Search Results - "Kang, Un‐Beom"

Leucine‐rich repeat kinase 2 and Parkinson's disease by Kang, Un‐Beom, Marto, Jarrod A.

“…Leucine‐rich repeat kinase 2 (LRRK2) is a large multidomain protein that is expressed in many tissues and participates in numerous biological pathways…”
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Interrogating the hidden phosphoproteome by Kang, Un‐Beom, Alexander, William M., Marto, Jarrod A.

“…Postgenomic studies continue to highlight the potential clinical importance of protein phosphorylation signaling pathways in drug discovery. Unfortunately, the…”
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Quantitative Analysis of mTRAQ-Labeled Proteome Using Full MS Scans by Kang, Un-Beom, Yeom, Jeonghun, Kim, Hoguen, Lee, Cheolju

“…Proteomic techniques are mostly used these days to identify proteins in a biological sample. Quantification of the differences between two or more…”
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Comparative profiling by data-independent acquisition mass spectrometry reveals featured plasma proteins in breast cancer: a pilot study by Yoon, Kyung-Hwak, Chu, Hyosub, Kim, Hyeonji, Huh, Sunghyun, Kim, Eun-Kyu, Kang, Un-Beom, Shin, Hee-Chul

“…Breast cancer is known to be influenced by genetic and environmental factors, and several susceptibility genes have been discovered. Still, the majority of…”
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Profiling of vitreous proteomes from proliferative diabetic retinopathy and nondiabetic patients by Kim, Taeoh, Kim, Sang Jin, Kim, Kyunggon, Kang, Un-Beom, Lee, Cheolju, Park, Kyong Soo, Yu, Hyeong Gon, Kim, Youngsoo

“…Diabetes can lead to serious microvascular complications like proliferative diabetic retinopathy (PDR), which is the leading cause of blindness in adults. The…”
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Association Between the C4 Binding Protein Level and White Matter Integrity in Major Depressive Disorder by Park, Jihoon, Kang, Youbin, Han, Kyu-Man, Tae, Woo-Suk, Kang, Un-Beom, Chu, Hyosub, Ham, Byung-Joo

“…Objective Considerable evidence suggests that neuroinflammation plays an important role in the pathophysiology of major depressive disorder (MDD). However, the…”
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Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation by Joo, Yoo Jin, Kim, Jin-Ha, Kang, Un-Beom, Yu, Myeong-Hee, Kim, Joon

“…Gcn4p is a well‐characterized bZIP transcription factor that activates more than 500 genes encoding amino acids and purine biosynthesis enzymes, and many…”
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Proteomic Interrogation in Cancer Biomarker by Kang, Un-Beom

“…Biomarkers factor into the diagnosis and treatment of almost every patient with cancer. The innovation in proteomics follows improvement of mass spectrometry…”
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Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker by Kang, Un-Beom, Ahn, Younghee, Lee, Jong Won, Kim, Yong-Hak, Kim, Joon, Yu, Myeong-Hee, Noh, Dong-Young, Lee, Cheolju

“…Breast cancer is one of the leading causes of women's death worldwide. It is important to discover a reliable biomarker for the detection of breast cancer…”
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Comparative profiling of plasma proteome from breast cancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers by Suh, Eui Jin, Kabir, Mohammad Humayun, Kang, Un-Beom, Lee, Jong Won, Yu, Jonghan, Noh, Dong-Young, Lee, Cheolju

“…Breast cancer is the most common cancer in women worldwide. It is necessary to identify biomarkers for early detection, to make accurate prognoses, and to…”
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Identification of circulating endorepellin LG3 fragment: Potential use as a serological biomarker for breast cancer by Chang, Jong Wook, Kang, Un-Beom, Kim, Dong Hyun, Yi, Jae Kyo, Lee, Jong Won, Noh, Dong-Young, Lee, Cheolju, Yu, Myeong-Hee

“…Comparative proteome analysis was performed on the cultured media of human nontumor and malignant breast cell lines, Hs578Bst and Hs578T, respectively, in…”
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Nogo-A regulates myogenesis via interacting with Filamin-C by Park, SunYoung, Park, Ji-Hwan, Kang, Un-Beom, Choi, Seong-Kyoon, Elfadl, Ahmed, Ullah, H. M. Arif, Chung, Myung-Jin, Son, Ji-Yoon, Yun, Hyun Ho, Park, Jae-Min, Yim, Jae-hyuk, Jung, Seung-Jun, Kim, Sang-Hyup, Choi, Young-Chul, Kim, Dae-Seong, Shin, Jin-Hong, Park, Jin-Sung, Hur, Keun, Lee, Sang-Han, Lee, Eun-Joo, Hwang, Daehee, Jeong, Kyu-Shik

