Search Results - "Kang, Diane S."
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TENET 2.0: Identification of key transcriptional regulators and enhancers in lung adenocarcinoma
Published in PLoS genetics (14-09-2020)“…Lung cancer is the leading cause of cancer-related death and lung adenocarcinoma is its most common subtype. Although genetic alterations have been identified…”
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Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers
Published in Cancer discovery (01-01-2020)“…Hematogenous metastasis is initiated by a subset of circulating tumor cells (CTC) shed from primary or metastatic tumors into the blood circulation. Thus, CTCs…”
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Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
Published in Advanced science (01-02-2024)“…Keratins are an integral part of cell structure and function. Here, it is shown that ectopic expression of a truncated isoform of keratin 81 (tKRT81) in breast…”
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Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
Published in Cancer discovery (01-09-2020)“…A hallmark of metastasis is the adaptation of tumor cells to new environments. Metabolic constraints imposed by the serine and glycine-limited brain…”
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Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4
Published in Journal of neuroimmunology (15-10-2016)“…Abstract Autoantibodies against SCLC-associated neuronal antigen ELAVL4 (HuD) have been linked to smaller tumors and improved survival, but the antigenic…”
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Abstract 3584: CENPA, MYBL2, and FOXM1 are identified as key transcriptional regulators in lung adenocarcinoma using TENET 2.0
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Lung cancer is the leading cause of cancer-related death in the United States, with lung adenocarcinoma being the most common subtype. Although a…”
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