Search Results - "Kant, Rajeev"
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Paramagnetic Properties of Metal‐Free Boron‐Doped Graphene Quantum Dots and Their Application for Safe Magnetic Resonance Imaging
Published in Advanced materials (Weinheim) (01-03-2017)“…A boron‐doped graphene quantum dot (B‐GQD) as a metal‐free multimodal contrast agent (CA) for safe magnetic resonance imaging and fluorescence imaging is…”
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Metformin Preconditioning Augments Cardiac Perfusion and Performance in a Large Animal Model of Chronic Coronary Artery Disease
Published in Annals of surgery (01-10-2024)“…To test the efficacy of metformin during the induction of coronary ischemia on myocardial performance in a large animal model of coronary artery disease (CAD)…”
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Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts
Published in Biomaterials (01-08-2020)“…Heart regeneration after myocardial infarction requires new cardiomyocytes and a supportive vascular network. Here, we evaluate the efficacy of localized…”
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Integrated approaches to spatiotemporally directing angiogenesis in host and engineered tissues
Published in Acta biomaterialia (15-03-2018)“…[Display omitted] The field of tissue engineering has turned towards biomimicry to solve the problem of tissue oxygenation and nutrient/waste exchange through…”
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Anti-HER2/neu peptide-conjugated iron oxide nanoparticles for targeted delivery of paclitaxel to breast cancer cells
Published in Nanoscale (21-11-2015)“…Nanoparticles (NPs) for targeted therapy are required to have appropriate size, stability, drug loading and release profiles, and efficient targeting ligands…”
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A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues
Published in Scientific reports (13-05-2021)“…Cardiotoxicity of pharmaceutical drugs, industrial chemicals, and environmental toxicants can be severe, even life threatening, which necessitates a thorough…”
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Optimizing Blended Collagen-Fibrin Hydrogels for Cardiac Tissue Engineering with Human iPSC-derived Cardiomyocytes
Published in ACS biomaterials science & engineering (11-02-2019)“…Natural polymer hydrogels are used ubiquitously as scaffold materials for cardiac tissue engineering as well as for soft tissue engineering more broadly…”
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Tissues with Patterned Vessels or Protein Release Induce Vascular Chemotaxis in an In Vitro Platform
Published in Tissue engineering. Part A (01-10-2021)“…Engineered tissues designed for translational applications in regenerative medicine require vascular networks to deliver oxygen and nutrients rapidly to the…”
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Digital Design and Automated Fabrication of Bespoke Collagen Microfiber Scaffolds
Published in Tissue engineering. Part C, Methods (01-11-2019)“…A great variety of natural and synthetic polymer materials have been utilized in soft tissue engineering as extracellular matrix (ECM) materials. Natural…”
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Patterned Arteriole-Scale Vessels Enhance Engraftment, Perfusion, and Vessel Branching Hierarchy of Engineered Human Myocardium for Heart Regeneration
Published in Cells (Basel, Switzerland) (23-06-2023)“…Heart regeneration after myocardial infarction (MI) using human stem cell-derived cardiomyocytes (CMs) is rapidly accelerating with large animal and human…”
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One Billion hiPSC-Cardiomyocytes: Upscaling Engineered Cardiac Tissues to Create High Cell Density Therapies for Clinical Translation in Heart Regeneration
Published in Bioengineering (Basel) (13-05-2023)“…Despite the overwhelming use of cellularized therapeutics in cardiac regenerative engineering, approaches to biomanufacture engineered cardiac tissues (ECTs)…”
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12
Retrieval of a broken guide wire transfixing the hip through the proximal femoral nail hole
Published in Chinese journal of traumatology (01-02-2014)“…Retrieval of a broken guide wire transfix- ing the acetabulum or with intrapelvic migration is challeng- ing and frustrating for surgeons. We here present a…”
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Abstract P1140: Scaling Up Engineered Cardiac Tissue For Clinical Translation As A Regenerative Therapy
Published in Circulation research (05-08-2022)“…Advances in cardiovascular interventions have significantly decreased mortality due to acute myocardial infarction (MI). However, heart failure (HF) as a main…”
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Abstract P1032: Patterned Vessels In HIPSC-derived Engineered Myocardium Enhance Perfusion And Heart Regeneration In A Rat Myocardial Infarction Model
Published in Circulation research (05-08-2022)“…Globally, >6 million patients with heart failure (HF) have reduced ejection fraction due to prior myocardial infarction (MI). In the U.S., 50,000 become…”
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Abstract P1129: Directing Revascularization In Vivo With Local Controlled Release Of An Optimized Angiogenic Growth Factor Cocktail
Published in Circulation research (04-08-2023)“…Abstract only Reduced vascular perfusion due to aging, ischemia, or injury impedes healing and tissue function in conditions like skin ulcers and myocardial…”
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Sequential optimisation of reconfigurable machine cell feeders and production sequence during lean assembly
Published in International journal of computer integrated manufacturing (02-01-2020)“…This paper presents a manufacturing model for integrating reconfigurable machine cells as feeders of components to a multi-product assembly line exhibiting a…”
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Abstract 716: 2D and 3D Assessment of Angiogenesis in Cardiac Engineered Tissues Implanted on Infarcted Rat Hearts
Published in Circulation research (02-08-2019)“…Abstract only A lack of efficient vessel perfusion in cardiac engineered tissues affects cell viability and limits the success of implanted cardiac tissues. To…”
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