Search Results - "Kang, Moo Rim"

Active Regulator of SIRT1 Cooperates with SIRT1 and Facilitates Suppression of p53 Activity by Kim, Eun-Joo, Kho, Jeong-Hoon, Kang, Moo-Rim, Um, Soo-Jong

“…Human SIRT1 is an NAD +-dependent deacetylase protein that plays a role in cell death/survival, senescence, and endocrine signaling. While its substrates,…”
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Low Dose Estrogen Supplementation Reduces Mortality of Mice in Estrogen-Dependent Human Tumor Xenograft Model by Kang, Jong Soon, Kang, Moo Rim, Han, Sang-Bae, Yoon, Won Kee, Kim, Jang Hyun, Lee, Taek Chang, Lee, Chang Woo, Lee, Ki Hoon, Lee, Kiho, Park, Song-Kyu, Kim, Hwan Mook

“…Breast cancer is one of the most frequent female cancers in the Western world. Perturbation of estrogen levels by hormone replacement therapy or pregnancy is…”
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Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth by MOO RIM KANG, YANG, Glen, PLACE, Robert F, CHARISSE, Klaus, EPSTEIN-BARASH, Hila, MANOHARAN, Muthiah, LI, Long-Cheng

“…Practical methods for enhancing protein production in vivo remain a challenge. RNA activation (RNAa) is emerging as one potential solution by using…”
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miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells by Kang, Moo Rim, Park, Ki Hwan, Yang, Jeong-Ook, Lee, Chang Woo, Oh, Soo Jin, Yun, Jieun, Lee, Myeong Youl, Han, Sang-Bae, Kang, Jong Soon

“…Recently, microRNAs have been implicated in the regulation of gene expression in terms of both gene silencing and gene activation. Here, we investigated the…”
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LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1α via upregulation of VHL in a colon cancer cell line by Lee, Kyeong, Kang, Jung Eun, Park, Song-Kyu, Jin, Yinglan, Chung, Kyung-Sook, Kim, Hwan-Mook, Lee, Kiho, Kang, Moo Rim, Lee, Myung Kyu, Song, Kyung Bin, Yang, Eun-Gyeong, Lee, Jung-Jun, Won, Misun

“…Hypoxia-inducible factor HIF-1 is responsible for radiation resistance and poor prognosis in cancer therapy. As part of our drug discovery program, a novel HIF…”
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Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment by Kang, Moo Rim, Jo, Sun Ah, Lee, Hyunju, Yoon, Yeo Dae, Kwon, Joo-Hee, Yang, Jeong-Wook, Choi, Byeong Jo, Park, Ki Hwan, Lee, Myeong Youl, Lee, Chang Woo, Lee, Kyeong-Ryoon, Kang, Jong Soon

“…Scytonemin is a yellow-green ultraviolet sunscreen pigment present in different genera of aquatic and terrestrial blue-green algae, including marine…”
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Cardiovascular protective effect of glabridin: Implications in LDL oxidation and inflammation by Kang, Moo Rim, Park, Ki Hwan, Oh, Soo Jin, Yun, Jieun, Lee, Chang Woo, Lee, Myeong Youl, Han, Sang-Bae, Kang, Jong Soon

“…Atherosclerosis is one of the most common causes of death in Western countries and now considered as a chronic inflammatory disease in broad outline. Glaridin,…”
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Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro by Kang, Moo Rim, Lee, Chang Woo, Yun, Jieun, Oh, Soo Jin, Park, Song-Kyu, Lee, Kiho, Kim, Hwan Mook, Han, Sang-Bae, Kim, Hyoung-Chin, Kang, Jong Soon

“…In this study, we investigated the effect of methanolic extract isolated from the root of Lycoris aurea (LA) on the growth of cancer cells and the tube…”
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Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth by Ren, Shancheng, Kang, Moo Rim, Wang, Ji, Huang, Vera, Place, Robert F., Sun, Yinhao, Li, Long-Cheng

“…BACKGROUND RNA activation (RNAa) is a small RNA‐mediated gene regulation mechanism by which expression of a particular gene can be induced by targeting its…”
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Hepatoprotective Effect of Aged Black Garlic Extract in Rodents by Shin, Jung Hyu, Lee, Chang Woo, Oh, Soo Jin, Yun, Jieun, Kang, Moo Rim, Han, Sang-Bae, Park, Heungsik, Jung, Jae Chul, Chung, Yoon Hoo, Kang, Jong Soon

“…In this study, we investigated the hepatoprotective effects of aged black garlic (ABG) in rodent models of liver injury. ABG inhibited carbon…”
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Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells by Kang, Moo-Rim, Lee, Sang-Wang, Um, Elisa, Kang, Hyun Tae, Hwang, Eun Seong, Kim, Eun-Joo, Um, Soo-Jong

