Search Results - "Kannan, Sadhana"

Prostate-Only Versus Whole-Pelvic Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer (POP-RT): Outcomes From Phase III Randomized Controlled Trial by Murthy, Vedang, Maitre, Priyamvada, Kannan, Sadhana, Panigrahi, Gitanjali, Krishnatry, Rahul, Bakshi, Ganesh, Prakash, Gagan, Pal, Mahendra, Menon, Santosh, Phurailatpam, Reena, Mokal, Smruti, Chaurasiya, Dipika, Popat, Palak, Sable, Nilesh, Agarwal, Archi, Rangarajan, Venkatesh, Joshi, Amit, Noronha, Vanita, Prabhash, Kumar, Mahantshetty, Umesh

“…We report the clinical outcomes of a randomized trial comparing prophylactic whole-pelvic nodal radiotherapy to prostate-only radiotherapy (PORT) in high-risk…”
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Systematic review and meta-analyses of intensity-modulated radiation therapy versus conventional two-dimensional and/or or three-dimensional radiotherapy in curative-intent management of head and neck squamous cell carcinoma by Gupta, Tejpal, Kannan, Sadhana, Ghosh-Laskar, Sarbani, Agarwal, Jai Prakash

“…Technological advancements in treatment planning and delivery have propelled the use of intensity-modulated radiation therapy (IMRT) in head and neck squamous…”
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Optimal adjuvant therapy in elderly glioblastoma: results from a systematic review and network meta-analysis by Kalra, Babusha, Kannan, Sadhana, Gupta, Tejpal

“…Background There exists lack of consensus worldwide regarding the most optimal adjuvant therapy regimen in elderly patients with newly-diagnosed glioblastoma…”
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Late Toxicity After Adjuvant Conventional Radiation Versus Image-Guided Intensity-Modulated Radiotherapy for Cervical Cancer (PARCER): A Randomized Controlled Trial by Chopra, Supriya, Gupta, Sudeep, Kannan, Sadhana, Dora, Tapas, Engineer, Reena, Mangaj, Akshay, Maheshwari, Amita, Shylasree, T Surappa, Ghosh, Jaya, Paul, Siji N, Phurailatpam, Reena, Charnalia, Mayuri, Alone, Mitali, Swamidas, Jamema, Mahantshetty, Umesh, Deodhar, Kedar, Kerkar, Rajendra, Shrivastava, Shyam K

“…Postoperative Adjuvant Radiation in Cervical Cancer (PARCER), a phase III randomized trial, compared late toxicity after image-guided intensity-modulated…”
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Hydroxychloroquine in the treatment of coronavirus disease 2019: Rapid updated systematic review and meta‐analysis by Gupta, Tejpal, Thakkar, Prafulla, Kalra, Babusha, Kannan, Sadhana

“…Summary Coronavirus disease 2019 (COVID‐19) caused by the novel severe acute respiratory syndrome coronavirus 2 continues to grow and spread throughout the…”
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Once-a-Week Versus Once-Every-3-Weeks Cisplatin Chemoradiation for Locally Advanced Head and Neck Cancer: A Phase III Randomized Noninferiority Trial by Noronha, Vanita, Joshi, Amit, Patil, Vijay Maruti, Agarwal, Jaiprakash, Ghosh-Laskar, Sarbani, Budrukkar, Ashwini, Murthy, Vedang, Gupta, Tejpal, D'Cruz, Anil K, Banavali, Shripad, Pai, Prathamesh S, Chaturvedi, Pankaj, Chaukar, Devendra, Pande, Nikhil, Chandrasekharan, Arun, Talreja, Vikas, Vallathol, Dilip Harindran, Mathrudev, Vijayalakshmi, Manjrekar, Aparna, Maske, Kamesh, Bhelekar, Arati Sanjay, Nawale, Kavita, Kannan, Sadhana, Gota, Vikram, Bhattacharjee, Atanu, Kane, Shubhada, Juvekar, Shashikant L, Prabhash, Kumar

