Search Results - "Kanerva, J."

Forest sector circular economy development in Finland: A regional study on sustainability driven competitive advantage and an assessment of the potential for cascading recovered solid wood by Husgafvel, R., Linkosalmi, L., Hughes, M., Kanerva, J., Dahl, O.

“…The circular economy is among the key contemporary policy goals both in Europe and in Finland. Therefore, sustainability and life cycle thinking are…”
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High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia by SKARBY, T. V. Ch, ANDERSON, H, HELDRUP, J, KANERVA, J. A, SEIDEL, H, SCHMIEGELOW, K

“…We explored the relationship between time to relapse and different exposure variables (serum methotrexate (S-MTX) 23, 36 and 42 h after start of…”
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Benthic conditions around a historic shipwreck: Vrouw Maria (1771) in the northern Baltic proper by Ruuskanen, A.T., Kraufvelin, P., Alvik, R., Díaz, E.R., Honkonen, J., Kanerva, J., Karell, K., Kekäläinen, P., Lappalainen, J., Mikkola, R., Mustasaari, T., Nappu, N., Nieminen, A., Roininen, J., Svahnbäck, K.

“…Since her shipwreck in 1771, the wooden vessel Vrouw Maria has been lying on the seabed at 41m depth on the border between the Archipelago Sea and the northern…”
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Oral Doxycycline Compared to Intravenous Ceftriaxone in the Treatment of Lyme Neuroborreliosis: A Multicenter, Equivalence, Randomized, Open-label Trial by Kortela, Elisa, Kanerva, Mari J, Puustinen, Juha, Hurme, Saija, Airas, Laura, Lauhio, Anneli, Hohenthal, Ulla, Jalava-Karvinen, Päivi, Nieminen, Tuomas, Finnilä, Taru, Häggblom, Tony, Pietikäinen, Annukka, Koivisto, Mari, Vilhonen, Johanna, Marttila-Vaara, Minna, Hytönen, Jukka, Oksi, Jarmo

“…Lyme neuroborreliosis (LNB) is often treated with intravenous ceftriaxone even if doxycycline is suggested to be noninferior to ceftriaxone. We evaluated the…”
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C6 peptide enzyme immunoassay in Lyme borreliosis serology by Rouhiainen, Meri, Pietikäinen, Annukka, Kortela, Elisa, Kanerva, Mari J., Oksi, Jarmo, Hytönen, Jukka

“…The cut-off values used in C6 peptide-based enzyme immunoassay (EIA), a widely used test in Lyme borreliosis (LB) serology, have not been thoroughly analysed…”
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Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids by Lönnerholm, G, Nordgren, A, Frost, B-M, Jonsson, O G, Kanerva, J, Nygaard, R, Schmiegelow, K, Larsson, R, Forestier, E

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Consumption of healthcare services and antibiotics in patients with presumed disseminated Lyme borreliosis before and after evaluation of an infectious disease specialist by Kortela, Elisa, Kanerva, Mari J, Kurkela, Satu, Oksi, Jarmo, Koivisto, Mari, Järvinen, Asko

“…Our objective was to study the consumption of healthcare services and antibiotics in patients with suspicion of disseminated Lyme borreliosis (LB) before and…”
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Cellular drug sensitivity in MLL‐rearranged childhood acute leukaemia is correlated to partner genes and cell lineage by Palle, J., Frost, B. M., Forestier, E., Gustafsson, G., Nygren, P., Hellebostad, M., Jonsson, O. G., Kanerva, J., Schmiegelow, K., Larsson, R., Lönnerholm, G.

“…Summary Rearrangements in the 11q23 region, the site of the mixed lineage leukaemia (MLL) gene, are found in both childhood acute myeloid (AML) and…”
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Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemia by Frost, B M, Forestier, E, Gustafsson, G, Nygren, P, Hellebostad, M, Jonmundsson, G, Kanerva, J, Schmiegelow, K, Larsson, R, Lönnerholm, G

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The Role of Small Nucleolar RNAs As Putative Biomarkers of Chemoresistance in Pediatric Acute Lymphoblastic Leukemia by Krali, Olga, Enblad, Anna Pia, Blom, Kristin, Andersson, Claes, Frost, Britt-Marie, Palle, Josefine, Harila, Arja, Lohi, Olli, Forestier, Erik, Kanerva, Jukka, Flægstad, Trond, Jónsson, Ólafur G, Schmiegelow, Kjeld, Heyman, Mats, Nygren, Peter, Larsson, Rolf, Lönnerholm, Gudmar, Nordlund, Jessica

“…Background Many previous studies have focused on the molecular landscape of pediatric acute lymphoblastic leukemia (ALL) with the aim to identify genetic…”
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Mapping Chemo-Resistance Profiles of Pediatric Acute Leukemia through Integration of Ex-Vivo Drug Screens with Molecular Data by Enblad, Anna Pia, Krali, Olga, Blom, Kristin, Andersson, Claes, Frost, Britt-Marie, Palle, Josefine, Harila, Arja, Forestier, Erik, Kanerva, Jukka, Flægstad, Trond, Jónsson, Ólafur G, Schmiegelow, Kjeld, Heyman, Mats, Nygren, Peter, Larsson, Rolf, Lönnerholm, Gudmar, Nordlund, Jessica

“…Introduction While novel approaches for treatment of acute lymphoblastic leukemia (ALL) in children have resulted in significant improvements in survival…”
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Asparaginase‐associated pancreatitis in children with acute lymphoblastic leukaemia in the NOPHO ALL2008 protocol by Raja, Raheel A., Schmiegelow, Kjeld, Albertsen, Birgitte K., Prunsild, Kaie, Zeller, Bernward, Vaitkeviciene, Goda, Abrahamsson, Jonas, Heyman, Mats, Taskinen, Mervi, Harila‐Saari, Arja, Kanerva, Jukka, Frandsen, Thomas L.

