Search Results - "Kao, Iris"

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding by Bhang, Hyo-eun C, Ruddy, David A, Krishnamurthy Radhakrishna, Viveksagar, Caushi, Justina X, Zhao, Rui, Hims, Matthew M, Singh, Angad P, Kao, Iris, Rakiec, Daniel, Shaw, Pamela, Balak, Marissa, Raza, Alina, Ackley, Elizabeth, Keen, Nicholas, Schlabach, Michael R, Palmer, Michael, Leary, Rebecca J, Chiang, Derek Y, Sellers, William R, Michor, Franziska, Cooke, Vesselina G, Korn, Joshua M, Stegmeier, Frank

“…The authors have developed a barcoded library that enables the high-throughput tracking of tumor cell dynamics and clonal evolution in response to therapy…”
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A chemical genetics approach for the functional assessment of novel cancer genes by Zhou, Qianhe, Derti, Adnan, Ruddy, David, Rakiec, Daniel, Kao, Iris, Lira, Michelle, Gibaja, Veronica, Chan, HoMan, Yang, Yi, Min, Junxia, Schlabach, Michael R, Stegmeier, Frank

“…Assessing the functional significance of novel putative oncogenes remains a significant challenge given the limitations of current loss-of-function tools…”
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Abstract 3240: Understanding clonal complexity of a tumor xenograft model via cellular barcoding technology by Caushi, Justina X., Bhang, Hyo-eun C., Li, Jie, Kao, Iris, Krishnamurthy Radhakrishna, Viveksagar, Cooke, Vesselina G., Korn, Joshua M., Ruddy, David A., Kasibhatla, Shailaja, Stegmeier, Frank

“…Abstract Recent advances in next-generation sequencing have revealed the presence of genetic heterogeneity and clonal evolution within tumors. Intratumoral…”
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Abstract 2847: High complexity barcoding to study clonal dynamics in response to cancer therapy by Bhang, Hyo-eun C., Ruddy, David A., Krishnamurthy Radhakrishna, Viveksagar, Zhao, Rui, Kao, Iris, Rakiec, Daniel, Shaw, Pamela, Balak, Marissa, Caushi, Justina X., Ackley, Elizabeth, Keen, Nicholas, Schlabach, Michael R., Palmer, Michael, Sellers, William R., Michor, Franziska, Cooke, Vesselina G., Korn, Joshua M., Stegmeier, Frank

“…Abstract Targeted therapies, such as erlotinib and imatinib, lead to dramatic clinical responses, but the emergence of resistance presents a significant…”
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A Question-Answer Driven Approach to Reveal Affirmative Interpretations from Verbal Negations by Hossain, Md Mosharaf, Holman, Luke, Kakileti, Anusha, Kao, Tiffany Iris, Brito, Nathan Raul, Mathews, Aaron Abraham, Blanco, Eduardo

“…This paper explores a question-answer driven approach to reveal affirmative interpretations from verbal negations (i.e., when a negation cue grammatically…”
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