“…Purpose Chemoradiation with cisplatin 100 mg/m given once every 3 weeks is the standard of care in locally advanced head and neck squamous cell cancer…”
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Systematic review and meta-analysis of randomized controlled trials comparing elective neck dissection versus sentinel lymph node biopsy in early-stage clinically node-negative oral and/or oropharyngeal squamous cell carcinoma: Evidence-base for practice and implications for research by Gupta, Tejpal, Maheshwari, Guncha, Kannan, Sadhana, Nair, Sudhir, Chaturvedi, Pankaj, Agarwal, Jai Prakash

“…•Management of node-negative neck in early-stage oral cancer has been debatable.•Nearly 20-30% of such patients harbour occult metastases in draining lymph…”
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Diagnostic performance of post-treatment FDG PET or FDG PET/CT imaging in head and neck cancer: a systematic review and meta-analysis by Gupta, Tejpal, Master, Zubin, Kannan, Sadhana, Agarwal, Jai Prakash, Ghsoh-Laskar, Sarbani, Rangarajan, Venkatesh, Murthy, Vedang, Budrukkar, Ashwini

“…Purpose Our objective was to conduct a systematic review and meta-analysis of studies assessing the diagnostic performance of 18 F-fluorodeoxyglucose positron…”
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Three-dimensional conformal radiotherapy (3D-CRT) versus intensity modulated radiation therapy (IMRT) in squamous cell carcinoma of the head and neck: A randomized controlled trial by Gupta, Tejpal, Agarwal, JaiPrakash, Jain, Sandeep, Phurailatpam, Reena, Kannan, Sadhana, Ghosh-Laskar, Sarbani, Murthy, Vedang, Budrukkar, Ashwini, Dinshaw, Ketayun, Prabhash, Kumar, Chaturvedi, Pankaj, D’Cruz, Anil

“…Abstract Purpose To compare three-dimensional conformal radiotherapy (3D-CRT) with intensity modulated radiation therapy (IMRT) in curative-intent irradiation…”
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Clinical biomarker discovery by SWATH-MS based label-free quantitative proteomics: impact of criteria for identification of differentiators and data normalization method by Narasimhan, Mythreyi, Kannan, Sadhana, Chawade, Aakash, Bhattacharjee, Atanu, Govekar, Rukmini

“…SWATH-MS has emerged as the strategy of choice for biomarker discovery due to the proteome coverage achieved in acquisition and provision to re-interrogate the…”
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A novel pro-oxidant combination of resveratrol and copper reduces transplant related toxicities in patients receiving high dose melphalan for multiple myeloma (RESCU 001) by Agarwal, Anshul, Khandelwal, Aakanksha, Pal, Kavita, Khare, Naveen Kumar, Jadhav, Vishal, Gurjar, Murarilal, Punatar, Sachin, Gokarn, Anant, Bonda, Avinash, Nayak, Lingaraj, Kannan, Sadhana, Gota, Vikram, Khattry, Navin, Mittra, Indraneel

“…Transplant related toxicity is a major therapeutic challenge. We have previously reported that the toxicity of chemotherapy is largely not directly because of…”
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Overexpression of Mcl-1L splice variant is associated with poor prognosis and chemoresistance in oral cancers by Palve, Vinayak, Mallick, Sanchita, Ghaisas, Gauri, Kannan, Sadhana, Teni, Tanuja

“…Altered expression of Mcl-1, an anti-apoptotic member of the Bcl-2 family, has been linked to the progression and outcome of a variety of malignancies. We have…”
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Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab by Patel, Usha, Pandey, Manish, Kannan, Sadhana, Samant, Tanuja A., Gera, Poonam, Mittal, Neha, Rane, Swapnil, Patil, Asawari, Noronha, Vanita, Joshi, Amit, Patil, Vijay M., Prabhash, Kumar, Mahimkar, Manoj B.

“…Background Anti-EGFR-based therapies have limited success in HNSCC patients. Predictive biomarkers are greatly needed to identify the patients likely to be…”
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Prognostic and predictive roles of cancer stem cell markers in head and neck squamous cell carcinoma patients receiving chemoradiotherapy with or without nimotuzumab by Patel, Usha, Kannan, Sadhana, Rane, Swapnil U., Mittal, Neha, Gera, Poonam, Patil, Asawari, Manna, Subhakankha, Shejwal, Vishwayani, Noronha, Vanita, Joshi, Amit, Patil, Vijay M., Prabhash, Kumar, Mahimkar, Manoj B.