“…Among the three isoforms encoded by Rtn4 , Nogo-A has been intensely investigated as a central nervous system inhibitor. Although Nogo-A expression is…”
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Direct Analysis of Phosphorylation Sites on the Rpb1 C-Terminal Domain of RNA Polymerase II by Suh, Hyunsuk, Ficarro, Scott B., Kang, Un-Beom, Chun, Yujin, Marto, Jarrod A., Buratowski, Stephen

“…Dynamic interactions between RNA polymerase II and various mRNA-processing and chromatin-modifying enzymes are mediated by the changing phosphorylation pattern…”
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Novel Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Uncovered by Data-Independent Acquisition Mass Spectrometry by Huh, Sunghyun, Kang, Chaewon, Park, Ji Eun, Nam, Dowoon, Kim, Se Ik, Seol, Aeran, Choi, Kyerim, Hwang, Daehee, Yu, Myeong-Hee, Chung, Hyun Hoon, Lee, Sang-Won, Kang, Un-Beom

“…High-grade serous ovarian cancer (HGSOC) represents the major histological type of ovarian cancer, and the lack of effective screening tools and early…”
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Probing the local conformational change of α1‐antitrypsin by Baek, Je‐Hyun, Im, Hana, Kang, Un‐Beom, Seong, Ki Moon, Lee, Cheolju, Kim, Joon, Yu, Myeong‐Hee

“…The native form of serpins (serine protease inhibitors) is a metastable conformation, which converts into a more stable form upon complex formation with a…”
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Proteomic analysis of γ-butyrolactone-treated mouse thalamus reveals dysregulated proteins upon absence seizure by Ryu, Myung-Jeom, Kim, Daesoo, Kang, Un-Beom, Kim, Joon, Shin, Hee-Sup, Lee, Cheolju, Yu, Myeong-Hee

“…Absence seizure has been of interest because the symptom is related to sensory processing. However, the mechanism that causes the disease is not understood…”
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Common Repository of FBS Proteins (cRFP) To Be Added to a Search Database for Mass Spectrometric Analysis of Cell Secretome by Shin, Jihye, Kwon, Yumi, Lee, Seonjeong, Na, Seungjin, Hong, Eun Young, Ju, Shinyeong, Jung, Hyun-Gyo, Kaushal, Prashant, Shin, Sungho, Back, Ji Hyun, Choi, Seon Young, Kim, Eun Hee, Lee, Su Jin, Park, Yae Eun, Ahn, Hee-Sung, Ahn, Younghee, Kabir, Mohammad Humayun, Park, Seong-Jun, Yang, Won Suk, Yeom, Jeonghun, Bang, Oh Young, Ha, Chul-Won, Lee, Jin-Won, Kang, Un-Beom, Kim, Hye-Jung, Park, Kang-Sik, Lee, J. Eugene, Lee, Ji Eun, Kim, Jin Young, Kim, Kwang Pyo, Kim, Youngsoo, Hirano, Hisashi, Yi, Eugene C, Cho, Je-Yoel, Paek, Eunok, Lee, Cheolju

“…We propose to use cRFP (common Repository of FBS Proteins) in the MS (mass spectrometry) raw data search of cell secretomes. cRFP is a small supplementary…”
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A Validation Study of a Multiple Reaction Monitoring-Based Proteomic Assay to Diagnose Breast Cancer by Kim, Yumi, Kang, Un-Beom, Kim, Sungsoo, Lee, Han-Byoel, Moon, Hyeong-Gon, Han, Wonshik, Noh, Dong-Young

“…Currently, the standard screening tool for breast cancer is screening mammography. There have been many efforts to develop a blood-based diagnostic assay for…”
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Comparative profiling of plasma proteome from breast cancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers by Suh, Eui Jin, Kabir, Mohammad Humayun, Kang, Un-Beom, Lee, Jong Won, Yu, Jonghan, Noh, Dong-Young, Lee, Cheolju

“…Breast cancer is the most common cancer in women worldwide. It is necessary to identify biomarkers for early detection, to make accurate prognoses, and to…”
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Development and Validation of a Novel Plasma Protein Signature for Breast Cancer Diagnosis by Using Multiple Reaction Monitoring-based Mass Spectrometry by Lee, Han-Byoel, Kang, Un-Beom, Moon, Hyeong-Gon, Lee, Jiwoo, Lee, Kyung-Min, Yi, Minju, Park, Yong Sun, Lee, Jong Won, Yu, Jong-Han, Choi, Seung Ho, Cho, Sang Heon, Lee, Cheolju, Han, Wonshik, Noh, Dong-Young

“…We aimed to develop a plasma protein signature for breast cancer diagnosis by using multiple reaction monitoring (MRM)-based mass spectrometry. Based on our…”
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