Search Results - "Kanta De, Chandra"
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Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
Published in Angewandte Chemie International Edition (09-11-2020)“…We disclose a new Brønsted acid promoted quinoline synthesis, proceeding via homo‐diaza‐Cope rearrangement of N‐aryl‐N′‐cyclopropyl hydrazines. Our strategy…”
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Strong and Confined Acids Control Five Stereogenic Centers in Catalytic Asymmetric Diels–Alder Reactions of Cyclohexadienones with Cyclopentadiene
Published in Angewandte Chemie International Edition (20-07-2020)“…We describe a highly enantioselective Diels–Alder reaction of cross‐conjugated cyclohexadienones with cyclopentadiene, in which five stereocenters are…”
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Strong and Confined Acids Enable a Catalytic Asymmetric Nazarov Cyclization of Simple Divinyl Ketones
Published in Journal of the American Chemical Society (27-02-2019)“…We report a catalytic asymmetric Nazarov cyclization of simple, acylic, alkyl-substituted divinyl ketones using our recently disclosed strong and confined…”
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4
Approaching sub-ppm-level asymmetric organocatalysis of a highly challenging and scalable carbon–carbon bond forming reaction
Published in Nature chemistry (01-08-2018)“…The chemical synthesis of organic molecules involves, at its very essence, the creation of carbon–carbon bonds. In this context, the aldol reaction is among…”
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Catalytic enantiocontrol over a non-classical carbocation
Published in Nature chemistry (01-12-2020)“…Carbocations can be categorized into classical carbenium ions and non-classical carbonium ions. These intermediates are ubiquitous in reactions of both…”
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6
The Smelling Principle of Vetiver Oil, Unveiled by Chemical Synthesis
Published in Angewandte Chemie International Edition (08-03-2021)“…Vetiver oil, produced on a multiton‐scale from the roots of vetiver grass, is one of the finest and most popular perfumery materials, appearing in over a third…”
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A dual-catalysis approach to the kinetic resolution of 1,2-diaryl-1,2-diaminoethanes
Published in Chemical communications (Cambridge, England) (01-01-2012)“…The kinetic resolution of racemic C(2)-symmetric 1,2-diaryl-1,2-diaminoethanes was accomplished for the first time through application of a dual-catalysis…”
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8
Asymmetric counteranion-directed photoredox catalysis
Published in Science (American Association for the Advancement of Science) (03-02-2023)“…Photoredox catalysis enables distinctive and broadly applicable chemical reactions, but controlling their selectivity has proven to be difficult. The pursuit…”
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Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
Published in Journal of the American Chemical Society (18-03-2015)“…An asymmetric Brønsted acid catalyzed dearomatizing redox cross coupling reaction has been realized, in which aryl hydrazines react with ketones to deliver…”
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10
Catalytic Enantioselective Desymmetrization of meso-Diamines: A Dual Small-Molecule Catalysis Approach
Published in Journal of the American Chemical Society (21-09-2011)“…The desymmetrization of meso-diamines was accomplished via enantioselective monobenzoylation facilitated by the cooperative action of two small-molecule…”
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Organocatalytic stereoselective cyanosilylation of small ketones
Published in Nature (London) (05-05-2022)“…Enzymatic stereoselectivity has typically been unrivalled by most chemical catalysts, especially in the conversion of small substrates. According to the…”
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12
A Dual-Catalysis Approach to the Asymmetric Steglich Rearrangement and Catalytic Enantioselective Addition of O-Acylated Azlactones to Isoquinolines
Published in Journal of the American Chemical Society (26-10-2011)“…A dual-catalysis approach, namely the combination of an achiral nucleophilic catalyst and a chiral anion-binding catalyst, was applied to the Steglich…”
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13
Taming secondary benzylic cations in catalytic asymmetric SN1 reactions
Published in Science (American Association for the Advancement of Science) (20-10-2023)“…Editor’s summaryNucleophilic substitution reactions are widely used to form bonds to carbon. In many cases, the reactions occur with precisely predictable…”
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Merging Nucleophilic and Hydrogen Bonding Catalysis: An Anion Binding Approach to the Kinetic Resolution of Amines
Published in Journal of the American Chemical Society (02-12-2009)“…A new concept for asymmetric nucleophilic catalysis is presented. Acyl pyridinium salts derived from 4-(dimethylamino)pyridine (DMAP) and benzoic anhydride are…”
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Nitrated Confined Imidodiphosphates Enable a Catalytic Asymmetric Oxa-Pictet–Spengler Reaction
Published in Journal of the American Chemical Society (03-08-2016)“…The development of a highly enantioselective catalytic oxa-Pictet–Spengler reaction has proven a great challenge for chemical synthesis. We now report the…”
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Merging Nucleophilic and Hydrogen Bonding Catalysis: An Anion Binding Approach to the Kinetic Resolution of Propargylic Amines
Published in Journal of the American Chemical Society (06-10-2010)“…An efficient kinetic resolution of primary propargylic amines with s-factors of up to 56 is reported. The strategy is based on a dual catalytic approach,…”
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17
Asymmetric Catalysis of the Carbonyl-Amine Condensation: Kinetic Resolution of Primary Amines
Published in Journal of the American Chemical Society (01-02-2017)“…A Brønsted acid catalyzed kinetic resolution of primary amines is described that is based on the condensation between an amine and a carbonyl compound…”
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18
Frontispiece: The Smelling Principle of Vetiver Oil, Unveiled by Chemical Synthesis
Published in Angewandte Chemie International Edition (08-03-2021)“…Fragrance Chemistry In their Communication on page 5666, Philip Kraft, Benjamin List et al. describe a concise stereoselective total synthesis of…”
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Harnessing the ambiphilicity of silyl nitronates in a catalytic asymmetric approach to aliphatic β3-amino acids
Published in Nature catalysis (02-12-2021)“…Nitronate anions, formally generated by α-deprotonating the corresponding nitroalkanes, are highly nucleophilic and versatile intermediates in many…”
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Starke und sterisch begrenzte Säuren kontrollieren fünf stereogene Zentren in der katalytischen asymmetrischen Diels‐Alder‐Reaktion von Cyclohexadienonen mit Cyclopentadien
Published in Angewandte Chemie (20-07-2020)“…Wir stellen eine hochenantioselektiven Diels‐Alder‐Reaktion zwischen kreuzkonjugierten Cyclohexadienonen und Cyclopentadien vor, in der fünf Stereozentren…”
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