Search Results - "Kane, A. S."

Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion by Eftekhari, S, Salvatore, C.A, Calamari, A, Kane, S.A, Tajti, J, Edvinsson, L

“…Abstract Calcitonin gene related peptide (CGRP) has a key role in migraine and recently CGRP receptor antagonists have demonstrated clinical efficacy in the…”
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Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries by Chan, K Y, Edvinsson, L, Eftekhari, S, Kimblad, P O, Kane, S A, Lynch, J, Hargreaves, R J, de Vries, R, Garrelds, I M, van den Bogaerdt, A J, Danser, A H J, Maassenvandenbrink, A

“…The sensory neuropeptide calcitonin gene-related peptide (CGRP) plays a role in primary headaches, and CGRP receptor antagonists are effective in migraine…”
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CGRP receptor antagonists: toward a novel migraine therapy by Salvatore, C A, Kane, S A

“…Migraine remains one of the most prevalent and disabling neurological disorders that often affects a person during their most productive years. Migraine…”
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Reproducibility of the capsaicin‐induced dermal blood flow response as assessed by laser Doppler perfusion imaging by Van der Schueren, B. J., De Hoon, J. N., Vanmolkot, F. H., Van Hecken, A., Depre, M., Kane, S. A., De Lepeleire, I., Sinclair, S. R.

“…What is already known about this subject • Capsaicin rapidly produces local neurogenic inflammation (characterized by oedema and erythema) when locally…”
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Mapping the CGRP receptor ligand binding domain: Tryptophan-84 of RAMP1 is critical for agonist and antagonist binding by Moore, E.L., Gingell, J.J., Kane, S.A., Hay, D.L., Salvatore, C.A.

“…The calcitonin receptor-like receptor (CLR) associates with the accessory protein RAMP1 to form a receptor for the neuropeptide calcitonin gene-related peptide…”
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Calcitonin gene-related peptide8-37 antagonizes capsaicin-induced vasodilation in the skin: evaluation of a human in vivo pharmacodynamic model by Van der Schueren, B J, Rogiers, A, Vanmolkot, F H, Van Hecken, A, Depré, M, Kane, S A, De Lepeleire, I, Sinclair, S R, de Hoon, J N

“…The purpose of this study was to identify the mediators involved in capsaicin-induced vasodilation in the human skin and to evaluate a pharmacodynamic model…”
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Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat by Oliver, K. R., Kane, S. A., Salvatore, C. A., Mallee, J. J., Kinsey, A. M., Koblan, K. S., Keyvan-Fouladi, N., Heavens, R. P., Wainwright, A., Jacobson, M., Dickerson, I. M., Hill, R. G.

“…Calcitonin gene‐related peptide (CGRP), adrenomedullin (ADM), amylin and calcitonin (CT) are structurally and functionally related neuropeptides. It has…”
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Sphingosine 1‐phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma by Ammit, Alaina J., Hastie, Annette T., Edsall, Lisa C., Hoffman, Rebecca K., Amrani, Yassine, Krymskaya, Vera P., Kane, Sibyl A., Peters, Stephen P., Penn, Raymond B., Spiegel, Sarah, Panettieri, Reynold A.

“…ABSTRACT Asthma is characterized by airway inflammation, remodeling, and hyperresponsiveness to contractile stimuli that promote airway constriction and…”
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Canine discrimination of ovarian cancer through volatile organic compounds by Kane, S.A., Lee, Y.E., Essler, J.L., Mallikarjun, A., Preti, G., Plymouth, V.L., Verta, A., DeAngelo, A., Otto, C.M.

“…Ovarian cancer has a high mortality rate due to its unclear symptomology and the lack of precise early detection tools. If detected in the first stage, over…”
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Harmful algal bloom toxins alter c-Fos protein expression in the brain of killifish, Fundulus heteroclitus by Salierno, J.D., Snyder, N.S., Murphy, A.Z., Poli, M., Hall, S., Baden, D., Kane, A.S.

