Search Results - "Kaneko, Tatsuroh"

Organ protection by SGLT2 inhibitors: role of metabolic energy and water conservation by Marton, Adriana, Kaneko, Tatsuroh, Kovalik, Jean-Paul, Yasui, Atsutaka, Nishiyama, Akira, Kitada, Kento, Titze, Jens

“…Therapeutic inhibition of the sodium–glucose co-transporter 2 (SGLT2) leads to substantial loss of energy (in the form of glucose) and additional solutes (in…”
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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition by Tomita, Issei, Kume, Shinji, Sugahara, Sho, Osawa, Norihisa, Yamahara, Kosuke, Yasuda-Yamahara, Mako, Takeda, Naoko, Chin-Kanasaki, Masami, Kaneko, Tatsuroh, Mayoux, Eric, Mark, Michael, Yanagita, Motoko, Ogita, Hisakazu, Araki, Shin-ichi, Maegawa, Hiroshi

“…SGLT2 inhibitors offer strong renoprotection in subjects with diabetic kidney disease (DKD). But the mechanism for such protection is not clear. Here, we…”
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Hypothalamic orexinergic neurons modulate pain and itch in an opposite way: pain relief and itch exacerbation by Kaneko, Tatsuroh, Kuwaki, Tomoyuki, Kashiwadani, Hideki

“…Pain and itch are recognized as antagonistic sensations; pain suppresses itch and inhibition of pain generates itch. There is still a lack of evidence about…”
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In Vitro Differentiation of Chicken Astrocytes: Growth, Morphology, and Protein Expression of Astrocytes in Primary Cultures by Tsukuda, Satoko, Tamura, Akiko, Matsumoto, Kei, Fujita, Yuki, Nakata, Shihoko, Kaneko, Tatsuroh, Nakayama, Ayako, Nakagawa, Hiroyuki, Terasaki, Asako G

“…Astrocytes regulate synaptic transmission in the central nervous system. Astrocytes in vivo have "stems" that express glial fibrillary acidic protein (GFAP),…”
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Orexin neurons play contrasting roles in itch and pain neural processing via projecting to the periaqueductal gray by Kaneko, Tatsuroh, Oura, Asuka, Imai, Yoshiki, Kusumoto-Yoshida, Ikue, Kanekura, Takuro, Okuno, Hiroyuki, Kuwaki, Tomoyuki, Kashiwadani, Hideki

“…Pain and itch are recognized as antagonistically regulated sensations; pain suppresses itch, whilst pain inhibition enhances itch. The neural mechanisms at the…”
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The opposite roles of orexin neurons in pain and itch neural processing by Kaneko, Tatsuroh, Kuwaki, Tomoyuki

“…Pain and itch are antagonistically regulated sensations; pain suppresses itch, and inhibition of pain enhances itch. Understanding the central neural circuit…”
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Efficacy and safety of empagliflozin as add‐on to insulin in Japanese patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled trial by Sone, Hirohito, Kaneko, Tatsuroh, Shiki, Kosuke, Tachibana, Yoshifumi, Pfarr, Egon, Lee, Jisoo, Tajima, Naoko

“…Aim To assess the efficacy and safety of empagliflozin as add‐on to insulin in Japanese patients with type 2 diabetes (T2D). Materials and methods This…”
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Empagliflozin Induces Transient Diuresis Without Changing Long-Term Overall Fluid Balance in Japanese Patients With Type 2 Diabetes by Yasui, Atsutaka, Lee, Ganghyuck, Hirase, Tetsuaki, Kaneko, Tatsuroh, Kaspers, Stefan, von Eynatten, Maximilian, Okamura, Tomoo

“…Introduction Empagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, ameliorates hyperglycemia in patients with type 2 diabetes (T2D) by inducing…”
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FO053ROLE OF KETONE BODY METABOLISM IN SGLT2 INHIBITOR-MEDIATED RENOPROTECTION IN HIGH FAT DIET-FED APOE-KNOCKOUT MICE by Tomita, Issei, Kume, Shinji, Yamahara, Kosuke, Yasuda-Yamahara, Mako, Takeda, Naoko, Osawa, Norihisa, Chin-Kanasaki, Masami, Kaneko, Tatsuroh, Pieper, Michael, Araki, Shin-Ichi, Maegawa, Hiroshi

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SP430Potential role for ketone body metabolism in an SGLT2 inhibitor-mediated anti-albuminuric effect in type 2 diabetic db/db mice by Kume, Shinji, Tomita, Issei, Yamahara, Kosuke, Yasuda-Yamahara, Mako, Takeda, Naoko, Osawa, Norihisa, Chin-Kanasaki, Masami, Kaneko, Tatsuroh, Pieper, Michael, Araki, Shin-Ichi, Maegawa, Hiroshi

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