“…Background Anti-EGFR-based therapies have limited success in HNSCC patients. Predictive biomarkers are needed to identify the patients most likely to benefit…”
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Late toxicity within a Phase III clinical trial of IG-IMRT in cervix cancer (PARCER): Reanalysis with time weighted adverse event reporting (MOSES) by Supriya, Chopra, Nilesh, Ranjan, Mayuri, Charnalia, Sadhana, Kannan, Reena, Engineer, Tapas, Dora, Lavanya, Gurram, Prachi, Mittal, Amita, Maheshwari, Shylasree, T.S., Shyam, Shrivastava, Sudeep, Gupta

“…•This post-hoc analysis was performed to report the impact of Image guided intensity modulated radiotherapy (IG-IMRT) and three-dimensional conformal…”
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Bortezomib and cyclophosphamide based chemo-mobilization in multiple myeloma by Bagal, Bhausaheb, Gokarn, Anant, Punatar, Sachin, Das, Shashank, Bonda, Avinash, Nayak, Lingaraj, Chichra, Akanksha, Kannan, Sadhana, Mathew, Libin J., Tembhare, Prashant, Patkar, Nikhil, Poojary, Minal, Ojha, Shashank, Subramanian, Papagudi Ganesan, Gujral, Sumeet, Khattry, Navin

“…Hematopoietic stem and progenitor cell (HSPC) mobilization regimens in multiple myeloma typically use filgrastim (GCSF) alone or combination of GCSF with…”
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Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway by Nimbalkar, Vaishnavi K., Gangar, Jeet, Shai, Saptarsi, Rane, Pallavi, Mohanta, Subham Kumar, Kannan, Sadhana, Ingle, Arvind, Mittal, Neha, Rane, Swapnil, Mahimkar, Manoj B.

“…The overexpression of Epidermal Growth Factor Receptor (EGFR) and dysregulation of its downstream effector pathways are important molecular hallmarks of oral…”
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Safety and CSF distribution of high-dose erlotinib and gefitinib in patients of non–small cell lung cancer (NSCLC) with brain metastases by Shriyan, Bharati, Patil, Deepali, Gurjar, Murari, Nookala, Manjunath, Patil, Anand, Kannan, Sadhana, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Prabhash, Kumar, Gota, Vikram

“…Purpose Patients of non–small cell lung cancer (NSCLC) with brain metastases have limited treatment options. High-dose erlotinib (HDE) and gefitinib (HDG) have…”
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SARS-CoV-2 reinfection after previous infection and vaccine breakthrough infection through the second wave of pandemic in India: An observational study by Dhumal, Sachin, Patil, Amar, More, Ashwini, Kamtalwar, Sujeet, Joshi, Amit, Gokarn, Anant, Mirgh, Sumeet, Thatikonda, Puneeth, Bhat, Prasanth, Murthy, Vedang, Chavan, Preeti, Oak, Amey, Gore, Suvarna, Bhattacharjee, Atanu, Patkar, Nikhil, Kannan, Sadhana, Shetty, Nitin, Rawat, Anjali, Achrekar, Meera, Trivedi, Bhakti, Laskar, Siddhartha, Chaturvedi, Pankaj, Badwe, Rajendra, Khattry, Navin, Gupta, Sudeep

“…•Cohort study in employees of a cancer center in India with complete follow-up.•Period of study spanning the second wave of SARS-CoV-2 pandemic in India.•Very…”
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Role of Curcumin in Reducing Toxicities Associated With Mucosal Injury Following Melphalan-Based Conditioning in Autologous Transplant Setting by Punatar, Sachin, Katti, Kritika, Rajamanickam, Deepan, Patil, Pravin, Dhakan, Chetan, Bagal, Bhausaheb, Gokarn, Anant, Bonda, Avinash, Nayak, Lingaraj, Gurjar, Murari, Kannan, Sadhana, Chiplunkar, Shubhada, Gota, Vikram, Khattry, Navin

“…Mucositis is nearly inevitable following high-dose chemotherapy. Several pro-inflammatory cytokines play a role in pathogenesis of mucositis. Curcumin inhibits…”
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