Search Results - "Kang, Phillip H"

Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis by Luzina, Irina G, Lockatell, Virginia, Hyun, Sang W, Kopach, Pavel, Kang, Phillip H, Noor, Zahid, Liu, Anguo, Lillehoj, Erik P, Lee, Chunsik, Miranda-Ribera, Alba, Todd, Nevins W, Goldblum, Simeon E, Atamas, Sergei P

“…Idiopathic pulmonary fibrosis (IPF) poses challenges to understanding its underlying cellular and molecular mechanisms and the development of better therapies…”
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Angiomotin links ROCK and YAP signaling in mechanosensitive differentiation of neural stem cells by Kang, Phillip H, Schaffer, David V, Kumar, Sanjay

“…Mechanical cues regulate the function of a broad range of stem cells in culture and in tissue. For example, soft substrates promote the neuronal…”
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Matrix degradation: Making way for neural stemness by Kang, Phillip H, Kumar, Sanjay, Schaffer, David V

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Interleukin-33 potentiates bleomycin-induced lung injury by Luzina, Irina G, Kopach, Pavel, Lockatell, Virginia, Kang, Phillip H, Nagarsekar, Ashish, Burke, Allen P, Hasday, Jeffrey D, Todd, Nevins W, Atamas, Sergei P

“…The mechanisms of interstitial lung disease (ILD) remain incompletely understood, although recent observations have suggested an important contribution by…”
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Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion by Luzina, Irina G, Pickering, Edward M, Kopach, Pavel, Kang, Phillip H, Lockatell, Virginia, Todd, Nevins W, Papadimitriou, John C, McKenzie, Andrew N J, Atamas, Sergei P

“…Expression of IL-33 is elevated in patients with pulmonary diseases, and full-length (not proteolytically processed) IL-33 is the predominant form in the lungs…”
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Full-length IL-33 augments pulmonary fibrosis in an ST2- and Th2-independent, non-transcriptomic fashion by Luzina, Irina G., Lockatell, Virginia, Courneya, Jean-Paul, Mei, Zhongcheng, Fishelevich, Rita, Kopach, Pavel, Pickering, Edward M., Kang, Phillip H., Krupnick, Alexander S., Todd, Nevins W., Vogel, Stefanie N., Atamas, Sergei P.

“…•Genetic depletion or deletion of IL-33, or depletion of ST2, inhibited lung fibrosis.•Full-length IL-33 enhanced the profibrotic effect of bleomycin…”
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Natural production and functional effects of alternatively spliced interleukin-4 protein in asthma by Luzina, Irina G., Lockatell, Virginia, Lavania, Sachin, Pickering, Edward M., Kang, Phillip H., Bashkatova, Yulia N., Andreev, Sergey M., Atamas, Sergei P.

“…► An alternative splice variant of IL-4 protein termed IL-4δ2 is naturally produced. ► IL-4δ2 protein is produced by T cells from asthma patients but not from…”
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eEF1A1 mediates mechanosensitive differentiation of adult neural stem cells by Lopez, Paola A., Kang, Phillip H., Kumar, Sanjay, Schaffer, David

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Making way for neural stemness by Kang, Phillip H., Kumar, Sanjay, Schaffer, David V.

“…The influence of matrix stiffness and degradation on neural progenitor cell stemness was investigated in a three-dimensional culture system, highlighting the…”
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Novel biomaterials to study neural stem cell mechanobiology and improve cell-replacement therapies by Kang, Phillip H., Kumar, Sanjay, Schaffer, David V.

“…Neural stem cells (NSCs) are a valuable cell source for tissue engineering, regenerative medicine, disease modeling, and drug screening applications. Analogous…”
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Investigating the Mechanisms of Neural Stem Cell Mechanotransduction: The Roles of Angiomotin and Hyperglycemia by Kang, Phillip H

“…Neural stem cells (NSCs) are remarkable mediators of structural plasticity in the adult mammalian brain and play important roles in physiological and…”
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FULL-LENGTH INTERLEUKIN-33 PROMOTES INFLAMMATION BUT NOT TH2 RESPONSE IN VIVO IN AN ST2-INDEPENDENT FASHION by Luzina, Irina G., Pickering, Edward M., Kopach, Pavel, Kang, Phillip H., Lockatell, Virginia, Todd, Nevins W., Papadimitriou, John C., McKenzie, Andrew N. J., Atamas, Sergei P.

“…Expression of IL-33 is elevated in patients with pulmonary diseases, and full-length (not proteolytically processed) IL-33 is the predominant form in the lungs…”
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