Search Results - "Kang, Ho Bum"

Genetic and metabolic characterization of insomnia by Ban, Hyo-Jeong, Kim, Sang Cheol, Seo, Jungmin, Kang, Ho-Bum, Choi, Jung Kyoon

“…Insomnia is reported to chronically affect 10∼15% of the adult population. However, very little is known about the genetics and metabolism of insomnia. Here we…”
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Genkwadaphnin induces IFN-γ via PKD1/NF-κB/STAT1 dependent pathway in NK-92 cells by Kang, Ho-Bum, Ahn, Kyung-Seop, Oh, Sei-Ryang, Kim, Jae Wha

“…The flower buds of Daphne genkwa Sieb. et Zucc. have been used as a traditional Chinese medicine although their functional mechanisms have not been discovered…”
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PRDM1, a Tumor-Suppressor Gene, is Induced by Genkwadaphnin in Human Colon Cancer SW620 Cells by Kang, Ho-Bum, Lee, Ha-Reum, Jee, Da Jung, Shin, Su-Hyun, Nah, Seong-Su, Yoon, Sun Young, Kim, Jae Wha

“…ABSTRACT Genkwadaphnin (GD‐1) is isolated from the flower buds of Daphne genkwa Siebold et Zuccarini (Thymelaeaceae), and it has been used as a traditional…”
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The secreted protein Amuc_1409 from Akkermansia muciniphila improves gut health through intestinal stem cell regulation by Kang, Eun-Jung, Kim, Jae-Hoon, Kim, Young Eun, Lee, Hana, Jung, Kwang Bo, Chang, Dong-Ho, Lee, Youngjin, Park, Shinhye, Lee, Eun-Young, Lee, Eun-Ji, Kang, Ho Bum, Rhyoo, Moon-Young, Seo, Seungwoo, Park, Sohee, Huh, Yubin, Go, Jun, Choi, Jung Hyeon, Choi, Young-Keun, Lee, In-Bok, Choi, Dong-Hee, Seo, Yun Jeong, Noh, Jung-Ran, Kim, Kyoung-Shim, Hwang, Jung Hwan, Jeong, Ji-Seon, Kwon, Ha-Jeong, Yoo, Hee Min, Son, Mi-Young, Kim, Yeon-Gu, Lee, Dae-Hee, Kim, Tae-Young, Kwon, Hyo-Jung, Kim, Myung Hee, Kim, Byoung-Chan, Kim, Yong-Hoon, Kang, Dukjin, Lee, Chul-Ho

“…Akkermansia muciniphila has received great attention because of its beneficial roles in gut health by regulating gut immunity, promoting intestinal epithelial…”
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Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation by Seo, Jungmin, Kim, Kwoneel, Chang, Dong-Yeop, Kang, Ho-Bum, Shin, Eui-Cheol, Kwon, Jongbum, Choi, Jung Kyoon

“…γH2AX formation by phosphorylation of the histone variant H2AX is the key process in the repair of DNA lesions including those arising at fragile sites under…”
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Genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1/NF-κB signaling pathway by Yoo, Nina, Lee, Ha-Reum, Son, Jang-Mi, Kang, Ho-Bum, Lee, Hee Gu, Yoon, Suk Ran, Yoon, Sun Young, Kim, Jae Wha

“…Graphical abstract…”
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1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression by Yoon, Sun Young, Kang, Ho Bum, Ko, Young-Eun, Shin, Su-Hyun, Kim, Young-Jun, Sohn, Ki-Young, Han, Yong-Hae, Chong, Saeho, Kim, Jae Wha

“…Controlling balance between T-helper type 1 (Th1) and T-helper type 2 (Th2) plays a pivotal role in maintaining the biological rhythm of Th1/Th2 and…”
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Enhancement of Transgene Expression by HDAC Inhibitors in Mouse Embryonic Stem Cells by Kim, Young-Eun, Park, Jeong-A, Park, Sang-Kyu, Kang, Ho-Bum, Kwon, Hyung-Joo, Lee, Younghee

“…Embryonic stem (ES) cells can self-renew and differentiate to various cells depending on the culture condition. Although ES cells are a good model for cell…”
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Tigliane diterpene esters with IFN γ-inducing activity from the leaves of Aleurites fordii by Pei, Yi-Hua, Kim, Jae Wha, Kang, Ho-Bum, Lee, Hyeong-Kyu, Kim, Chan-Soo, Song, Hyuk-Hwan, Chin, Young-Won, Oh, Sei-Ryang

“…Bioactivity-guided fractionation on the leaves of Aleurites fordii led to the isolation of a new tigliane diterpene ester,…”
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Basic fibroblast growth factor activates ERK and induces c-fos in human embryonic stem cell line MizhES1 by Kang, Ho Bum, Kim, Jin Sook, Kwon, Hyung-Joo, Nam, Ki Hoan, Youn, Hyun Soo, Sok, Dai-Eun, Lee, Younghee

