Search Results - "Kang, Sumin"

Mitochondrial metabolism-mediated redox regulation in cancer progression by Boese, Austin C., Kang, Sumin

“…Cancer cells display abnormal metabolic activity as a result of activated oncogenes and loss of tumor suppressor genes. The Warburg Effect is a common…”
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Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1 by Pan, Chaoyun, Kang, JiHoon, Hwang, Jung Seok, Li, Jie, Boese, Austin C., Wang, Xu, Yang, Likun, Boggon, Titus J., Chen, Georgia Z., Saba, Nabil F., Shin, Dong M., Magliocca, Kelly R., Jin, Lingtao, Kang, Sumin

“…Agonists of glucocorticoid receptor (GR) are frequently given to cancer patients with platinum-containing chemotherapy to reduce inflammation, but how GR…”
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The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer by Jin, Lingtao, Chun, Jaemoo, Pan, Chaoyun, Kumar, Avi, Zhang, Guojing, Ha, Youna, Li, Dan, Alesi, Gina N., Kang, Yibin, Zhou, Lu, Yu, Wen-Mei, Magliocca, Kelly R., Khuri, Fadlo R., Qu, Cheng-Kui, Metallo, Christian, Owonikoko, Taofeek K., Kang, Sumin

“…Loss of LKB1 is associated with increased metastasis and poor prognosis in lung cancer, but the development of targeted agents is in its infancy. Here we…”
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Social Type-Aware Navigation Framework for Mobile Robots in Human-Shared Environments by Kang, Sumin, Yang, Sungwoo, Kwak, Daewon, Jargalbaatar, Yura, Kim, Donghan

“…As robots become increasingly common in human-populated environments, they must be perceived as social beings and behave socially. People try to preserve their…”
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Transformable Gaussian Reward Function for Socially Aware Navigation Using Deep Reinforcement Learning by Kim, Jinyeob, Kang, Sumin, Yang, Sungwoo, Kim, Beomjoon, Yura, Jargalbaatar, Kim, Donghan

“…Robot navigation has transitioned from avoiding static obstacles to adopting socially aware navigation strategies for coexisting with humans. Consequently,…”
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Exploring the multifaceted role of ginkgolides and bilobalide from Ginkgo biloba in mitigating metabolic disorders by Kim, Hayoon, Kang, Sumin, Go, Gwang-woong

“…The ancient Ginkgo biloba tree grows across various regions, with distinctive leaves emitting a unique fragrance. Its extract contains flavonoids, organic…”
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DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling by Li, Jie, Pan, Chaoyun, Boese, Austin C, Kang, JiHoon, Umano, Anna D, Magliocca, Kelly R, Yang, Wenqing, Zhang, Yu, Lonial, Sagar, Jin, Lingtao, Kang, Sumin

“…Although platinum compounds are the first-line treatment for ovarian cancer, the majority of patients relapse and develop resistance to treatment. However, the…”
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Graphene-enabled laser lift-off for ultrathin displays by Kang, Sumin, Chang, Jaehyeock, Lim, Jaeseung, Kim, Dong Jun, Kim, Taek-Soo, Choi, Kyung Cheol, Lee, Jae Hak, Kim, Seungman

“…Laser lift-off (LLO) of ultrathin polyimide (PI) films is important in the manufacturing of ultrathin displays. However, conventional LLO technologies face…”
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Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth by Jin, Lingtao, Li, Dan, Alesi, Gina N., Fan, Jun, Kang, Hee-Bum, Lu, Zhou, Boggon, Titus J., Jin, Peng, Yi, Hong, Wright, Elizabeth R., Duong, Duc, Seyfried, Nicholas T., Egnatchik, Robert, DeBerardinis, Ralph J., Magliocca, Kelly R., He, Chuan, Arellano, Martha L., Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin

“…How mitochondrial glutaminolysis contributes to redox homeostasis in cancer cells remains unclear. Here we report that the mitochondrial enzyme glutamate…”
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Selective Targeting of Distinct Active Site Nucleophiles by Irreversible Src-Family Kinase Inhibitors by Gushwa, Nathan N, Kang, Sumin, Chen, Jing, Taunton, Jack

“…Src-family tyrosine kinases play pivotal roles in human physiology and disease, and several drugs that target members of this family are in clinical use. None…”
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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation by Jin, Lingtao, Chun, Jaemoo, Pan, Chaoyun, Li, Dan, Lin, Ruiting, Alesi, Gina N., Wang, Xu, Kang, Hee-Bum, Song, Lina, Wang, Dongsheng, Zhang, Guojing, Fan, Jun, Boggon, Titus J., Zhou, Lu, Kowalski, Jeanne, Qu, Cheng-Kui, Steuer, Conor E., Chen, Georgia Z., Saba, Nabil F., Boise, Lawrence H., Owonikoko, Taofeek K., Khuri, Fadlo R., Magliocca, Kelly R., Shin, Dong M., Lonial, Sagar, Kang, Sumin

