Search Results - "Kang, Yuqi"

ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment by Li, Na, Kang, Yuqi, Wang, Lingling, Huff, Sarah, Tang, Rachel, Hui, Hui, Agrawal, Kriti, Gonzalez, Gwendolyn Michelle, Wang, Yinsheng, Patel, Sandip Pravin, Rana, Tariq M.

“…Although immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, many patients do not respond or develop resistance to ICB…”
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A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities by Chan, Marina, Kang, Yuqi, Osborne, Shannon, Zager, Michael, Gujral, Taranjit S

“…Cytokines and chemokines are secreted proteins that regulate various biological processes, such as inflammation, immune response, and cell differentiation…”
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HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1 by Zhang, Qiong, Kang, Yuqi, Wang, Shaobo, Gonzalez, Gwendolyn Michelle, Li, Wanyu, Hui, Hui, Wang, Yinsheng, Rana, Tariq M.

“…N 6 ,2′- O -dimethyladenosine (m 6 Am) is an abundant RNA modification located adjacent to the 5′-end of the mRNA 7-methylguanosine (m 7 G) cap structure. m 6…”
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Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation by Olson, Annabel T, Kang, Yuqi, Ladha, Anushka M, Zhu, Songli, Lim, Chuan Bian, Nabet, Behnam, Lagunoff, Michael, Gujral, Taranjit S, Geballe, Adam P

“…Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in…”
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Atypical Hemolytic Uremic Syndrome-Associated FHR1 Isoform FHR1B Enhances Complement Activation and Inflammation by Xu, Boyang, Kang, Yuqi, Du, Yujing, Guo, Weiyi, Zhu, Li, Zhang, Hong

“…Atypical hemolytic uremic syndrome (aHUS) is a rare but severe type of thrombotic microangiopathy that is triggered by the abnormal activation of the…”
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Deep neural network modeling identifies biomarkers of response to immune-checkpoint therapy by Kang, Yuqi, Vijay, Siddharth, Gujral, Taranjit S.

“…Immunotherapy has shown significant promise as a treatment for cancer, such as lung cancer and melanoma. However, only 10%–30% of the patients respond to…”
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Hydrogen Sulfide Demonstrates Promising Antitumor Efficacy in Gastric Carcinoma by Targeting MGAT5 by Wang, Rui, Fan, Qilin, Zhang, Junjie, Zhang, Xunan, Kang, Yuqi, Wang, Zhirong

“…Mannosyl (alpha-1,6-)-Glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (MGAT5) is exclusively expressed in gastric carcinoma, and plays an essential role…”
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134 Mesangial cells derived complement factor H inhibits complement activation and inflammation in IgA Nephropathy by Li, Yebei, Kang, Yuqi, Shi, Sufang, Zhu, Li, Zhang, Hong

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KIAA1429/VIRMA promotes breast cancer progression by m 6 A-dependent cytosolic HAS2 stabilization by Li, Na, Zhu, Zhouting, Deng, Yufei, Tang, Rachel, Hui, Hui, Kang, Yuqi, Rana, Tariq M

“…N -methyladenosine (m A), the most abundant internal modification in eukaryotic mRNA, plays important roles in many physiological and pathological processes,…”
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Longitudinal correlates of bullying victimization among Chinese early adolescents: A cross-lagged panel network analysis by Li, Yuan, Kang, Yuqi, Zhu, Li, Yuan, Mengyuan, Li, Yonghan, Xu, Baoyu, Zhang, Xueying, Wang, Gengfu, Su, Puyu

“…Bullying victimization is a major public health issue often faced by adolescents. This highlights the need to identify the relevant risk factors to inform…”
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KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization by Li, Na, Zhu, Zhouting, Deng, Yufei, Tang, Rachel, Hui, Hui, Kang, Yuqi, Rana, Tariq M

“…N6‐methyladenosine (m6A), the most abundant internal modification in eukaryotic mRNA, plays important roles in many physiological and pathological processes,…”
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A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities by Chan, Marina, Kang, Yuqi, Osborne, Shannon, Zager, Michael, Gujral, Taranjit S