“…Human embryonic stem (hES) cells can be maintained in a proliferative undifferentiated state in vitro by growing them on feeder layers of mouse embryonic…”
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Upregulation of NF-κB upon differentiation of mouse embryonic stem cells by Kim, Young-Eun, Kang, Ho-Bum, Park, Jeong-A, Nam, Ki-Hoan, Kwon, Hyung-Joo, Lee, Young-Hee

“…NF-${\kappa}B$ is a transcriptional regulator involved in many biological processes including proliferation, survival, and differentiation. Recently, we…”
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1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression by Yoon, Sun Young, Kang, Ho Bum, Ko, Young-Eun, Shin, Su-Hyun, Kim, Young-Jun, Sohn, Ki-Young, Han, Yong-Hae, Chong, Saeho, Kim, Jae Wha

“…Controlling balance between T-helper type 1 (Th1) and T-helper type 2 (Th2) plays a pivotal role in maintaining the biological rhythm of Th1/Th2 and…”
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NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients by KIM, YOUNG-JUN, KANG, HO-BUM, YIM, HYUN SUN, KIM, JOO HEON, KIM, JAE WHA

“…To discover the molecular mechanism of N-Myc downstream-regulated gene 2 (NDRG2), a newly found differentiation-related tumor suppressor, the relationships…”
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Thymosin beta 4 enhances NK cell cytotoxicity mediated by ICAM-1 by Lee, Ha-reum, Yoon, Sun Young, Kang, Ho-Bum, Park, Sunyoung, Kim, Kyung-Eun, Cho, Young Hoon, Kim, Seonghan, Kim, Chul-woo, Cho, Byung Joo, Lee, Wang Jae, Bang, Sa Ik, Park, Hyunjeong, Cho, Daeho

“…Abstract Thymosin beta 4 (Tβ4), which is the major G-actin sequestering protein, has been shown to have ubiquitous distribution and multiple biological…”
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Upregulation of NF-κB upon differentiation of mouse embryonic stem cells by Kim, Y.E. (Chungbuk National University, Cheongju, Republic of Korea), Kang, H.B. (Chungbuk National University, Cheongju, Republic of Korea), Park, J.A. (Chungbuk National University, Cheongju, Republic of Korea), Nam, K.H. (Bio-Evaluation Center, KRIBB, Cheongwon, Republic of Korea), Kwon, H.J. (Hallym University, Chuncheon, Republic of Korea), Lee, Y.H. (Chungbuk National University, Cheongju, Republic of Korea), E-mail: YHL4177@cbnu.ac.kr

“…NF-κB is a transcriptional regulator involved in many biological processes including proliferation, survival, and differentiation. Recently, we reported that…”
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Enhancement of Transgene Expression by HDAC Inhibitors in Mouse Embryonic Stem Cells by Kim, Young-Eun, Park, Jeong-A, Park, Sang-Kyu, Kang, Ho-Bum, Kwon, Hyung-Joo, Lee, Younghee

“…Embryonic stem (ES) cells can self-renew and differentiate to various cells depending on the culture condition. Although ES cells are a good model for cell…”
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Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e by Joo, Eun-Kyoung, Broxmeyer, Hal E, Kwon, Hyung-Joo, Kang, Ho Bum, Kim, Jin Sook, Lim, Jong Seok, Choe, Yong-Kyoung, Choe, In Seong, Myung, Pyung Keun, Lee, Younghee

“…Stromal cell-derived factor-1 (SDF-1/CXCL12) enhances the survival of hematopoietic stem and progenitor cells in synergy with other cytokines such as…”
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Expression of endothelial cell-specific molecule-1 regulated by hypoxia inducible factor-1α in human colon carcinoma: Impact of ESM-1 on prognosis and its correlation with clinicopathological features by KIM, JOO HEON, PARK, MEE YOUNG, KIM, CHANG NAM, KIM, KYO HYUN, KANG, HO BUM, KIM, KWANG DONG, KIM, JAE WHA

“…Based on a previous finding that endothelial cell-specific molecule-1 (ESM-1) is a potential serum marker for colorectal cancer (CRC), the aim of this study…”
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Genkwadaphnin Induces IFN-[gamma] via PKD1/NF-[kappa]B/STAT1 Dependent Pathway in NK-92 Cells by Kang, Ho-Bum, Ahn, Kyung-Seop, Oh, Sei-Ryang, Kim, Jae Wha

“…The flower buds of Daphne genkwa Sieb. et Zucc. have been used as a traditional Chinese medicine although their functional mechanisms have not been discovered…”
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Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor by Hwang, Jungwon, Kim, Yoonjeong, Kang, Ho Bum, Jaroszewski, Lukasz, Deacon, Ashley M., Lee, Hwiseop, Choi, Won-Chan, Kim, Kyung-Jin, Kim, Cheol-Hee, Kang, Beom Sik, Lee, Jie-Oh, Oh, Tae-Kwang, Kim, Jae Wha, Wilson, Ian A., Kim, Myung Hee

“…Considerable attention has recently been paid to the N-Myc downstream-regulated gene (NDRG) family because of its potential as a tumor suppressor in many human…”
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