Search Results - "Kanthlal, S. K."
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Exploring the effects of vasoactive constituents in large cardamom: implications for the anti-hypertensive effect via eNOS coupling pathway - an in-vitro study in rat endothelial cells
Published in Natural product research (14-05-2024)“…Endothelial dysfunction, linked to reduced eNOS expression and nitric oxide (NO) availability, contributes to cardiovascular diseases (CVDs). Large cardamom…”
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Renin-angiotensin system modulators in COVID-19 patients with hypertension: friend or foe?
Published in Clinical and experimental hypertension (1993) (02-01-2022)“…Background: ACE2, a component of the non-classic renin-angiotensin system (RAS), acts as a functional receptor for severe acute respiratory syndrome…”
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Antioxidant and vasorelaxant effects of aqueous extract of large cardamom in L-NAME induced hypertensive rats
Published in Clinical and experimental hypertension (1993) (02-10-2020)“…The present work aimed to study the effect of aqueous extract of large cardamom (AELC) to prevent vascular remodeling and oxidative stress in N ω…”
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Clozapine Disrupts Endothelial Nitric Oxide Signaling and Antioxidant System for its Cardiovascular Complications
Published in Drug research (01-12-2019)“…Many drugs in current practice require additional safety labels in order to prevent potential risks to the major organ system. Psychotropic agent clozapine has…”
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Unveiling the therapeutic potential of plant steroid peimine: A study on apoptotic induction in MRMT-1 cell line-induced breast cancer in rats
Published in Steroids (01-09-2024)“…[Display omitted] Breast cancer stands as a leading contributor to global cancer-related mortality. Progressing Research and Medical Innovations Elevate…”
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Leptin Receptors can be an Alternative Target for New Anti-hypertensive Drug Development
Published in Indian journal of endocrinology and metabolism (01-11-2017)“…[4] Hence in normotensive men AGT levels are related to both fat mass and plasma leptin levels, and there is a significant positive relationship between plasma…”
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Aqueous extract of large cardamom inhibits vascular damage, oxidative stress, and metabolic changes in fructose-fed hypertensive rats
Published in Clinical and experimental hypertension (1993) (03-10-2021)“…Since metabolic abnormalities such as elevated glucose level and imbalanced lipid profiles increase the risk for hypertension and cause endothelial…”
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The role of dietary polyphenols in inflammatory bowel disease: A possible clue on the molecular mechanisms involved in the prevention of immune and inflammatory reactions
Published in Journal of food biochemistry (01-11-2020)“…Inflammatory bowel disease (IBD) is one of the major complications of the gastrointestinal tract, characterized by chronic inflammation, which disturbs the…”
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Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders
Published in CNS & neurological disorders drug targets (01-01-2024)“…The flavoenzyme monoamine oxidases (MAOs) are present in the mitochondrial outer membrane and are responsible for the metabolism of biogenic amines. MAO…”
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Apoptosis promoting activity of selected plant steroid in MRMT-1 breast cancer cell line by modulating mitochondrial permeation pathway
Published in Steroids (01-02-2023)“…•Phytosterols are Plant-derived compounds that can combat cancer via multiple pathways.•Docking, ADMET, and drug-likeness study reveals peimine a potent…”
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Peptides: A Supercilious Candidate for Activating Intrinsic Apoptosis by Targeting Mitochondrial Membrane Permeability for Cancer Therapy
Published in International journal of peptide research and therapeutics (01-12-2021)“…Escape from apoptosis is one of the main demeanor characters of cancer cells. Mitochondria is a key player in the initiation and regulation intrinsic…”
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Dietary foods containing nitric oxide donors can be early curators of SARS‐CoV‐2 infection: A possible role in the immune system
Published in Journal of food biochemistry (01-03-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2) is a lethal virus that causes COVID‐19 (Coronavirus disease 2019), the respiratory illness that…”
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Targeting Viral ORF3a Protein: A New Approach to Mitigate COVID-19 Induced Immune Cell Apoptosis and Associated Respiratory Complications
Published in Advanced pharmaceutical bulletin (01-11-2023)“…Infection with SARS-CoV-2 is a growing concern to the global well-being of the public at present. Different amino acid mutations alter the biological and…”
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The Role of Mitochondrial Genes in Neurodegenerative Disorders
Published in Current neuropharmacology (01-01-2022)“…Mitochondrial disorders are clinically heterogeneous, resulting from nuclear gene and mitochondrialmutations that disturb the mitochondrial functions and…”
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Clozapine Disrupts Endothelial Nitric Oxide Signaling and Antioxidant System for its Cardiovascular Complications
Published in Journal of young pharmacists (01-01-2019)Get full text
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Vascular targeting of constituents of commonly used spices and its molecular interactions in endothelial dysfunction: A review
Published in Phytochemistry reviews (28-03-2024)Get full text
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Amelioration of oxidative stress by Tabernamontana divaricata on alloxan-induced diabetic rats
Published in Ancient science of life (01-04-2014)“…The purpose of this study was to evaluate the anti-diabetic activity of ethanol extract of Tabernamontana divaricata (L.) and its ameliorative effect on…”
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Amelioration of oxidative stress by Tabernamontana divaricataon alloxan-induced diabetic rats
Published in Ancient science of life (01-10-2014)“…Objective: The purpose of this study was to evaluate the anti-diabetic activity of ethanol extract of Tabernamontana divaricata (L.) and its ameliorative…”
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