Search Results - "Kang, Chang‐Yuil"

Roles of NKT cells in cancer immunotherapy by Bae, Eun-Ah, Seo, Hyungseok, Kim, Il-Kyu, Jeon, Insu, Kang, Chang-Yuil

“…Cancer immunotherapy has emerged as an effective therapeutic strategy to treat cancer. Among diverse immune populations, invariant natural killer T (iNKT)…”
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Glucocorticoid-induced tumor necrosis factor receptor–related protein co-stimulation facilitates tumor regression by inducing IL-9–producing helper T cells by Kim, Il-Kyu, Kim, Byung-Seok, Koh, Choong-Hyun, Seok, Jae-Won, Park, Jun-Seok, Shin, Kwang-Soo, Bae, Eun-Ah, Lee, Ga-Eun, Jeon, Hyewon, Cho, Jaebeom, Jung, Yujin, Han, Daehee, Kwon, Byoung S, Lee, Ho-Young, Chung, Yeonseok, Kang, Chang-Yuil

“…GITR signaling inhibits tumor growth by inducing T H 9 cell differentiation, increasing IL-9–dependent dendritic cell function and enhancing cytotoxic T cell…”
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IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours by Seo, Hyungseok, Jeon, Insu, Kim, Byung-Seok, Park, Myunghwan, Bae, Eun-Ah, Song, Boyeong, Koh, Choong-Hyun, Shin, Kwang-Soo, Kim, Il-Kyu, Choi, Kiyoung, Oh, Taegwon, Min, Jiyoun, Min, Byung Soh, Han, Yoon Dae, Kang, Suk-Jo, Shin, Sang Joon, Chung, Yeonseok, Kang, Chang-Yuil

“…During cancer immunoediting, loss of major histocompatibility complex class I (MHC-I) in neoplasm contributes to the evasion of tumours from host immune…”
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Strategy to develop broadly effective multivalent COVID-19 vaccines against emerging variants based on Ad5/35 platform by Chang, Soojeong, Shin, Kwang-Soo, Park, Bongju, Park, Seowoo, Shin, Jieun, Park, Hyemin, Jung, In Kyung, Kim, Jong Heon, Bae, Seong Eun, Kim, Jae-Ouk, Baek, Seung Ho, Kim, Green, Hong, Jung Joo, Seo, Hyungseok, Volz, Erik, Kang, Chang-Yuil

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron strain has evolved into highly divergent variants with several sub-lineages. These…”
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Characterization of age‐associated exhausted CD8+ T cells defined by increased expression of Tim‐3 and PD‐1 by Lee, Kyoo‐A, Shin, Kwang‐Soo, Kim, Ga‐Young, Song, You Chan, Bae, Eun‐Ah, Kim, Il‐Kyu, Koh, Choong‐Hyun, Kang, Chang‐Yuil

“…Summary Aging is accompanied by altered T‐cell responses that result in susceptibility to various diseases. Previous findings on the increased expression of…”
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CX3CR1+ Macrophages and CD8+ T Cells Control Intestinal IgA Production by Kim, Young-In, Song, Joo-Hye, Ko, Hyun-Jeong, Kweon, Mi-Na, Kang, Chang-Yuil, Reinecker, Hans-Christian, Chang, Sun-Young

“…Abstract Secretory IgA is a key host defense mechanism that controls the intestinal microbiota. We investigated the role of CD11c+CX3CR1+CD64+ macrophages in…”
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A critical role for Th17 cell-derived TGF-β1 in regulating the stability and pathogenicity of autoimmune Th17 cells by Choi, Garam, Park, Young-Jun, Cho, Minkyoung, Moon, Heesu, Kim, Daehong, Kang, Chang-Yuil, Chung, Yeonseok, Kim, Byung-Seok

“…Pathogenic conversion of Th17 cells into multifunctional helper T cells or Th1 cells contributes to the pathogenesis of autoimmune diseases; however, the…”
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The restoration of myeloid-derived suppressor cells as functional antigen-presenting cells by NKT cell help and all-trans-retinoic acid treatment by Lee, Jung-Mi, Seo, Jeong-Hwan, Kim, Yeon-Jeong, Kim, Yun-Sun, Ko, Hyun-Jeong, Kang, Chang-Yuil

“…Myeloid‐derived suppressor cells (MDSCs), which accumulate during tumor progression, have been shown to function as important suppressor cells. In a previous…”
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Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2–positive dendritic cells in allergic asthma by Cho, Minkyoung, Lee, Jeong-Eun, Lim, Hoyong, Shin, Hyun-Woo, Khalmuratova, Roza, Choi, Garam, Kim, Hyuk Soon, Choi, Wahn Soo, Park, Young-Jun, Shim, Inbo, Kim, Byung-Seok, Kang, Chang-Yuil, Kim, Jae-Ouk, Tanaka, Shinya, Kubo, Masato, Tung, Hui-Ying, Landers, Cameron T., Corry, David B., Kheradmand, Farrah, Chung, Yeonseok

“…Inhaled protease allergens preferentially trigger TH2-mediated inflammation in allergic asthma. The role of dendritic cells (DCs) on induction of TH2 cell…”
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Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid‐derived suppressor cells by Hong, Eun‐Hye, Chang, Sun‐Young, Lee, Bo‐Ra, Kim, Yun‐Sun, Lee, Jeong‐Mi, Kang, Chang‐Yuil, Kweon, Mi‐Na, Ko, Hyun‐Jeong

“…Myd88 is an important adaptor molecule for the activation of NADPH oxidase and arginase‐1, which are responsible for the suppressive function of…”
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A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model by KO, Hyun-Jeong, KIM, Yeon-Jeong, KIM, Yun-Sun, CHANG, Woo-Sung, KO, Sung-Youl, CHANG, Sun-Young, SAKAGUCHI, Shimon, KANG, Chang-Yuil