“…The immediate early gene c-fos, and its protein product c-Fos, are known to be induced in neurons of mammals and fish as a result of neuronal stimulation. The…”
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Quantitative movement analysis of social behavior in mummichog, Fundulus heteroclitus by Salierno, J. D., Gipson, G. T., Kane, A. S.

“…Group living among fishes has notable biological significance for individual well being and survival. However, group swimming dynamics have been historically…”
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Survey and genetic characterization of Vibrio cholerae in Apalachicola Bay, Florida (2012–2014) by Fang, L., Ginn, A.M., Harper, J., Kane, A.S., Wright, A.C.

“…Aims A small outbreak of gastroenteritis in 2011 in Apalachicola Bay, FL was attributed to consumption of raw oysters carrying Vibrio cholerae serotype O75. To…”
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Altered c-Fos expression demonstrates neuronal stress in mummichog, Fundulus heteroclitus, exposed to Pfiesteria shumwayae and Chaetoceros concavicornis by SALIERNO, J. D, SHIELDS, J. D, MURPHY, A. Z, HOFFMAN, G. E, KANE, A. S

“…To better understand sublethal effects of harmful algal blooms (HABs) on fish, mummichog, Fundulus heteroclitus (L.), were exposed in the laboratory to…”
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Myxosporean plasmodial infection associated with ulcerative lesions in young-of-the-year Atlantic menhaden in a tributary of the Chesapeake Bay, and possible links to Kudoa clupeidae by REIMSCHUESSEL, R, GIESEKER, C. M, DRISCOLL, C, BAYA, A, KANE, A. S, BLAZER, V. S, EVANS, J. J, KENT, M. L, MORAN, J. D. W, POYNTON, S. L

“…Ulcers in Atlantic menhaden Brevoortia tyrannus (Latrobe) (Clupeidae), observed along the USA east coast, have been attributed to diverse etiologies including…”
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Microbubbles are detected prior to larger bubbles following decompression by Swan, J G, Wilbur, J C, Moodie, K L, Kane, S A, Knaus, D A, Phillips, S D, Beach, T L, Fellows, A M, Magari, P J, Buckey, J C

“…Using dual-frequency ultrasound (DFU), microbubbles (<10 μm diameter) have been detected in tissue following decompression. It is not known if these…”
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Noise-induced stress response and hearing loss in goldfish (Carassius auratus) by Smith, Michael E, Kane, Andrew S, Popper, Arthur N

“…Fishes are often exposed to environmental sounds such as those associated with shipping, seismic experiments, sonar and/or aquaculture pump systems. While…”
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Pathology of fathead minnows ( Pimephales promelas) exposed to chlorine dioxide and chlorite by Yonkos, L.T, Fisher, D.J, Wright, D.A, Kane, A.S

“…Fathead minnows ( Pimephales promelas) were exposed to the biocide chlorine dioxide (0.13 and 0.19 mg l −1) for up to 12 h and to its primary decomposition…”
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Pathogenicity of Mycobacterium fortuitum and Mycobacterium smegmatis to goldfish, Carassius auratus by Talaat, Adel M, Trucksis, Michele, Kane, Andrew S, Reimschuessel, Renate

“…Despite the ubiquitous presence of atypical mycobacteria in the environment and the potential risk of infection in humans and animals, the pathogenesis of…”
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New Nephron Development in Goldfish (Carassius auratus) Kidneys Following Repeated Gentamicin-Induced Nephrotoxicosis by Salice, Christopher J., Rokous, Judith South, Kane, Andrew S., Reimschuessel, Renate

“…Renal development in mammalian kidneys can only be studied in embryonic animals. Hence, research in this area is hampered by the need to maintain pregnant…”
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Screen-printed tyrosinase-containing electrodes for the biosensing of enzyme inhibitors by Wang, Joseph, Nascimento, Valberes B., Kane, Stephen A., Rogers, Kim, Smyth, Malcom R., Angnes, Lucio

“…Disposable amperometric inhibition biosensors have been microfabricated by screen printing a tyrosinase-containing carbon ink. The decrease in the substrate…”
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