Search Results - "Kao, Linda"

APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease by Parsa, Afshin, Kao, W.H. Linda, Xie, Dawei, Astor, Brad C, Li, Man, Hsu, Chi-yuan, Feldman, Harold I, Parekh, Rulan S, Kusek, John W, Greene, Tom H, Fink, Jeffrey C, Anderson, Amanda H, Choi, Michael J, Wright, Jackson T, Lash, James P, Freedman, Barry I, Ojo, Akinlolu, Winkler, Cheryl A, Raj, Dominic S, Kopp, Jeffrey B, He, Jiang, Jensvold, Nancy G, Tao, Kaixiang, Lipkowitz, Michael S, Appel, Lawrence J

“…In this study, APOL1 variants were associated with an increased risk of progression of chronic kidney disease in black patients, as compared with white…”
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Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors by Yang, Qiong, Köttgen, Anna, Dehghan, Abbas, Smith, Albert V, Glazer, Nicole L, Chen, Ming-Huei, Chasman, Daniel I, Aspelund, Thor, Eiriksdottir, Gudny, Harris, Tamara B, Launer, Lenore, Nalls, Michael, Hernandez, Dena, Arking, Dan E, Boerwinkle, Eric, Grove, Megan L, Li, Man, Linda Kao, W.H, Chonchol, Michel, Haritunians, Talin, Li, Guo, Lumley, Thomas, Psaty, Bruce M, Shlipak, Michael, Hwang, Shih-Jen, Larson, Martin G, OʼDonnell, Christopher J, Upadhyay, Ashish, van Duijn, Cornelia M, Hofman, Albert, Rivadeneira, Fernando, Stricker, Bruno, Uitterlinden, Andre G, Paré, Guillaume, Parker, Alex N, Ridker, Paul M, Siscovick, David S, Gudnason, Vilmundur, Witteman, Jacqueline C, Fox, Caroline S, Coresh, Josef

“…BACKGROUND—Elevated serum urate levels can lead to gout and are associated with cardiovascular risk factors. We performed a genome-wide association study to…”
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Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans by Lipkowitz, Michael S, Freedman, Barry I, Langefeld, Carl D, Comeau, Mary E, Bowden, Donald W, Kao, W H Linda, Astor, Brad C, Bottinger, Erwin P, Iyengar, Sudha K, Klotman, Paul E, Freedman, Richard G, Zhang, Weijia, Parekh, Rulan S, Choi, Michael J, Nelson, George W, Winkler, Cheryl A, Kopp, Jeffrey B

“…Despite intensive antihypertensive therapy there was a high incidence of renal end points in participants of the African American Study of Kidney Disease and…”
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A pseudolikelihood approach for assessing genetic association in case–control studies with unmeasured population structure by Chen, Yong, Liang, Kung-Yee, Tong, Pan, Beaty, Terri H, Barnes, Kathleen C, Linda Kao, WH

“…The case–control study design is one of the main tools for detecting associations between genetic markers and diseases. It is well known that population…”
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Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity by Erlich, Porat M, Hoffman, Stuart N, Rukstalis, Margaret, Han, John J, Chu, Xin, Linda Kao, W. H, Gerhard, Glenn S, Stewart, Walter F, Boscarino, Joseph A

“…A locus on chromosome 15q25.1 previously implicated in nicotine, alcohol, and cocaine dependence, smoking, and lung cancer encodes subunits of the nicotinic…”
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Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes by Qi, Lu, Cornelis, Marilyn C., Kraft, Peter, Stanya, Kristopher J., Linda Kao, W.H., Pankow, James S., Dupuis, Josée, Florez, Jose C., Fox, Caroline S., Paré, Guillaume, Sun, Qi, Girman, Cynthia J., Laurie, Cathy C., Mirel, Daniel B., Manolio, Teri A., Chasman, Daniel I., Boerwinkle, Eric, Ridker, Paul M., Hunter, David J., Meigs, James B., Lee, Chih-Hao, van Dam, Rob M., Hu, Frank B.

“…To identify type 2 diabetes (T2D) susceptibility loci, we conducted genome-wide association (GWA) scans in nested case–control samples from two prospective…”
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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study by Dehghan, Abbas, MD, Köttgen, Anna, MD, Yang, Qiong, PhD, Hwang, Shih-Jen, PhD, Kao, WH Linda, PhD, Rivadeneira, Fernando, MD, Boerwinkle, Eric, PhD, Levy, Daniel, MD, Hofman, Albert, MD, Astor, Brad C, PhD, Benjamin, Emelia J, MD, van Duijn, Cornelia M, PhD, Witteman, Jacqueline C, PhD, Coresh, Josef, MD, Fox, Caroline S, Dr

“…Summary Background Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes associated with serum uric acid…”
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The MYH9/APOL1 region and chronic kidney disease in European-Americans by O'Seaghdha, Conall M, Parekh, Rulan S, Hwang, Shih-Jen, Li, Man, Köttgen, Anna, Coresh, Josef, Yang, Qiong, Fox, Caroline S, Kao, W H Linda

