Search Results - "Kang, Kidong"

Caspase-1 activates gasdermin A in non-mammals by Billman, Zachary Paul, Kovacs, Stephen Bela, Wei, Bo, Kang, Kidong, Cissé, Ousmane H, Miao, Edward A

“…Gasdermins oligomerize to form pores in the cell membrane, causing regulated lytic cell death called pyroptosis. Mammals encode five gasdermins that can…”
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Post-translational modification of the death receptor complex as a potential therapeutic target in cancer by Kang, Kidong, Lee, So-Ra, Piao, Xuezhe, Hur, Gang Min

“…Programmed cell death is critical to the physiological function of multi-cellular organisms, controlling development, immunity, inflammation, and cancer…”
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Generation of recombinant vaccinia virus and analysis of virus-induced cell death by Liu, Zhijun, Kang, Kidong, Ka-Ming Chan, Francis

“…Vaccinia virus is a large double-stranded DNA virus that is widely used to express foreign genes from different origins. We generated recombinant vaccinia…”
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Brazilin Limits Inflammatory Responses through Induction of Prosurvival Autophagy in Rheumatoid Fibroblast-Like Synoviocytes by Lee, Hyunji, Kang, Seong Wook, Byun, Hee Sun, Jeon, Juhee, Park, Kyeong Ah, Kang, Kidong, Seo, Wonhyoung, Won, Minho, Seok, Jeong Ho, Han, Man-Deuk, Shen, Han-Ming, Hur, Gang Min

“…Brazilin is an active compound of Caesalpinia sappan L. (Leguminosae), which possesses pro-apoptotic and anti-inflammation potentials depending on the specific…”
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Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components by Jeon, Juhee, Lee, Ji Hoon, Park, Kyeong Ah, Byun, Hee Sun, Lee, Hyunji, Lee, Yoonjung, Zhang, Tiejun, Kang, Kidong, Seok, Jeong Ho, Kwon, Hyun-Jung, Han, Man-Deuk, Kang, Seong Wook, Hong, Jang Hee, Hur, Gang Min

“…The ligation of interleukin-1 receptor (IL-1R) or tumor necrosis factor receptor 1 (TNFR1) induces the recruitment of adaptor proteins and their concomitant…”
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Ecdysone Receptor-based Singular Gene Switches for Regulated Transgene Expression in Cells and Adult Rodent Tissues by Lee, Seoghyun, Sohn, Kyung-Cheol, Choi, Dae-Kyoung, Won, Minho, Park, Kyeong Ah, Ju, Sung-Kyu, Kang, Kidong, Bae, Young-Ki, Hur, Gang Min, Ro, Hyunju

“…Controlled gene expression is an indispensable technique in biomedical research. Here, we report a convenient, straightforward, and reliable way to induce…”
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Necroptosis at a glance by Kang, Kidong, Park, Christa, Chan, Francis Ka-Ming

“…Necroptosis, or programmed necrosis, is an inflammatory form of cell death with important functions in host defense against pathogens and tissue homeostasis…”
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Caspase-1 activates gasdermin A in non-mammals by Billman, Zachary Paul, Kovacs, Stephen Bela, Wei, Bo, Kang, Kidong, Cissé, Ousmane H, Miao, Edward A

“…Gasdermins oligomerize to form pores in the cell membrane, causing regulated lytic cell death called pyroptosis. Mammals encode five gasdermins that can…”
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C-27-carboxylated oleanane triterpenoids up-regulate TRAIL DISC assembly via p38 MAPK and CHOP-mediated DR5 expression in human glioblastoma cells by Byun, Hee Sun, Zhou, Wei, Park, InWha, Kang, Kidong, Lee, So-Ra, Piao, Xuezhe, Park, Jin Bong, Kwon, Taeg Kyu, Na, MinKyun, Hur, Gang Min

“…[Display omitted] Despite recent tremendous progress, targeting of TNF-related apoptosis-inducing ligand (TRAIL) as a cancer therapy has limited success in…”
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3‐O‐acetylrubianol C (3AR‐C) induces RIPK1‐dependent programmed cell death by selective inhibition of IKKβ by Kang, Kidong, Quan, Khong Trong, Byun, Hee Sun, Lee, So‐Ra, Piao, Xuezhe, Ju, Eunjin, Park, Kyeong Ah, Sohn, Kyung‐Cheol, Shen, Han‐Ming, Na, MinKyun, Hur, Gang Min

“…In tumor necrosis factor (TNF) signaling, phosphorylation and activation of receptor interacting protein kinase 1 (RIPK1) by upstream kinases is an essential…”
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Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis by Lee, So-Ra, Quan, Khong Trong, Byun, Hee Sun, Park, InWha, Kang, Kidong, Piao, Xuezhe, Ju, Eunjin, Ro, Hyunju, Na, MinKyun, Hur, Gang Min

“…Plant-derived lignans have numerous biological effects including anti-tumor and anti-inflammatory activities. Screening of purified constituents of Rubia…”
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IinQ attenuates systemic inflammatory responses via selectively impairing the Myddosome complex formation upon TLR4 ligation by Kang, Kidong, Won, Minho, Yuk, Jae-Min, Park, Chan-Yong, Byun, Hee Sun, Park, Kyeong Ah, Lee, So-Ra, Kang, Young-Goo, Shen, Han-Ming, Lee, Ill Young, Hur, Gang Min

“…[Display omitted] A specific small-molecule inhibitor of the TLR4 signaling complex upstream of the IKK would likely provide therapeutic benefit for…”
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Terminalia Chebula provides protection against dual modes of necroptotic and apoptotic cell death upon death receptor ligation by Lee, Yoonjung, Byun, Hee Sun, Seok, Jeong Ho, Park, Kyeong Ah, Won, Minho, Seo, Wonhyoung, Lee, So-Ra, Kang, Kidong, Sohn, Kyung-Cheol, Lee, Ill Young, Kim, Hyeong-Geug, Son, Chang Gue, Shen, Han-Ming, Hur, Gang Min

“…Death receptor (DR) ligation elicits two different modes of cell death (necroptosis and apoptosis) depending on the cellular context. By screening a plant…”
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Accelerated degradation of cFLIP L and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis by Lee, So-Ra, Quan, Khong Trong, Byun, Hee Sun, Park, InWha, Kang, Kidong, Piao, Xuezhe, Ju, Eunjin, Ro, Hyunju, Na, MinKyun, Hur, Gang Min

“…Plant-derived lignans have numerous biological effects including anti-tumor and anti-inflammatory activities. Screening of purified constituents of Rubia…”
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