“…Her-2/neu is a well-characterized tumor-associated antigen overexpressed in human carcinomas such as breast cancer. Because Her-2/neu is a self-antigen with…”
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Cutting Edge: Programmed Death-1/Programmed Death Ligand 1 Interaction Regulates the Induction and Maintenance of Invariant NKT Cell Anergy by Chang, Woo-Sung, Kim, Ji-Yeon, Kim, Yeon-Jeong, Kim, Yun-Sun, Lee, Jung-Mi, Azuma, Miyuki, Yagita, Hideo, Kang, Chang-Yuil

“…Invariant NKT (iNKT) cells are a distinct subset of T lymphocytes that recognize glycolipid Ags. Upon TCR stimulation, iNKT cells promptly secrete a wide range…”
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Monocyte-Derived Dendritic Cells Dictate the Memory Differentiation of CD8 + T Cells During Acute Infection by Shin, Kwang-Soo, Jeon, Insu, Kim, Byung-Seok, Kim, Il-Kyu, Park, Young-Jun, Koh, Choong-Hyun, Song, Boyeong, Lee, Jeong-Mi, Lim, Jiyoung, Bae, Eun-Ah, Seo, Hyungseok, Ban, Young Ho, Ha, Sang-Jun, Kang, Chang-Yuil

“…Monocyte-derived dendritic cells (moDCs) have been shown to robustly expand during infection; however, their roles in anti-infectious immunity remain unclear…”
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IFN-γ-STAT1 signal regulates the differentiation of inducible Treg: Potential role for ROS-mediated apoptosis by Chang, Jae-Hoon, Kim, Yeon-Jeong, Han, Seung-Hee, Kang, Chang-Yuil

“…Regulatory CD4⁺ T cells are important for the homeostasis of immune cells, and their absence correlates with autoimmune disorders. However, how the immune…”
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IL-17 and IL-21: Their Immunobiology and Therapeutic Potentials by Koh, Choong-Hyun, Kim, Byung-Seok, Kang, Chang-Yuil, Chung, Yeonseok, Seo, Hyungseok

“…Studies over the last 2 decades have identified IL-17 and IL-21 as key cytokines in the modulation of a wide range of immune responses. IL-17 serves as a…”
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Efficacy and safety of BVAC-C in HPV type 16- or 18-positive cervical carcinoma who failed 1st platinum-based chemotherapy: a phase I/IIa study by Choi, Chel Hun, Lee, Jeong-Won, Bae, Duk-Soo, Kang, Eun-Suk, Cho, Duck, Kim, Yong-Man, Kim, Kidong, Kim, Jae-Weon, Kim, Hee Seung, Kim, Young-Tae, Lee, Jung-Yun, Lim, Myong Cheol, Oh, Taegwon, Song, Boyeong, Jeon, Insu, Park, Myunghwan, Kim, Wu Hyun, Kang, Chang-Yuil, Kim, Byoung-Gie

“…BVAC-C, a B cell- and monocyte-based immunotherapeutic vaccine transfected with recombinant HPV E6/E7, was well tolerated in HPV-positive recurrent cervical…”
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The Wnt inhibitor secreted Frizzled‐Related Protein 1 (sFRP1) promotes human Th17 differentiation by Lee, Yoon‐Sook, Lee, Kyoo‐A, Yoon, Hae‐Bom, Yoo, Seung‐Ah, Park, Young Woo, Chung, Yeonseok, Kim, Wan‐Uk, Kang, Chang‐Yuil

“…Wnt/β‐catenin signaling plays a crucial role during embryogenesis and tumorigenesis, and in T cells, promotes the differentiation of Th2 cells. However, the…”
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Serum amyloid A3 exacerbates cancer by enhancing the suppressive capacity of myeloid‐derived suppressor cells via TLR2‐dependent STAT3 activation by Lee, Jung‐Mi, Kim, Eun‐Kyung, Seo, Hyungseok, Jeon, Insu, Chae, Min‐Ji, Park, Young‐Jun, Song, Boyeong, Kim, Yun‐Sun, Kim, Yeon‐Jeong, Ko, Hyun‐Jeong, Kang, Chang‐Yuil

“…Myeloid‐derived suppressor cells (MDSCs), which suppress diverse innate and adaptive immune responses and thereby provide an evasion mechanism for tumors, are…”
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Conversion of Th2 memory cells into Foxp3⁺ regulatory T cells suppressing Th2-mediated allergic asthma by Kim, Byung-Seok, Kim, Il-Kyu, Park, Young-Jun, Kim, Yun-Sun, Kim, Yeon-Jeong, Chang, Woo-Sung, Lee, Yoon-Sook, Kweon, Mi-Na, Chung, Yeonseok, Kang, Chang-Yuil

“…Genetic and epigenetic programming of T helper (Th) cell subsets during their polarization from naive Th cells establishes long-lived memory Th cells that…”
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Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer by Kim, Byung-Seok, Kuen, Da-Sol, Koh, Choong-Hyun, Kim, Hyung-Don, Chang, Seon Hee, Kim, Sehui, Jeon, Yoon Kyung, Park, Young-Jun, Choi, Garam, Kim, Jiyeon, Kang, Keon Wook, Kim, Hye Young, Kang, Suk-Jo, Hwang, Shin, Shin, Eui-Cheol, Kang, Chang-Yuil, Dong, Chen, Chung, Yeonseok

“…BackgroundMultiple types of immune cells producing IL-17 are found in the tumor microenvironment. However, their roles in tumor progression and exhaustion of…”
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