“…Polymorphisms in the MYH9 and adjacent APOL1 gene region demonstrate a strong association with non-diabetic kidney disease in African-Americans. However, it is…”
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Common variants in KCNN3 are associated with lone atrial fibrillation by Topol, Eric J, Moebus, Susanne, Rice, Kenneth M, Smith, Jonathan D, Lunetta, Kathryn L, Uitterlinden, André G, Milan, David J, Schnabel, Renate B, Launer, Lenore J, Köttgen, Anna, Esko, Tõnu, Wang, Thomas J, Soliman, Elsayed Z, Gudnason, Vilmundur, Boerwinkle, Eric, Pfeufer, Arne, Barnard, John, Harris, Tamara B, Levy, Daniel, Ch Stricker, Bruno H, van Noord, Charlotte, Alonso, Alvaro, Linda Kao, W H, Van Wagoner, David R, Meitinger, Thomas, Chung, Mina K, Wichmann, H-Erich, Fox, Ervin, Steinbeck, Gerhard, Newton-Cheh, Christopher, de Bakker, Paul I W, Nelis, Mari, Beckmann, Britt-M, Mueller, Martina, MacRae, Calum A, Heckbert, Susan R, Möhlenkamp, Stefan, Kääb, Stefan, Smith, Albert V, Smith, Nicholas L, Glazer, Nicole L, Metspalu, Andres, Vasan, Ramachandran S, Li, Man, Lubitz, Steven A, Hazen, Stanley L, Psaty, Bruce M, Wang, Ke, Chakravarti, Aravinda, Ellinor, Patrick T, Sinner, Moritz F, Perz, Siegfried, Makino, Seiko, Benjamin, Emelia J, Ehret, Georg B, Hofman, Albert, Nöthen, Markus M, Roden, Dan M, Witteman, Jacqueline C M, Darbar, Dawood, Arking, Dan E, Rotter, Jerome I

“…Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous studies have identified several genetic loci associated with typical AF. We sought…”
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Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish by Maruthur, Nisa M., Clark, Jeanne M., Fu, Mao, Linda Kao, W. H., Shuldiner, Alan R.

“…Aims/hypothesis SLC30A8 encodes a zinc transporter in the beta cell; individuals with a common missense variant (rs13266634; R325W) in SLC30A8 demonstrate a…”
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Frailty and Cognitive Function in Incident Hemodialysis Patients by McAdams-DeMarco, Mara A, Tan, Jingwen, Salter, Megan L, Gross, Alden, Meoni, Lucy A, Jaar, Bernard G, Kao, Wen-Hong Linda, Parekh, Rulan S, Segev, Dorry L, Sozio, Stephen M

“…Patients of all ages undergoing hemodialysis (HD) have a high prevalence of cognitive impairment and worse cognitive function than healthy controls, and those…”
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Beyond ultrasound: CT and MRI of ectopic pregnancy by Kao, Linda Y, Scheinfeld, Meir H, Chernyak, Victoria, Rozenblit, Alla M, Oh, Sarah, Dym, R Joshua

“…Although ultrasound is the primary modality used in the diagnosis of ectopic pregnancy, various forms of this condition and their complications may…”
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The Pharmacogenetics of Type 2 Diabetes: A Systematic Review by MARUTHUR, Nisa M, GRIBBLE, Matthew O, BENNETT, Wendy L, BOLEN, Shari, WILSON, Lisa M, BALAKRISHNAN, Poojitha, SAHU, Anita, BASS, Eric, KAO, W. H. LINDA, CLARK, Jeanne M

“…We performed a systematic review to identify which genetic variants predict response to diabetes medications. We performed a search of electronic databases…”
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Age and Sex Disparities in Discussions About Kidney Transplantation in Adults Undergoing Dialysis by Salter, Megan L., McAdams-Demarco, Mara A., Law, Andrew, Kamil, Rebecca J., Meoni, Lucy A., Jaar, Bernard G., Sozio, Stephen M., Linda Kao, Wen Hong, Parekh, Rulan S., Segev, Dorry L.

“…Objectives To explore whether disparities in age and sex in access to kidney transplantation (KT) originate at the time of prereferral discussions about KT…”
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Biomarkers of vascular calcification and mortality in patients with ESRD by Scialla, Julia J, Kao, W H Linda, Crainiceanu, Ciprian, Sozio, Stephen M, Oberai, Pooja C, Shafi, Tariq, Coresh, Josef, Powe, Neil R, Plantinga, Laura C, Jaar, Bernard G, Parekh, Rulan S

“…Vascular calcification is common among patients undergoing dialysis and is associated with mortality. Factors such as osteoprotegerin (OPG), osteopontin (OPN),…”
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Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study by Bressler, Jan, Kao, W H Linda, Pankow, James S, Boerwinkle, Eric

