Search Results - "Kane, Cynthia J.M"

Platelet-rich plasma gel promotes differentiation and regeneration during equine wound healing by Carter, Charleata A, Jolly, David G, Worden, Charles E, Hendren, Dennis G, Kane, Cynthia J.M

“…Nonhealing wounds of the lower equine limb represent a challenging model. The platelet is a natural source of a myriad of growth factors and cytokines that…”
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Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone by Cippitelli, Andrea, Domi, Esi, Ubaldi, Massimo, Douglas, James C, Li, Hong Wu, Demopulos, Gregory, Gaitanaris, George, Roberto, Marisa, Drew, Paul D, Kane, Cynthia J.M, Ciccocioppo, Roberto

“…Highlights • The PPARγ agonist pioglitazone reduces alcohol-induced neurodegeneration. • Pioglitazone prevents alcohol-induced expression of pro-inflammatory…”
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Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists by Kane, Cynthia J.M, Phelan, Kevin D, Han, Lihong, Smith, Renea R, Xie, Jin, Douglas, James C, Drew, Paul D

“…Highlight ► We demonstrate that PPAR-γ agonists protect neurons and microglia from ethanol induced neuropathology in primary cultures and in a novel in vivo…”
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Proceedings of the 2009 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group by Zhou, Feng C, Kane, Cynthia J.M, Smith, Susan M

“…Abstract The annual meeting of the Fetal Alcohol Spectrum Disorders Study Group (FASDSG) was held on June 20, 2009 in San Diego, CA, as a satellite of the…”
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Proceedings of the 2010 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group by Kane, Cynthia J.M, Smith, Susan M, Miranda, Rajesh C, Kable, Julie

“…Abstract The annual meeting of the Fetal Alcohol Spectrum Disorders Study Group (FASDSG) was held on June 26, 2010 in San Antonio, TX, as a satellite of the…”
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Ethanol exposure of neonatal rats does not increase biomarkers of oxidative stress in isolated cerebellar granule neurons by Kane, Cynthia J.M, Chang, Jason Y, Roberson, Paula K, Garg, Tarun K, Han, Lihong

“…Abstract Oxidative stress is a candidate mechanism for ethanol neuropathology in fetal alcohol spectrum disorders. Oxidative stress often involves production…”
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Proceedings of the 2008 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group by Thomas, Jennifer D, Zhou, Feng C, Kane, Cynthia J.M

“…Abstract The annual meeting of the Fetal Alcohol Spectrum Disorders Study Group (FASDSG) was held on June 28, 2008 in Washington DC, as a satellite to the…”
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Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum by Light, Kim E, Brown, Donna P, Newton, Bruce W, Belcher, Scott M, Kane, Cynthia J.M

“…Ethanol causes loss of Purkinje cells in the cerebellum during the early stages of differentiation and maturation by a presently unknown mechanism. Neuronal…”
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Neuroinflammatory contribution of microglia and astrocytes in fetal alcohol spectrum disorders by Kane, Cynthia J. M., Drew, Paul D.

“…Ethanol exposure to the fetus during pregnancy can result in fetal alcohol spectrum disorders (FASD). These disorders vary in severity, can affect multiple…”
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Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation by Langberg, C W, Hauer-Jensen, M, Sung, C C, Kane, C J

“…The molecular and cellular mechanisms that regulate the radiation-induced fibrotic response in the intestine are not known. In addition to increased amounts of…”
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Inflammatory responses to alcohol in the CNS: nuclear receptors as potential therapeutics for alcohol‐induced neuropathologies by Kane, Cynthia J. M., Drew, Paul D.

“…Review on alcohol induction of neuroinflammation and the potential for nuclear receptor agonist in prevention or treatment of FASD and AUD. Fetal alcohol…”
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Pioglitazone Blocks Ethanol Induction of Microglial Activation and Immune Responses in the Hippocampus, Cerebellum, and Cerebral Cortex in a Mouse Model of Fetal Alcohol Spectrum Disorders by Drew, Paul D., Johnson, Jennifer W., Douglas, James C., Phelan, Kevin D., Kane, Cynthia J. M.

“…Background Fetal alcohol spectrum disorders (FASD) result from fetal exposure to alcohol and are the leading cause of mental retardation in the United States…”
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Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period by Pinson, Marisa R., Holloway, Kalee N., Douglas, James C., Kane, Cynthia J. M., Miranda, Rajesh C., Drew, Paul D.

“…Background The developing hippocampus and cerebellum, unique among brain regions, exhibit a secondary surge in neurogenesis during the third trimester of…”
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Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders by Kane, Cynthia J. M., Douglas, James C., Rafferty, Tonya, Johnson, Jennifer W., Niedzwiedz‐Massey, Victoria M., Phelan, Kevin D., Majewska, Ania Katarzyna, Drew, Paul D.

“…Fetal alcohol spectrum disorders (FASD) are alarmingly common, result in significant personal and societal loss, and there is no effective treatment for these…”
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Fetal alcohol spectrum disorders and neuroimmune changes by Drew, Paul D, Kane, Cynthia J M

“…The behavioral consequences of fetal alcohol spectrum disorders (FASD) are serious and persist throughout life. The causative mechanisms underlying FASD are…”
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Effects of Ethanol on Immune Response in the Brain: Region-Specific Changes in Adolescent Versus Adult Mice by Kane, Cynthia J. M., Phelan, Kevin D., Douglas, James C., Wagoner, Gail, Johnson, Jennifer W., Xu, Jihong, Phelan, Patrick S., Drew, Paul D.

“…Background Alcohol use occurs across the life span beginning in adolescence and continuing through adulthood. Ethanol (EtOH)‐induced pathology varies with age…”
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Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders by Niedzwiedz-Massey, Victoria M., Douglas, James C., Rafferty, Tonya, Wight, Patricia A., Kane, Cynthia J.M., Drew, Paul D.

“…Fetal alcohol spectrum disorders (FASD) are alarmingly common and result in significant personal and societal loss. Neuropathology of the hippocampus is common…”
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Prenatal Ethanol Exposure and Postnatal Environmental Intervention Alter Dopaminergic Neuron and Microglia Morphology in the Ventral Tegmental Area During Adulthood by Aghaie, Claudia I., Hausknecht, Kathryn A., Wang, Ruixiang, Dezfuli, Parisa Halaji, Haj‐Dahmane, Samir, Kane, Cynthia J. M., Sigurdson, Wade J., Shen, Roh‐Yu

“…Background Prenatal ethanol exposure (PE) impairs midbrain dopaminergic (DA) neuron function, which might contribute to various cognitive and behavioral…”
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Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation by Niedzwiedz-Massey, Victoria M., Douglas, James C., Rafferty, Tonya, Johnson, Jennifer W., Holloway, Kalee N., Berquist, Michael D., Kane, Cynthia J.M., Drew, Paul D.

“…Background: Hippocampal and cerebellar neuropathology occurs in individuals with alcohol use disorders (AUD), resulting in impaired cognitive and motor…”
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Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders by Niedzwiedz-Massey, Victoria M., Douglas, James C., Rafferty, Tonya, Kane, Cynthia J.M., Drew, Paul D.

“…Fetal alcohol spectrum disorders (FASD) are alarmingly common, result in significant personal and societal loss, and there are no effective treatments for…”
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