Search Results - "Kang Seo Park"
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A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors
Published in Nature genetics (01-08-2014)“…Giuseppe Giaccone and colleagues identify a recurrent missense mutation in GTF2I in a high percentage of thymic epithelial tumors. The mutation occurs more…”
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2
Novel natural killer cell-mediated cancer immunotherapeutic activity of anisomycin against hepatocellular carcinoma cells
Published in Scientific reports (13-07-2018)“…Despite advances in the clinical management of hepatocellular carcinoma (HCC), this form of cancer remains the second leading cause of cancer-related death…”
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3
The HSP90 inhibitor, NVP-AUY922, attenuates intrinsic PI3K inhibitor resistance in KRAS-mutant non-small cell lung cancer
Published in Cancer letters (10-10-2017)“…More than 25% of non-small cell lung cancers (NSCLCs) carry mutations in KRAS, one of the most common oncogenic drivers in this disease. KRAS-mutant NSCLC…”
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4
Differences in the molecular signatures of mucosal-associated invariant T cells and conventional T cells
Published in Scientific reports (08-05-2019)“…Mucosal-associated invariant T (MAIT) cells exhibit different characteristics from those of TCRα7.2 − conventional T cells. They play important roles in…”
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5
CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance
Published in The Journal of clinical investigation (01-07-2014)“…The majority of non-small cell lung cancer (NSCLC) patients harbor EGFR-activating mutations that can be therapeutically targeted by EGFR tyrosine kinase…”
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6
HSP90 inhibitor (NVP-AUY922) enhances the anti-cancer effect of BCL-2 inhibitor (ABT-737) in small cell lung cancer expressing BCL-2
Published in Cancer letters (28-12-2017)“…Small cell lung cancer (SCLC) cannot be efficiently controlled using existing chemotherapy and radiotherapy approaches, indicating the need for new therapeutic…”
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7
Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer
Published in Journal of thoracic oncology (01-04-2014)“…There remains a significant therapeutic need for small-cell lung cancer (SCLC). We and others have reported high frequency of copy number gains in cytogenetic…”
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8
Association of ozone exposure with asthma, allergic rhinitis, and allergic sensitization
Published in Annals of allergy, asthma, & immunology (01-09-2011)“…Background Children are vulnerable to air pollution, which is known to be related to the recent increasing trend of allergic disease. Objective To investigate…”
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9
Prevalence and socioeconomic burden of diabetes mellitus in South Korean adults: a population-based study using administrative data
Published in BMC public health (20-03-2021)“…Diabetes leads to severe complications and imposes health and financial burdens on the society. However, currently existing domestic public health studies of…”
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10
Changes in sensitization rate to weed allergens in children with increased weeds pollen counts in Seoul metropolitan area
Published in Journal of Korean medical science (01-04-2012)“…The prevalence of allergic diseases in children has increased for several decades. We evaluated the correlation between pollen count of weeds and their…”
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11
The revised edition of korean calendar for allergenic pollens
Published in Allergy, asthma & immunology research (01-01-2012)“…The old calendar of pollens did not reflect current pollen distribution and concentrations that can be influenced by changes of weather and environment of each…”
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Transglutaminase 2 as an independent prognostic marker for survival of patients with non-adenocarcinoma subtype of non-small cell lung cancer
Published in Molecular cancer (24-09-2011)“…Expression of transglutaminase 2 (TGase 2) is related to invasion and resistance to chemotherapeutic agents in several cancer cells. However, there has been…”
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13
Breastfeeding Might Have Protective Effects on Atopy in Children With the CD14C-159T CT/CC Genotype
Published in Allergy, asthma & immunology research (01-07-2013)“…Breastfeeding is widely recommended to reduce risk of sensitization, eczema and asthma. However, the role of breastfeeding in prevention of allergic diseases…”
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14
Comparison of the Efficacy and Safety of Insulin Detemir Administered Once Daily According to Two Titration Algorithms (3-0-3 and 2-4-6-8) in Patients with Type 2 Diabetes Mellitus
Published in Endocrinology and metabolism (Seoul) (31-03-2020)“…Background: This study was conducted to compare glycaemic control with insulin detemir administered according to two titration algorithms (3-0-3 and 2-4-6-8)…”
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Depletion of nucleophosmin via transglutaminase 2 cross-linking increases drug resistance in cancer cells
Published in Cancer letters (18-02-2009)“…Abstract It has been suggested that nucleophosmin has an anti-apoptotic function via Bax binding. We found that nucleophosmin is a substrate of…”
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16
High cripto-1 and low miR-205 expression levels as prognostic markers in early stage non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-02-2018)“…•We evaluated Cripto-1 and miR-205 expression by IHC and qPCR, respectively, in 265 resected NSCLC.•We demonstrated that high cripto-1 expression correlates…”
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Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity
Published in The Journal of pathology (01-11-2020)“…Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a…”
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A phase 4 randomized active-controlled clinical study to compare the efficacy and safety of sustained-release pregabalin with immediate-release pregabalin in type 2 diabetic patients with peripheral neuropathic pain
Published in Journal of diabetes and its complications (01-08-2024)“…The objective of this study was to demonstrate that sustained-release (SR) pregabalin is non-inferior to immediate-release (IR) pregabalin in attenuating…”
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Clinical Implications of Using Post-Challenge Plasma Glucose Levels for Early Diagnosis of Type 2 Diabetes Mellitus in Older Individuals
Published in Diabetes & metabolism journal (30-04-2018)“…Background: The aim of this study was to explore the differences in the clinical characteristics and diagnostic rates of diabetes mellitus (DM) according to…”
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HSP90 inhibitor, AUY922, debilitates intrinsic and acquired lapatinib-resistant HER2-positive gastric cancer cells
Published in BMB reports (31-12-2018)“…Human epidermal growth factor receptor 2 (HER2) inhibitors, such as trastuzumab and lapatinib are used to treat HER2-positive breast and gastric cancers…”
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