Search Results - "Kania, Malgosia"

Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae by DAVIES, Todd A, PAGE, Malcolm G. P, WENCHI SHANG, ANDREW, Ted, KANIA, Malgosia, BUSH, Karen

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Interactions of Ceftobiprole with β-Lactamases from Molecular Classes A to D by Queenan, Anne Marie, Shang, Wenchi, Kania, Malgosia, Page, Malcolm G P, Bush, Karen

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Crystallographic and Biophysical Analysis of a Bacterial Signal Peptidase in Complex with a Lipopeptide-based Inhibitor by Paetzel, Mark, Goodall, Jonathon J, Kania, Malgosia, Dalbey, Ross E, Page, Malcolm G P

“…We report here the crystallographic and biophysical analysis of a soluble, catalytically active fragment of the Escherichia coli type I signal peptidase (SPase…”
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Structure-Activity Relationships of Different β-Lactam Antibiotics against a Soluble Form of Enterococcus faecium PBP5, a Type II Bacterial Transpeptidase by HUJER, Andrea M, KANIA, Malgosia, GERKEN, Thomas, ANDERSON, Vernon E, BUYNAK, John D, XIAOXIA GE, CASPERS, Patrick, PAGE, Malcolm G. P, RICE, Louis B, BONOMO, Robert A

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The Role of Tyrosine 150 in Catalysis of .beta.-Lactam Hydrolysis by AmpC .beta.-Lactamase from Escherichia coli Investigated by Site-Directed Mutagenesis by Dubus, Alain, Normark, Staffan, Kania, Malgosia, Page, Malcolm G. P

“…The kinetics of beta-lactam hydrolysis by wild-type AmpC beta-lactamase from Escherichia coli and three mutant proteins created by substitution of tyrosine 150…”
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Interactions of Ceftobiprole with {szligbeta}-Lactamases from Molecular Classes A to D by Queenan, Anne Marie, Shang, Wenchi, Kania, Malgosia, Page, Malcolm GP, Bush, Karen

“…The interactions of ceftobiprole with purified {szligbeta}-lactamases from molecular classes A, B, C, and D were determined and compared with those of…”
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Structure-Based Design of β-Lactamase Inhibitors. 1. Synthesis and Evaluation of Bridged Monobactams by Heinze-Krauss, Ingrid, Angehrn, Peter, Charnas, Robert L, Gubernator, Klaus, Gutknecht, Eva-Maria, Hubschwerlen, Christian, Kania, Malgosia, Oefner, Christian, Page, Malcolm G. P, Sogabe, Satoshi, Specklin, Jean-Luc, Winkler, Fritz

“…Bridged monobactams are novel, potent, mechanism-based inhibitors of class C β-lactamases, designed using X-ray crystal structures of the enzymes. They…”
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Design, Synthesis, and Evaluation of 2β-Alkenyl Penam Sulfone Acids as Inhibitors of β-Lactamases by Richter, Hans G. F, Angehrn, Peter, Hubschwerlen, Christian, Kania, Malgosia, Page, Malcolm G. P, Specklin, Jean-Luc, Winkler, Fritz K

“…A general method for synthesis of 2β-alkenyl penam sulfones has been developed. The new compounds inhibited most of the common types of β-lactamase. The level…”
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Multiple Conformations of the Acylenzyme Formed in the Hydrolysis of Methicillin by Citrobacter freundii β-Lactamase:  a Time-Resolved FTIR Spectroscopic Study by Wilkinson, Alan-Shaun, Ward, Simon, Kania, Malgosia, Page, Malcolm G. P, Wharton, Christopher W

“…Time-resolved infrared difference spectroscopy has been used to show that the carbonyl group of the acylenzyme reaction intermediate in the Citrobacter…”
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Role of asparagine 152 in catalysis of .beta.-lactam hydrolysis by Escherichia coli AmpC .beta.-lactamase studied by site-directed mutagenesis by Dubus, Alain, Normark, Staffan, Kania, Malgosia, Page, Malcolm G. P

“…The role of asparagine 152 in the catalytic mechanism of Escherichia coli AmpC beta-lactamase has been investigated by site-directed mutagenesis. The residue…”
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High-affinity receptor for interferon-gamma (IFN-gamma), a ubiquitous protein occurring in different molecular forms on human cells: blood monocytes and eleven different cell lines have the same IFN-gamma receptor protein by van Loon, A P, Ozmen, L, Fountoulakis, M, Kania, M, Haiker, M, Garotta, G

“…High-affinity receptors for human IFN-gamma were analyzed using 13 different cells, including blood monocytes. Scatchard analysis showed one high-affinity…”
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Structure and synthesis of a lipid-containing bacteriophage. Amphiphilic properties of protein IV of bacteriophage PM2 by Satake, H, Kania, M, Franklin, R M

“…Interactions between lipids and the DNA-binding protein (protein IV) purified from bacteriophage PM2 were studied in vitro. The efficiency of incorporation of…”
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Structure and Synthesis of a Lipid‐Containing Bacteriophage Studies on the Structure of the Bacteriophage PM2 Nucleocapsid by SATAKE, Haruhiko, AKUTSU, Hideo, KANIA, Malgosia, FRANKLIN, Richard M.

“…The nucleocapsid of bacteriophage PM2, prepared according to Schäfer et al. [Eur. J. Biochem. 92, 579–588 (1978)], was studied by biochemical and biophysical…”
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Structure and synthesis of a lipid-containing bacteriophage by Satake, H, Kania, M, Franklin, R.M. (Basel Univ. (Switzerland). Biozentrum. Abt. fuer Strukturbiologie)

“…Interactions between lipids and the DNA‐binding protein (protein IV) purified from bacteriophage PM2 were studied in vitro. The efficiency of incorporation of…”
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