Search Results - "Kane, M. P."
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Clinical prevalence of Lewy body dementia
Published in Alzheimer's research & therapy (15-02-2018)“…The prevalence of dementia with Lewy bodies (DLB) and dementia in Parkinson's disease (PDD) in routine clinical practice is unclear. Prevalence rates observed…”
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Phase I study of weekly paclitaxel in combination with pazopanib and lapatinib in advanced solid malignancies
Published in British journal of cancer (27-05-2014)“…Background: We assessed the maximum tolerated regimen (MTR) and dose-limiting toxicities of pazopanib and lapatinib in combination with weekly paclitaxel, and…”
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The effects of partial carpal fusions on wrist range of motion
Published in The Journal of hand surgery, European volume (01-06-2016)“…The objective of this investigation was to evaluate the effects of different partial wrist fusions on wrist motion. A total of 20 cadaveric wrists were tested…”
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Plasma metabolites distinguish dementia with Lewy bodies from Alzheimer's disease: a cross-sectional metabolomic analysis
Published in Frontiers in aging neuroscience (04-01-2024)“…In multifactorial diseases, alterations in the concentration of metabolites can identify novel pathological mechanisms at the intersection between genetic and…”
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Developing a person-centered stated preference survey for dementia with Lewy bodies: value of a personal and public involvement process
Published in Frontiers in dementia (15-07-2024)“…The development of high-quality stated preference (SP) surveys requires a rigorous design process involving engagement with representatives from the target…”
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Clinical diagnosis of Lewy body dementia
Published in BJPsych open (01-07-2020)“…Lewy body dementia, consisting of both dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), is considerably under-recognised clinically…”
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Dementia with Lewy bodies: Impact of co‐pathologies and implications for clinical trial design
Published in Alzheimer's & dementia (01-01-2023)“…Dementia with Lewy bodies (DLB) is clinically defined by the presence of visual hallucinations, fluctuations, rapid eye movement (REM) sleep behavioral…”
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Implementation of personalised medicine policies in mental healthcare: results from a stated preference study in the UK
Published in BJPsych open (01-03-2022)“…Public support for the implementation of personalised medicine policies (PMPs) within routine care is important owing to the high financial costs involved and…”
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Uniformity of cardiac 123I-MIBG uptake on SPECT images in older adults with normal cognition and patients with dementia
Published in Journal of nuclear cardiology (01-10-2021)“…Some studies report that assessing regional 123I-cardiac MIBG uptake can aid in the diagnosis of Lewy body disease, but others report heterogeneity in healthy…”
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Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer’s Disease: A Pragmatic Review for Clinicians
Published in Neurology and therapy (01-06-2024)“…This pragmatic review synthesises the current understanding of prodromal dementia with Lewy bodies (pDLB) and prodromal Alzheimer’s disease (pAD), including…”
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How Do Psychiatrists Apply the Minimum Clinically Important Difference to Assess Patient Responses to Treatment?
Published in MDM policy & practice (01-07-2016)“…Symptom report scales are used in clinical practice to monitor patient outcomes. Using them permits the definition of a minimum clinically important difference…”
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Advance care plan barriers in older patients with end-stage renal disease: a qualitative nephrologist interview study
Published in BMJ supportive & palliative care (01-12-2020)“…Older patients with end-stage renal disease are willing participants in advance care planning but just over 10% are engaged in this process. Nephrologists fear…”
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Cardiac 123I-MIBG normal uptake values are population-specific: Results from a cohort of controls over 60 years of age
Published in Journal of nuclear cardiology (01-08-2021)“…Cardiac 123I-MIBG image interpretation is affected by population differences and technical factors. We recruited older adults without cognitive decline and…”
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14
Introduction of a Management Toolkit for Lewy Body Dementia: A Pilot Cluster‐Randomized Trial
Published in Movement disorders (01-01-2021)“…ABSTRACT Background Lewy body dementia, comprising both dementia with Lewy bodies and Parkinson's disease dementia, is challenging to manage because of a…”
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15
Arabitol dehydrogenase as a selectable marker for rice
Published in Plant cell reports (01-12-2005)“…Arabitol dehydrogenase has been adapted for use as a plant selectable marker. Arabitol is a five-carbon sugar alcohol that can be used by E. coli strain C, but…”
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Mid-term outcomes of routine proximal row carpectomy compared with proximal row carpectomy with dorsal capsular interposition arthroplasty for the treatment of late-stage arthropathy of the wrist
Published in The bone & joint journal (01-02-2018)“…The aims of this study were to compare the mid-term outcomes of patients with late-stage arthritis of the wrist treated with proximal row carpectomy (PRC) and…”
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The gap between policy and practice: a systematic review of patient-centred care interventions in chronic heart failure
Published in Heart failure reviews (01-11-2015)“…Patient-centred care (PCC) is recommended in policy documents for chronic heart failure (CHF) service provision, yet it lacks an agreed definition. A…”
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Biochemical characterization of the yeast vacuolar H+-ATPase
Published in The Journal of biological chemistry (15-11-1989)“…The yeast vacuolar proton-translocating ATPase was isolated by two different methods. A previously reported purification of the enzyme (Uchida, E., Ohsumi, Y.,…”
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Assembly and targeting of peripheral and integral membrane subunits of the yeast vacuolar H(+)-ATPase
Published in The Journal of biological chemistry (05-01-1992)“…Previous purification and characterization of the yeast vacuolar proton-translocating ATPase (H(+)-ATPase) have indicated that it is a multisubunit complex…”
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Partial assembly of the yeast vacuolar H+-ATPase in mutants lacking one subunit of the enzyme
Published in The Journal of biological chemistry (05-08-1993)“…Partial assembly of the peripheral and integral membrane sectors of the yeast vacuolar H(+)-ATPase has been detected in mutants lacking one subunit of the…”
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