“…Summary L‐asparaginase is an important drug in the treatment of childhood acute lymphoblastic leukaemia (ALL). Treatment is associated with several toxicities,…”
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Delayed elimination of high‐dose methotrexate and use of carboxypeptidase G2 in pediatric patients during treatment for acute lymphoblastic leukemia by Svahn, Thommy, Mellgren, Karin, Harila‐Saari, Arja, Åsberg, Ann, Kanerva, Jukka, Jónsson, Ólafur, Vaitkeviciene, Goda, Stamm Mikkelssen, Torben, Schmiegelow, Kjeld, Heldrup, Jesper

“…Background Carboxypeptidase G2 (CPDG2) can be used as rescue treatment in cases of delayed methotrexate elimination (DME) and Mtx‐induced nephrotoxicity…”
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Early suppression policies protected pregnant women from COVID‐19 in 2020: A population‐based surveillance from the Nordic countries by Varpula, Reetta, Äyräs, Outi, Aabakke, Anna J. M., Klungsøyr, Kari, Svanvik, Teresia, Kanerva, Julia, Jonasdottir, Eva, Mentzoni, Camilla Tjønneland, Thurn, Lars, Jones, Elin, Fredriksson, Lisa, Pettersson, Karin, Nyfløt, Lill Trine, Vangen, Siri, Røe, Kjerstine, Júlíusson, Pétur B., Källén, Karin, Gissler, Mika, Pyykönen, Aura, Jakobsson, Maija, Krebs, Lone, Engjom, Hilde Marie

“…Introduction The Coronavirus 2019 Disease (COVID‐19) pandemic reached the Nordic countries in March 2020. Public health interventions to limit viral…”
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DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia by Milani, Lili, Lundmark, Anders, Kiialainen, Anna, Nordlund, Jessica, Flaegstad, Trond, Forestier, Erik, Heyman, Mats, Jonmundsson, Gudmundur, Kanerva, Jukka, Schmiegelow, Kjeld, Söderhäll, Stefan, Gustafsson, Mats G., Lönnerholm, Gudmar, Syvänen, Ann-Christine

“…Despite improvements in the prognosis of childhood acute lymphoblastic leukemia (ALL), subgroups of patients would benefit from alternative treatment…”
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Effects of germ line DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia by Tulstrup, M., Moriyama, T., Jiang, C., Grosjean, M., Nersting, J., Abrahamsson, Jonas, Grell, K., Hjalgrim, L. L., Jonsson, O. G., Kanerva, J., Lund, B., Nielsen, S. N., Nielsen, R. L., Quist-Paulsen, P., Pruunsild, K., Wolthers, B. O., Zhang, H., Gupta, R., Yang, J. J., Schmiegelow, K.

“…Methotrexate (MTX) during maintenance therapy is essential for curing acute lymphoblastic leukemia (ALL), but dosing strategies aiming at adequate treatment…”
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No association between relapse hazard and thiopurine methyltransferase geno- or phenotypes in non-high risk acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study by Nielsen, Stine Nygaard, Toksvang, Linea Natalie, Grell, Kathrine, Nersting, Jacob, Abrahamsson, Jonas, Lund, Bendik, Kanerva, Jukka, Jónsson, Ólafur Gísli, Vaitkeviciene, Goda, Pruunsild, Kaie, Appell, Malin Lindqvist, Hjalgrim, Lisa Lyngsie, Schmiegelow, Kjeld

“…Purpose 6-mercaptopurine(6MP)/methotrexate maintenance therapy is essential to reduce relapse of childhood acute lymphoblastic leukemia (ALL). Common germline…”
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STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells by Murumägi, Astrid, Ungureanu, Daniela, Arjama, Mariliina, Bützow, Ralf, Lohi, Jouko, Sariola, Hannu, Kanerva, Jukka, Koskenvuo, Minna, Kallioniemi, Olli

“…•First study to establish in real-time STRN-ALK fusion positive pediatric patient-derived cancer cells (PDCs).•Ex vivo sensitivity testing of PDCs to 527…”
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Risk factors for treatment related mortality in childhood acute lymphoblastic leukaemia by Lund, Bendik, Åsberg, Ann, Heyman, Mats, Kanerva, Jukka, Harila-Saari, Arja, Hasle, Henrik, Söderhäll, Stefan, Jónsson, Ólafur Gisli, Lydersen, Stian, Schmiegelow, Kjeld

“…Background In spite of major improvements in the cure rate of childhood acute lymphoblastic leukaemia (ALL), 2–4% of patients still die from treatment related…”
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Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study by El-Serafi, Ahmed, He, Rui, Zheng, Wenyi, Benkossou, Fadwa, Oerther, Sandra, Zhao, Ying, Mellgren, Karin, Gustafsson, Britt, Heilmann, Carsten, Kanerva, Jukka, Lotfi, Kourosh, Toporski, Jacek, Sundin, Mikael, Höglund, Martin, Mattsson, Jonas, El-Serafi, Ibrahim, Hassan, Moustapha

“…Vitamin D (Vit-D), an essential nutrient, interacts with different drugs including chemotherapeutic agents like busulphan, an alkylating agent used for…”
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