overset{circ}{Matrm A}$resolution reveals…”
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Digoxin metabolism in the elderly by Ewy, G A, Kapadia, G G, Yao, L, Lullin, M, Marcus, F I

“…Tritiated digoxin (0.5 mg) was given intravenously to five elderly men (mean age, 77 years) and nine young men (mean age, 27 years). The elderly were not in…”
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Role of the Ω-Loop in the Activity, Substrate Specificity, and Structure of Class A β-Lactamase by Banerjee, Soojay, Pieper, Ursula, Kapadia, Geeta, Pannell, Lewis K, Herzberg, Osnat

“…The structure of class A β-lactamases contains an Ω-loop associated with the active site, which carries a key catalytic residue, Glu166. A 16-residue Ω-loop…”
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Swiveling-Domain Mechanism for Enzymatic Phosphotransfer between Remote Reaction Sites by Herzberg, Osnat, Celia C. H. Chen, Kapadia, Geeta, McGuire, Marielena, Carroll, Lawrence J., Noh, Seong J., Dunaway-Mariano, Debra

“…The crystal structure of pyruvate phosphate dikinase, a histidyl multiphosphotransfer enzyme that synthesizes adenosine triphosphate, reveals a three-domain…”
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Structure of the Histidine-Containing Phosphocarrier Protein HPr from Bacillus subtilis at 2.0-Å Resolution by Herzberg, Osnat, Reddy, Prasad, Sutrina, Sarah, Saier, Milton H., Reizer, Jonathan, Kapadia, Geeta

“…The crystal structure of the histidine-containing phosphocarrier protein (HPr) of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) from Bacillus…”
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Location of the Phosphate Binding Site within Clostridium symbiosum Pyruvate Phosphate Dikinase by McGuire, Marielena, Huang, Kui, Kapadia, Geeta, Herzberg, Osnat, Dunaway-Mariano, Debra

“…Pyruvate phosphate dikinase (PPDK) catalyzes the interconversion of ATP, Pi, and pyruvate with AMP, PPi, and PEP in three partial reactions:  (1) E + ATP →…”
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Elimination of the Hydrolytic Water Molecule in a Class A β-Lactamase Mutant:  Crystal Structure and Kinetics by Zawadzke, Laura E, Chen, Celia C. H, Banerjee, Soojay, Li, Zhong, Wäsch, Susana, Kapadia, Geeta, Moult, John, Herzberg, Osnat

“…Two site-directed mutant enzymes of the class A β-lactamase from Staphylococcus aureus PC1 were produced with the goal of blocking the site that in the native…”
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Structure and Kinetics of the β-Lactamase Mutants S70A and K73H from Staphylococcus aureus PC1 by Chen, Celia C, Smith, Tom J, Kapadia, Geeta, Wäsch, Susana, Zawadzke, Laura E, Coulson, Andrew, Herzberg, Osnat

“…Two mutant β-lactamases from Staphylococcus aureus PC1 which probe key catalytic residues have been produced by site-directed mutagenesis. In the S70A enzyme,…”
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A promiscuous binding surface: crystal structure of the IIA domain of the glucose-specific permease from Mycoplasma capricolum by Huang, Kui, Kapadia, Geeta, Zhu, Peng-Peng, Peterkofsky, Alan, Herzberg, Osnat

“…Background: The phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a bacterial and mycoplasma system responsible for the uptake of some sugars,…”
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Structure of the IIA domain in the glucose permease of Bacillus subtilis at 2.2-Å resolution by LIAO, D.-I, KAPADIA, G, REDDY, P, SAIER, M. H, REIZER, J, HERZBERG, O

“…The crystal structure of the IIA domain of the glucose permease of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) from Bacillus subtilis has…”
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Structural basis for the inactivation of the P54 mutant of .beta.-lactamase from Staphylococcus aureus PC1 by Herzberg, Osnat, Kapadia, Geeta, Blanco, Bernardo, Smith, Tom S, Coulson, Andrew

“…The crystal structure of a mutant protein of a class A beta-lactamase from Staphylococcus aureus PC1, in which Asp179 is replaced by an asparagine (P54), has…”
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Structural evidence for the evolutionary divergence of mycoplasma from Gram-positive bacteria: the histidine-containing phosphocarrier protein by Pieper, Ursula, Kapadia, Geeta, Zhu, Peng-Peng, Peterkofsky, Alan, Herzberg, Osnat

“…Background: The three-dimensional structures of histidine-containing phosphocarrier protein (HPr), a member of the phosphoenolpyruvate:sugar phosphotransferase…”
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Structure of S-lectin, a developmentally regulated vertebrate (beta)-galactoside-binding protein by Liao, Der-Ing, Kapadia, Geeta, Ahmed, Hafiz, Vasta, Gerardo R, Herzberg, Osnat

“…A high-resolution crystal structure of the 14-kDa S-lectin from bovine spleen complexed with N-acetyllactosamine is reported. The carbohydrate site provides an…”
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Structure of the IIA domain of the glucose permease of Bacillus subtilis at 2.2-.ANG. resolution by Liao, Der Ing, Kapadia, Geeta, Reddy, Prasad, Saier, Milton H, Reizer, Jonathan, Herzberg, Osnat

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Crystallization of the IIA domain of the glucose permease of Bacillus subtilis by Kapadia, G, Chen, C C, Reddy, P, Saier, Jr, M H, Reizer, J, Herzberg, O

“…The IIA domain of the glucose permease of the phosphoenolpyruvate: sugar phosphotransferase system (PTS) from Bacillus subtilis has been crystallized. Crystals…”
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Crystallization of the Bacillus subtilis histidine-containing phosphocarrier protein HPr and of some of its site-directed mutants by Kapadia, G, Reizer, J, Sutrina, S L, Saier, Jr, M H, Reddy, P, Herzberg, O

“…The histidine-containing phosphocarrier protein (HPr) from Bacillus subtilis has been crystallized. Two of the site-directed mutants aimed at probing function…”
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Digitalization of the myocardium in the intact animal by direct coronary arterial drug administration by Roberge, Guy, Marcus, Frank I., Kapadia, Geeta G., Lown, Bernard

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