Search Results - "Kang, Xiongbin"
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phasebook: haplotype-aware de novo assembly of diploid genomes from long reads
Published in Genome Biology (27-10-2021)“…Haplotype-aware diploid genome assembly is crucial in genomics, precision medicine, and many other disciplines. Long-read sequencing technologies have greatly…”
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Strainline: full-length de novo viral haplotype reconstruction from noisy long reads
Published in Genome Biology (20-01-2022)“…Haplotype-resolved de novo assembly of highly diverse virus genomes is critical in prevention, control and treatment of viral diseases. Current methods either…”
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VeChat: correcting errors in long reads using variation graphs
Published in Nature communications (04-11-2022)“…Error correction is the canonical first step in long-read sequencing data analysis. Current self-correction methods, however, are affected by consensus…”
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HyLight: Strain aware assembly of low coverage metagenomes
Published in Nature communications (07-10-2024)“…Different strains of identical species can vary substantially in terms of their spectrum of biomedically relevant phenotypes. Reconstructing the genomes of…”
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Hybrid-hybrid correction of errors in long reads with HERO
Published in Genome Biology (01-12-2023)“…Although generally superior, hybrid approaches for correcting errors in third-generation sequencing (TGS) reads, using next-generation sequencing (NGS) reads,…”
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Enhancing Long-Read-Based Strain-Aware Metagenome Assembly
Published in Frontiers in genetics (13-05-2022)“…Microbial communities are usually highly diverse and often involve multiple strains from the participating species due to the rapid evolution of…”
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Reprocessing 16S rRNA Gene Amplicon Sequencing Studies: (Meta)Data Issues, Robustness, and Reproducibility
Published in Frontiers in cellular and infection microbiology (21-10-2021)“…High-throughput sequencing technology provides an efficient method for evaluating microbial ecology. Different bioinformatics pipelines can be used to convert…”
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An Advanced Model to Precisely Estimate the Cell-Free Fetal DNA Concentration in Maternal Plasma
Published in PloS one (23-09-2016)“…With the speedy development of sequencing technologies, noninvasive prenatal testing (NIPT) has been widely applied in clinical practice for testing for fetal…”
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StrainXpress: strain aware metagenome assembly from short reads
Published in Nucleic acids research (23-09-2022)“…Abstract Next-generation sequencing–based metagenomics has enabled to identify microorganisms in characteristic habitats without the need for lengthy…”
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Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks
Published in Nature machine intelligence (01-02-2023)“…Diseases that have a complex genetic architecture tend to suffer from considerable amounts of genetic variants that, although playing a role in the disease,…”
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Complete mitochondrial genome of the American flamingo, Phoenicopterus ruber (Phoenicopteriformes, Phoenicopteridae)
Published in Mitochondrial DNA. Part A. DNA mapping, sequencing, and analysis (02-09-2016)“…The American flamingo, Phoenicopterus ruber (P. ruber), is a large species of flamingo closely related to the greater flamingo and Chilean flamingo. In this…”
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Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate non‐invasive prenatal testing
Published in Prenatal diagnosis (01-12-2017)“…Objective The purpose of this study were to develop a methodology of isolating fetal cells from maternal blood and use deep sequence demonstrating the promise…”
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Complete mitochondrial genome of Drosophila albomicans
Published in Mitochondrial DNA. Part A. DNA mapping, sequencing, and analysis (02-09-2016)“…Drosophila albomicans has been widely used as an important animal model for chromosome evolution. In this study, the mitochondrial genome sequence of this…”
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