Search Results - "Kanlı,Aylin"

Changes occurring in the proteome of SH-SY5Y cells caused by fat mass and obesity associated (FTO) protein expression reveals multifaceted properties of the FTO protein by Kanlı,Aylin, Kasap,Murat, Akpınar,Gürler, Yanar,Sevinç

“…Objective: Fat mass and obesity associated (FTO) protein is an RNA-demethylase which is employed in various metabolic functions such as post-transcriptional…”
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Effect of resveratrol on chromosomal aberrations induced by doxorubicin in rat bone marrow cells by Bingöl, Günsel, Gülkaç, Mehmet Doğan, Dillioğlugil, Meltem Özlen, Polat, Fikriye, Kanli, Aylin Özön

“…•RES has anticlastogenic effect in bone marrow cells induced by DXR.•Repeated doses of RES at 25mg/kgbw has protection on DXR-induced chromosomal…”
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Effects of vitamin A on doxorubicin‐induced chromosomal aberrations in bone marrow cells of rats by Gülkaç, Mehmet Dogan, Akpinar, Gürler, Üstün, Hasan, Özön Kanli, Aylin

“…The present study was carried out to evaluate the role of vitamin A (VA) on the induction of chromosomal aberrations (CA) in rat bone marrow cells and to…”
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Comparative Proteome Analyses of Ureteropelvic Junction Obstruction and Surrounding Ureteral Tissue by Görmüş, Uzay, Kasap, Murat, Akpınar, Gürler, Tuğtepe, Halil, Kanlı, Aylin, Özel, Kerem

“…Ureteropelvic junction (UPJ) obstruction is a common problem in children, but its etiology remains unclear. In this study, the proteome profiles of the…”
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Tümör Doku Heterojenitesinin 2DE Proteomik Yaklaşımıyla Gösterilmesi by Zafer Cantürk, Gürler Akpınar, Murat Kasap, Turgay Şimşek, Aylin Kanlı

“…Amaç: Birçok hastalığın ve kanserlerin biyolojik mekanizmalarının incelenmesinde yaygın olarak kullanılan proteomik yaklaşımlar, hastalık sürecinin…”
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Protective effects of increasing vitamin E and a doses on cisplatin-induced oxidative damage to kidney tissue in rats by Dillioglugil, Meltem Ozlen, Maral Kir, Hale, Gulkac, Mehmet Dogan, Ozon Kanli, Aylin, Ozdogan, Haci Kahya, Acar, Oguz, Dillioglugil, Ozdal

“…Cisplatin (DDP, cis-diamminedichloroplatinium II) is one of the most potent chemotherapeutic antitumor drugs, but is able to generate reactive oxygen species…”
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Proteomics analysis of meclofenamic acid‐treated small cell lung carcinoma cells revealed changes in cellular energy metabolism for cancer cell survival by Yanar, Sevinc, Kasap, Murat, Kanli, Aylin, Akpinar, Gurler, Sarihan, Mehmet

“…Small cell lung carcinoma (SCLC) is a highly aggressive cancer with low survival rate. Although initial response to chemotherapy in SCLC patients is…”
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Effect of aflibercept on proliferative vitreoretinopathy: Proteomic analysis in an experimental animal model by Uslubas, Isil, Kanli, Aylin, Kasap, Murat, Akpinar, Gurler, Karabas, Levent

“…The aim of this study was to monitor inflammatory, proliferative and progressive effects of proliferative vitreoretinopathy (PVR) and aflibercept treatment in…”
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Proteomic studies associated with Parkinson's disease by Kasap, Murat, Akpinar, Gurler, Kanli, Aylin

“…Parkinson's disease (PD) is an insidious disorder affecting more than 1-2% of the population over the age of 65. Understanding the etiology of PD may create…”
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Synergistic effect of a nonsteroidal anti-inflammatory drug in combination with topotecan on small cell lung cancer cells by Yanar, Sevinc, Kanli, Aylin, Kasap, Murat, Bal Albayrak, Merve Gulsen, Eskiler, Gamze Guney, Ozkan, Asuman Deveci

“…Background The topoisomerase I inhibitor topotecan (TPT) is used in the treatment of recurrent small cell lung cancer (SCLC). However, the drug has a limited…”
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Investigation of the effect of meclofenamic acid on the proteome of LNCaP cells reveals changes in alternative polyadenylation and splicing machinery by Saglam, Busra Sahinoz, Kanli, Aylin, Yanar, Sevinc, Kasap, Murat, Akpinar, Gurler

“…Prostate cancer is the most common type of cancer among men, and there is still no definitively effective drug treatment. Thus, the search for novel drug…”
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Comparative Proteomics Analysis of Four Commonly Used Methods for Identification of Novel Plasma Membrane Proteins by Yoneten, Kubra Karaosmanoglu, Kasap, Murat, Akpinar, Gurler, Kanli, Aylin, Karaoz, Erdal

“…Plasma membrane proteins perform a variety of important tasks in the cells. These tasks can be diverse as carrying nutrients across the plasma membrane,…”
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Proteomics analysis of pleomorphic adenoma of the human parotid gland by Mutlu, Ahmet, Ozturk, Murat, Akpinar, Gurler, Kasap, Murat, Kanli, Aylin

“…The objective of this study is to perform proteomic analysis of pleomorphic adenoma (PA) in the human parotid gland (PG) with comparison of normal PG. This is…”
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Identification of differentially regulated deceitful proteins in SH‐SY5Y cells engineered with Tet‐regulated protein expression system by Kanli, Aylin, Kasap, Murat, Yoneten, Kubra K., Akpinar, Gurler, Gulkac, Mehmet Dogan

“…Tetracycline regulated protein expression in mammalian cells is a powerful tool to predict the physiological function, cellular localization, and stability of…”
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Linking a compound-heterozygous Parkin mutant (Q311R and A371T) to Parkinson's disease by using proteomic and molecular approaches by Ozgul, Sinem, Kasap, Murat, Akpinar, Gurler, Kanli, Aylin, Güzel, Nil, Karaosmanoglu, Kübra, Baykal, Ahmet Tarik, Iseri, Pervin

“…•Two inducible cell lines that expressed the WT and the mutant Parkin were created.•Biochemical properties of the WT and the mutant forms of Parkin were…”
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Exogenous Expressions of FTO Wild-Type and R316Q Mutant Proteins Caused an Increase in HNRPK Levels in 3T3-L1 Cells as Demonstrated by DIGE Analysis by Gulkac, M. Dogan, Akpinar, Gurler, Kanli, Aylin, Kasap, Murat, Guzel, Nil, Karaosmanoglu, Kubra

“…Fat mass and obesity-associated protein is an enzyme that oxidatively demethylates DNA. Although there are numerous studies regarding the catalytic function of…”
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The Demonstration of Tumor Heterogeneity using 2DE Proteomic Approach by KANLI, Aylin, ŞİMŞEK, Turgay, KASAP, Murat, AKPINAR, Gürler, CANTÜRK, Zafer

“…Objective: Proteomic approaches, have been used in monitoring the disease processes and identification of biomarkers. Biological samples used in the field of…”
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Effects of 10alpha,25-dihydroxyvitamin D3 on doxorubicin-induced chromosomal aberrations in rat bone marrow cells by Kocak, Nilufer, Ustün, Hasan, Gülkaç, Mehmet Doğan, Kanli, Aylin Ozön, Borazan, Ali, Yilmaz, Ahmet

“…The present study was carried out to evaluate the effects of 1alpha,25-dihydroxyvitamin D3 (VD) on chromosomal aberrations induced by doxorubicin (DXR). Wistar…”
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