“…Single nucleotide polymorphisms (SNPs) in the fat mass and obesity associated (FTO) gene are associated with body mass index (BMI) in populations of European…”
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Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility by Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Dauriz, Marco, Raghavan, Sridharan, Hidalgo, Bertha, An, Ping, Lu, Yingchang, Ehm, Margaret G, Baldridge, Abigail S, Freitag, Daniel F, Garcia, Melissa E, Hara, Kazuo, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Morrison, Alanna C, Peters, Marjolein J, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Varga, Tibor V, Barbieri, Caterina, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Frånberg, Mattias, Gambaro, Giovanni, Goel, Anuj, Grove, Megan L, Karaleftheri, Maria, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, I T, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Lindgren, Cecilia M, Malerba, Giovanni, Mamakou, Vasiliki, Maruthur, Nisa M, McLeod, Olga, Mohlke, Karen L, Muzny, Donna M, Renström, Frida, Rice, Ken, Sala, Cinzia F, Soranzo, Nicole, Speliotes, Elizabeth K, Stirrups, Kathleen, Thanopoulou, Anastasia, Traglia, Michela, Tsafantakis, Emmanouil, Javad, Sundas, Yanek, Lisa R, Becker, Diane M, Bis, Joshua C, Brown, James B, Ingelsson, Erik, Karter, Andrew J, Lorenzo, Carlos, Peloso, Gina M, Vaidya, Dhananjay, Varma, Rohit, Wagenknecht, Lynne E, Dedoussis, George, Deloukas, Panos, Franco, Oscar H, Gibbs, Richard A, Gudnason, Vilmundur, Hofman, Albert, Jansson, Jan-Håkan, Langenberg, Claudia, Launer, Lenore J, Levy, Daniel, Oostra, Ben A, Padmanabhan, Sandosh, Pankow, James S, Rudan, Igor, Schulze, Matthias B, Smith, Blair H, Walker, Mark, Wong, Tien Y, Laakso, Markku, Borecki, Ingrid B, van Duijn, Cornelia M, Waterworth, Dawn M, Loos, Ruth J.F., Meigs, James B, Scott, Robert A, Goodarzi, Mark O

“…Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants…”
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Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene by Reich, David, Nalls, Michael A, Kao, W H Linda, Akylbekova, Ermeg L, Tandon, Arti, Patterson, Nick, Mullikin, James, Hsueh, Wen-Chi, Cheng, Ching-Yu, Coresh, Josef, Boerwinkle, Eric, Li, Man, Waliszewska, Alicja, Neubauer, Julie, Li, Rongling, Leak, Tennille S, Ekunwe, Lynette, Files, Joe C, Hardy, Cheryl L, Zmuda, Joseph M, Taylor, Herman A, Ziv, Elad, Harris, Tamara B, Wilson, James G

“…Persistently low white blood cell count (WBC) and neutrophil count is a well-described phenomenon in persons of African ancestry, whose etiology remains…”
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Pleiotropic genes for metabolic syndrome and inflammation by Kraja, Aldi T., Chasman, Daniel I., North, Kari E., Reiner, Alexander P., Yanek, Lisa R., Kilpeläinen, Tuomas O., Smith, Jennifer A., Dehghan, Abbas, Dupuis, Josée, Johnson, Andrew D., Feitosa, Mary F., Tekola-Ayele, Fasil, Chu, Audrey Y., Nolte, Ilja M., Dastani, Zari, Morris, Andrew, Pendergrass, Sarah A., Sun, Yan V., Ritchie, Marylyn D., Vaez, Ahmad, Lin, Honghuang, Ligthart, Symen, Marullo, Letizia, Rohde, Rebecca, Shao, Yaming, Ziegler, Mark A., Im, Hae Kyung, Schnabel, Renate B., Jørgensen, Torben, Jørgensen, Marit E., Hansen, Torben, Pedersen, Oluf, Stolk, Ronald P., Snieder, Harold, Hofman, Albert, Uitterlinden, Andre G., Franco, Oscar H., Ikram, M. Arfan, Richards, J. Brent, Rotimi, Charles, Wilson, James G., Lange, Leslie, Ganesh, Santhi K., Nalls, Mike, Rasmussen-Torvik, Laura J., Pankow, James S., Coresh, Josef, Tang, Weihong, Linda Kao, W.H., Boerwinkle, Eric, Morrison, Alanna C., Ridker, Paul M., Becker, Diane M., Rotter, Jerome I., Kardia, Sharon L.R., Loos, Ruth J.F., Larson, Martin G., Hsu, Yi-Hsiang, Province, Michael A., Tracy, Russell, Voight, Benjamin F., Vaidya, Dhananjay, O'Donnell, Christopher J., Benjamin, Emelia J., Alizadeh, Behrooz Z., Prokopenko, Inga, Meigs, James B., Borecki, Ingrid B.

“…Metabolic syndrome (MetS) has become a health and financial burden worldwide. The MetS definition captures clustering of risk factors that predict higher risk…”
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Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD by KÖTTGEN, Anna, HWANG, Shih-Jen, GUDNASON, Vilmundur, SHLIPAK, Michael G, QIONG YANG, CORESH, Josef, LEVY, Daniel, FOX, Caroline S, LARSON, Martin G, VAN EYK, Jennifer E, QIN FU, BENJAMIN, Emelia J, DEHGHAN, Abbas, GLAZER, Nicole L, LINDA KAO, W. H, HARRIS, Tamara B

“…Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR…”
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