“…Platinum-based chemotherapeutics represent a mainstay of cancer therapy, but resistance limits their curative potential. Through a kinome RNAi screen, we…”
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Black beans (Glycine max (L.) Merrill) included in a multi-grain rice reduce total cholesterol and enhance antioxidant capacity in high-fat diet-induced obese mice by Kim, Hayoon, Kang, Sumin, Go, Gwang-woong

“…This study investigated the effects of black bean (BB) supplementation on the growth performance, lipid metabolism, and antioxidant capacity of high-fat…”
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Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex by Fan, Jun, Shan, Changliang, Kang, Hee-Bum, Elf, Shannon, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chen, Huaibin, Mohammadi, Moosa, Britton, Laura-Mae P., Garcia, Benjamin A., Alečković, Maša, Kang, Yibin, Kaluz, Stefan, Devi, Narra, Van Meir, Erwin G., Hitosugi, Taro, Seo, Jae Ho, Lonial, Sagar, Gaddh, Manila, Arellano, Martha, Khoury, Hanna J., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing

“…Mitochondrial pyruvate dehydrogenase complex (PDC) is crucial for glucose homeostasis in mammalian cells. The current understanding of PDC regulation involves…”
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Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth by Hitosugi, Taro, Zhou, Lu, Elf, Shannon, Fan, Jun, Kang, Hee-Bum, Seo, Jae Ho, Shan, Changliang, Dai, Qing, Zhang, Liang, Xie, Jianxin, Gu, Ting-Lei, Jin, Peng, Alečković, Masa, LeRoy, Gary, Kang, Yibin, Sudderth, Jessica A., DeBerardinis, Ralph J., Luan, Chi-Hao, Chen, Georgia Z., Muller, Susan, Shin, Dong M., Owonikoko, Taofeek K., Lonial, Sagar, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Ye, Keqiang, Boggon, Titus J., Kang, Sumin, He, Chuan, Chen, Jing

“…It is unclear how cancer cells coordinate glycolysis and biosynthesis to support rapidly growing tumors. We found that the glycolytic enzyme phosphoglycerate…”
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Simple Protein Analysis by Droplet Paper Spray Ionization Mass Spectrometry with Polyolefin Silica-Based Paper by An, Sung Jun, Kal, Youngjoo, Jeong, Minjoo, Kang, Sumin, Kwak, Byeongho, Kim, Hyunsoo, Ryu, Shihyeon, Cha, Sangwon

“…Paper spray ionization mass spectrometry (PSI MS) has emerged as a notable method for the rapid analysis of biological samples. However, the typical…”
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Ambivalence towards pork belly: exploring its significance and contradictions from the perspectives of the food industry and nutritional science by Kang, Sumin, Gang, Gyoungok, Go, Gwang-woong

“…Pork is the most consumed meat in South Korea, and pork belly is the preferred cut. However, pork production cannot meet the demand, leading to a heavy…”
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Rottlerin suppresses lipid accumulation by inhibiting de novo lipogenesis and adipogenesis via LRP6/mTOR/SREBP1C in 3T3-L1 adipocytes by Kim, Yejin, Kim, Hyun Kyung, Kang, Sumin, Kim, Hayoon, Go, Gwang-woong

“…Rottlerin is isolated from Mallotus japonicus , a plant rich in polyphenols. Rottlerin is a selective PKCδ-inhibitor and is also known as an uncoupler of…”
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Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD+ Redox Homeostasis in Cancer Cells by Fan, Jun, Hitosugi, Taro, Chung, Tae-Wook, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Chen, Georgia Z., Boggon, Titus J., Lonial, Sagar, Khuri, Fadlo R., Kang, Sumin, Chen, Jing

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism by Hitosugi, Taro, Fan, Jun, Chung, Tae-Wook, Lythgoe, Katherine, Wang, Xu, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Roesel, Johannes L., Chen, Georgia Z., Boggon, Titus J., Lonial, Sagar, Fu, Haian, Khuri, Fadlo R., Kang, Sumin, Chen, Jing

“…Many tumor cells rely on aerobic glycolysis instead of oxidative phosphorylation for their continued proliferation and survival. Myc and HIF-1 are believed to…”
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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth by Hitosugi, Taro, Kang, Sumin, Vander Heiden, Matthew G, Chung, Tae-Wook, Elf, Shannon, Lythgoe, Katherine, Dong, Shaozhong, Lonial, Sagar, Wang, Xu, Chen, Georgia Z, Xie, Jianxin, Gu, Ting-Lei, Polakiewicz, Roberto D, Roesel, Johannes L, Boggon, Titus J, Khuri, Fadlo R, Gilliland, D Gary, Cantley, Lewis C, Kaufman, Jonathan, Chen, Jing

“…The Warburg effect describes a pro-oncogenic metabolism switch such that cancer cells take up more glucose than normal tissue and favor incomplete oxidation of…”
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