“…Human sirtuin 1 (SIRT1) is a NAD⁺-dependent deacetylase that participates in cell death/survival, senescence and metabolism. Although its substrates are well…”
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Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells by MOO RIM KANG, PARK, Song-Kyu, BYUNG WOO KIM, LEE, Kiho, JONG SOON KANG, HWAN MOOK KIM, CHANG WOO LEE, IG JUN CHO, YEONG NANG JO, JEONG WOOK YANG, KIM, Jin-Ah, YUN, Jieun, KI HOON LEE, HYUN JU KWON

“…Widdrol, a natural sesquiterpene present in Juniperus sp., has been shown to exert anticancer and antifungal effects. Emerging evidence has suggested that…”
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Hepatoprotective Effect of Aged Black Garlic Extract in Rodents by Shin, Jung Hyu, Lee, Chang Woo, Oh, Soo Jin, Yun, Jieun, Kang, Moo Rim, Han, Sang-Bae, Park, Heungsik, Jung, Jae Chul, Chung, Yoon Hoo, Kang, Jong Soon

“…In this study, we investigated the hepatoprotective effects of aged black garlic (ABG) in rodent models of liver injury. ABG inhibited carbon…”
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Agelasine D suppresses RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1 and NF-κB by Kang, Moo Rim, Jo, Sun Ah, Yoon, Yeo Dae, Park, Ki Hwan, Oh, Soo Jin, Yun, Jieun, Lee, Chang Woo, Nam, Ki-Hoan, Kim, Youngsoo, Han, Sang-Bae, Yu, Jiyeon, Rho, Jaerang, Kang, Jong Soon

“…In the present study, we investigated the effect of agelasine D (AD) on osteoclastogenesis. Treatment of bone marrow macrophages (BMMs) with receptor activator…”
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Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro by Kang, Moo-Rim, Lee, Chang-Woo, Yun, Ji-Eun, Oh, Soo-Jin, Park, Song-Kyu, Lee, Ki-Ho, Kim, Hwan-Mook, Han, Sang-Bae, Kim, Hyoung-Chin, Kang, Jong-Soon

“…In this study, we investigated the effect of methanolic extract isolated from the root of Lycoris aurea (LA) on the growth of cancer cells and the tube…”
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Differential anti-inflammatory and analgesic effects by enantiomers of zaltoprofen in rodents by Cho, Ig Jun, Lee, Chang Woo, Lee, Myeong Youl, Kang, Moo Rim, Yun, Jieun, Oh, Soo Jin, Han, Sang-Bae, Lee, Kiho, Park, Song-Kyu, Kim, Hwan Mook, Jung, Sang-Hun, Kang, Jong Soon

“…In the present study, we investigated the effect of zaltoprofen enantiomers on inflammation and pain and compared their effect with racemic zaltoprofen…”
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Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells by Kosaka, Mika, Kang, Moo Rim, Yang, Glen, Li, Long-Cheng

“…RNA activation (RNAa) is a mechanism of gene activation triggered by promoter-targeted small double-stranded RNA (dsRNA), also known as small activating RNA…”
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A novel δ-lactam-based histone deacetylase inhibitor, KBH-A42, induces cell cycle arrest and apoptosis in colon cancer cells by Kang, Moo Rim, Kang, Jong Soon, Han, Sang-Bae, Kim, Jang Hyun, Kim, Dong-Myung, Lee, Kiho, Lee, Chang Woo, Lee, Ki Hoon, Lee, Chul Ho, Han, Gyoonhee, Kang, Jong Seong, Kim, Hwan Mook, Park, Song-Kyu

“…In this study, we investigated the anti-tumor activity of KBH-A42 [N-hydroxy-3-(2-oxo-1-(3-phenylpropyl)-1,2,5,6-tetrahydropyridin-3-yl)propanamide], a novel…”
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Lipid-Soluble Ginseng Extract Induces Apoptosis and G0/G1 Cell Cycle Arrest in NCI-H460 Human Lung Cancer Cells by Kang, Moo Rim, Kim, Hwan Mook, Kang, Jong Soon, Lee, Kiho, Lee, Sung Dong, Hyun, Dong-Hoon, In, Man-Jin, Park, Song-Kyu, Kim, Dong Chung

“…This study was performed to elucidate the anticancer mechanism of a lipid-soluble ginseng extract (LSGE) by analyzing induction of apoptosis and arrest of cell…”
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Structure−Activity Relationship Studies of a Series of Novel δ-Lactam-Based Histone Deacetylase Inhibitors by Kim, Hwan Mook, Ryu, Dong-Kyu, Choi, Yongseok, Park, Bum Woo, Lee, Kiho, Han, Sang Bae, Lee, Chang-Woo, Kang, Moo-Rim, Kang, Jong Soon, Boovanahalli, Shanthaveerappa K, Park, Song-Kyu, Han, Jung Whan, Chun, Tae-Gyu, Lee, Hee-Yoon, Nam, Ky-Youb, Choi, Eun Hyun, Han, Gyoonhee

“…We synthesized a series of δ-lactam-based HDAC inhibitors that were identified with various degrees of anti-inflammatory and cell growth inhibitory activities…”
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