Search Results - "Kao, Katy C."

Molecular characterization of clonal interference during adaptive evolution in asexual populations of Saccharomyces cerevisiae by Sherlock, Gavin, Kao, Katy C

“…The classical model of adaptive evolution in an asexual population postulates that each adaptive clone is derived from the one preceding it. However,…”
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Adaptive laboratory evolution of β-caryophyllene producing Saccharomyces cerevisiae by Godara, Avinash, Kao, Katy C.

“…Abstract Background β-Caryophyllene is a plant terpenoid with therapeutic and biofuel properties. Production of terpenoids through microbial cells is a…”
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Recent advances in the evolutionary engineering of industrial biocatalysts by Winkler, James D., Kao, Katy C.

“…Evolutionary engineering has been used to improve key industrial strain traits, such as carbon source utilization, tolerance to adverse environmental…”
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Adaptive laboratory evolution for growth coupled microbial production by Godara, Avinash, Kao, Katy C.

“…Adaptive laboratory evolution (ALE) is a powerful tool to select for strains with growth-coupled phenotypes. When coupled with next-generation sequencing and…”
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Genomic library screens for genes involved in n-butanol tolerance in Escherichia coli by Reyes, Luis H, Almario, Maria P, Kao, Katy C

“…n-Butanol is a promising emerging biofuel, and recent metabolic engineering efforts have demonstrated the use of several microbial hosts for its production…”
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Transcriptional analysis of Lactobacillus brevis to N-butanol and ferulic acid stress responses by Winkler, James, Kao, Katy C

“…The presence of anti-microbial phenolic compounds, such as the model compound ferulic acid, in biomass hydrolysates pose significant challenges to the…”
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Genetic Determinants for n-Butanol Tolerance in Evolved Escherichia coli Mutants: Cross Adaptation and Antagonistic Pleiotropy between n-Butanol and Other Stressors by REYES, Luis H, ABDELAAL, Ali S, KAO, Katy C

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Sexual recombination and increased mutation rate expedite evolution of Escherichia coli in varied fitness landscapes by Peabody V, George L., Li, Hao, Kao, Katy C.

“…Sexual recombination and mutation rate are theorized to play different roles in adaptive evolution depending on the fitness landscape; however, direct…”
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A genome-wide analysis reveals no nuclear dobzhansky-muller pairs of determinants of speciation between S. cerevisiae and S. paradoxus, but suggests more complex incompatibilities by Kao, Katy C, Schwartz, Katja, Sherlock, Gavin

“…The Dobzhansky-Muller (D-M) model of speciation by genic incompatibility is widely accepted as the primary cause of interspecific postzygotic isolation. Since…”
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Visualizing evolution in real time to determine the molecular mechanisms of n-butanol tolerance in Escherichia coli by Reyes, Luis H., Almario, Maria P., Winkler, James, Orozco, Margarita M., Kao, Katy C.

“…Toxicity of products or feedstock components poses a challenge in the biocatalyst-based production of fuels and chemicals. The genetic determinants that are…”
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Antibiofilm Activity of PDMS/TiO2 against Candida glabrata through Inhibited Hydrophobic Recovery by Nguyen, Khoi-Nguyen, Sao, Leena, Kyllo, Kevin, Hernandez, Danitza, Salomon, Samantha, Shah, Kalp, Oh, Dahyun, Kao, Katy C.

“…Coatings with antibiofilm properties are desirable for biomedical applications. Titanium dioxide (TiO2) has been explored as an antimicrobial agent in…”
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Characterization of an evolved carotenoids hyper-producer of Saccharomyces cerevisiae through bioreactor parameter optimization and Raman spectroscopy by Olson, Michelle L., Johnson, James, Carswell, William F., Reyes, Luis H., Senger, Ryan S., Kao, Katy C.

“…An evolutionary engineering approach for enhancing heterologous carotenoids production in an engineered Saccharomyces cerevisiae strain was used previously to…”
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Evolutionary Dynamics of Candida albicans during In Vitro Evolution by Huang, Mian, McClellan, Mark, Berman, Judith, Kao, Katy C

“…While mechanisms of resistance to major antifungal agents have been characterized in Candida albicans, little is known about the evolutionary trajectories…”
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Global Expression Profiling of Acetate-grown Escherichia coli by Oh, Min-Kyu, Rohlin, Lars, Kao, Katy C., Liao, James C.

“…This study characterized the transcript profile of Escherichia coli in acetate cultures using DNA microarray on glass slides. Glucose-grown cultures were used…”
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Insights on Osmotic Tolerance Mechanisms in Escherichia coli Gained from an rpoC Mutation by Guo, Yuqi, Winkler, James, Kao, Katy C

“…An 84 bp in-frame duplication (K370_A396dup) within the rpoC subunit of RNA polymerase was found in two independent mutants selected during an adaptive…”
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Effects of Seawater on Carotenoid Production and Lipid Content of Engineered Saccharomyces cerevisiae by Guo, Yuqi, Xie, Shangxian, Yuan, Joshua S., Kao, Katy C.

“…The use of seawater in fermentation can potentially reduce the freshwater burden in the bio-based production of chemicals and fuels. We previously developed a…”
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A Global Regulatory Role of Gluconeogenic Genes in Escherichia coli Revealed by Transcriptome Network Analysis by Kao, Katy C., Tran, Linh M., Liao, James C.

“…In bacterial adaptation to the dynamic environment, metabolic genes are typically thought to be the executors, whereas global transcription regulators are…”
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Transcriptome-Based Determination of Multiple Transcription Regulator Activities in Escherichia coli by Using Network Component Analysis by Kao, Katy C., Yang, Young-Lyeol, Boscolo, Riccardo, Sabatti, Chiara, Roychowdhury, Vwani, Liao, James C.

“…Cells adjust gene expression profiles in response to environmental and physiological changes through a series of signal transduction pathways. Upon activation…”
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Visualizing evolution in real-time method for strain engineering by Reyes, Luis H, Winkler, James, Kao, Katy C

“…The adaptive landscape for an industrially relevant phenotype is determined by the effects of the genetic determinants on the fitness of the microbial system…”
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Relative Abundances of Candida albicans and Candida glabrata in In Vitro Coculture Biofilms Impact Biofilm Structure and Formation by Olson, Michelle L, Jayaraman, Arul, Kao, Katy C

“…is a member of the normal human microbiota and often resides on mucosal surfaces such as the oral cavity or the gastrointestinal tract. In addition to their…”
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