“…Cytokines and chemokines are secreted proteins that regulate various biological processes, such as inflammation, immune response, and cell differentiation…”
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Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy by Kang, Yuqi, Xu, Boyang, Shi, Sufang, Zhou, Xujie, Chen, Pei, Liu, Lijun, Li, Yebei, Leng, Yueqi, Lv, Jicheng, Zhu, Li, Zhang, Hong

“…IgA nephropathy is the most common primary GN worldwide, with dominant deposition of IgA and co-deposits of complement component 3 (C3). Phenotypes and…”
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Abstract 616: Integrating organotypic tissue slices and polypharmacology-based screening to map the toxicity landscape of kinase inhibitors by Kang, Yuqi, Chan, Marina, Zhu, Songli, Gujral, Taranjit S.

“…Abstract Protein kinases play important role in the regulation of various biological processes, and their malfunction and dysregulation are intricately linked…”
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m 6 A RNA methyltransferases METTL3/14 regulate immune responses to anti-PD-1 therapy by Wang, Lingling, Hui, Hui, Agrawal, Kriti, Kang, Yuqi, Li, Na, Tang, Rachel, Yuan, Jiajun, Rana, Tariq M

“…An impressive clinical success has been observed in treating a variety of cancers using immunotherapy with programmed cell death-1 (PD-1) checkpoint blockade…”
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m6A RNA methyltransferases METTL3/14 regulate immune responses to anti‐PD‐1 therapy by Wang, Lingling, Hui, Hui, Agrawal, Kriti, Kang, Yuqi, Li, Na, Tang, Rachel, Yuan, Jiajun, Rana, Tariq M

“…An impressive clinical success has been observed in treating a variety of cancers using immunotherapy with programmed cell death‐1 (PD‐1) checkpoint blockade…”
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Machine learning based suicidality risk prediction in early adolescence by Wen, Xue, Kang, Yuqi, Li, Yuan, Yuan, Mengyuan, Li, Yonghan, Xu, Baoyu, Su, Puyu, Wang, Gengfu

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Subtype and Site Specific-Induced Metabolic Vulnerabilities in Prostate Cancer by Mossa, Federica, Robesti, Daniele, Sumankalai, Ramachandran, Corey, Eva, Titus, Mark, Kang, Yuqi, Zhang, Jianhua, Briganti, Alberto, Montorsi, Francesco, Vellano, Christopher P, Marszalek, Joseph R, Frigo, Daniel E, Logothetis, Christopher J, Gujral, Taranjit S, Dondossola, Eleonora

“…Aberrant metabolic functions play a crucial role in prostate cancer progression and lethality. Currently, limited knowledge is available on subtype-specific…”
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KIAA1429/VIRMA promotes breast cancer progression by m6 A-dependent cytosolic HAS2 stabilization by Li, Na, Zhu, Zhouting, Deng, Yufei, Tang, Rachel, Hui, Hui, Kang, Yuqi, Rana, Tariq M

“…N6 -methyladenosine (m6 A), the most abundant internal modification in eukaryotic mRNA, plays important roles in many physiological and pathological processes,…”
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Fatty-acid receptor CD36 functions as a hydrogen sulfide-targeted receptor with its Cys333-Cys272 disulfide bond serving as a specific molecular switch to accelerate gastric cancer metastasis by Wang, Rui, Tao, Beibei, Fan, Qilin, Wang, Shengyue, Chen, Li, Zhang, Junjie, Hao, Yinfang, Dong, Shuang, Wang, Zhe, Wang, Wei, Cai, Yixi, Li, Xutong, Bao, Tuvshin, Wang, Xiaohui, Qiu, Xiaoming, Wang, Kekun, Mo, Xinyu, Kang, Yuqi, Wang, Zhirong

“…Hydrogen Sulfide (H2S), a third member of gasotransmitter family along with nitric oxide (NO) and carbon monoxide (CO), exerts a wide range of cellular and…”
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