Search Results - "Kandpal, Manoj"

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle by Wang, Gang, Biswas, Anup K., Ma, Wanchao, Kandpal, Manoj, Coker, Courtney, Grandgenett, Paul M., Hollingsworth, Michael A., Jain, Rinku, Tanji, Kurenai, Lόpez-Pintado, Sara, Borczuk, Alain, Hebert, Doreen, Jenkitkasemwong, Supak, Hojyo, Shintaro, Davuluri, Ramana V., Knutson, Mitchell D., Fukada, Toshiyuki, Acharyya, Swarnali

“…Patients with metastatic cancer experience a severe loss of skeletal muscle mass and function known as cachexia. Cachexia is associated with poor prognosis and…”
Get full text

Immune landscapes associated with different glioblastoma molecular subtypes by Martinez-Lage, Maria, Lynch, Timothy M, Bi, Yingtao, Cocito, Carolina, Way, Gregory P, Pal, Sharmistha, Haller, Josephine, Yan, Rachel E, Ziober, Amy, Nguyen, Aivi, Kandpal, Manoj, O'Rourke, Donald M, Greenfield, Jeffrey P, Greene, Casey S, Davuluri, Ramana V, Dahmane, Nadia

“…Recent work has highlighted the tumor microenvironment as a central player in cancer. In particular, interactions between tumor and immune cells may help drive…”
Get full text

Fluorescence and Piezoresistive Cantilever Sensing of Trinitrotoluene by an Upper-Rim Tetrabenzimidazole Conjugate of Calix[4]arene and Delineation of the Features of the Complex by Molecular Dynamics by Kandpal, Manoj, Bandela, Anil Kumar, Hinge, Vijaya Kumar, Rao, V. Ramgopal, Rao, Chebrolu Pulla

“…A new benzimidazole-functionalized calix[4]arene receptor (R) was synthesized and characterized. The receptor R shows better selectivity toward trinitrotoluene…”
Get full text

FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer by Tai, Yifan, Chow, Angela, Han, Seoyoung, Coker, Courtney, Ma, Wanchao, Gu, Yifan, Estrada Navarro, Valeria, Kandpal, Manoj, Hibshoosh, Hanina, Kalinsky, Kevin, Manova-Todorova, Katia, Safonov, Anton, Walsh, Elaine M, Robson, Mark, Norton, Larry, Baer, Richard, Merghoub, Taha, Biswas, Anup K, Acharyya, Swarnali

“…Acquired resistance to PARP inhibitors (PARPi) remains a treatment challenge for BRCA 1/2-mutant breast cancer that drastically shortens patient survival…”
Get full text

Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing by Ideozu, Justin E, Rangaraj, Vittobai, Abdala-Valencia, Hiam, Zhang, Xi, Kandpal, Manoj, Sala, Marc A, Davuluri, Ramana V, Levy, Hara

“…In cystic fibrosis (CF), impaired immune cell responses, driven by the dysfunctional CF transmembrane conductance regulator (CFTR) gene, may determine the…”
Get full text

Building an infrastructure to support the development, conduct, and reporting of informative clinical studies: The Rockefeller University experience by Kost, Rhonda G, Devine, Rita K, Fernands, Mark, Gottesman, Riva, Kandpal, Manoj, MacArthur, Robert B, O'Sullivan, Barbara, Romanick, Michelle, Ronning, Andrea, Schlesinger, Sarah, Tobin, Jonathan N, Vaughan, Roger, Neville-Williams, Maija, Krueger, James G, Coller, Barry S

“…Clinical trials are a vital component of translational science, providing crucial information on the efficacy and safety of new interventions and forming the…”
Get full text

Donor‐derived cell‐free DNA levels predict graft injury in liver transplant recipients by Levitsky, Josh, Kandpal, Manoj, Guo, Kexin, Kleiboeker, Steve, Sinha, Rohita, Abecassis, Michael

“…Donor‐derived cell‐free DNA (dd‐cfDNA) has been evaluated as a rejection marker in organ transplantation. This study sought to assess the utility of dd‐cfDNA…”
Get full text

FTO-Dependent N 6 -Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling by Huang, Hao, Wang, Yinu, Kandpal, Manoj, Zhao, Guangyuan, Cardenas, Horacio, Ji, Yanrong, Chaparala, Anusha, Tanner, Edward J, Chen, Jianjun, Davuluri, Ramana V, Matei, Daniela

“…-Methyladenosine (m A) is the most abundant modification of mammalian mRNAs. RNA methylation fine tunes RNA stability and translation, altering cell fate. The…”
Get full text

Characterization and detection of cardiac Troponin-T protein by using ‘aptamer’ mediated biofunctionalization of ZnO thin-film transistor by Agarwal, Dilip Kumar, Kandpal, Manoj, Surya, Sandeep G.

“…[Display omitted] •Biofunctionalization of DNA aptamer against cardiac marker protein Troponin-T on ZnO channel surface.•Characterization of biofunctionalized…”
Get full text

Prediction of Liver Transplant Rejection With a Biologically Relevant Gene Expression Signature by Levitsky, Josh, Kandpal, Manoj, Guo, Kexin, Zhao, Lihui, Kurian, Sunil, Whisenant, Thomas, Abecassis, Michael

“…Noninvasive biomarkers distinguishing early immune activation before acute rejection (AR) could more objectively inform immunosuppression management in liver…”
Get full text

415.6: Exploring Cell-Specific Mechanisms of Ischemia/Reperfusion Injury Mediated Reactivation of Cytomegalovirus From Latency in the Orthotopic Mouse Lung Transplantation by VanOsdol, Luke A, Kandpal, Manoj, Han, Shuling, Wang, Jiao-Jing, Qiu, Longhui, Zhang, Zheng

Get full text

A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma by Kumthekar, Priya, Ko, Caroline H, Paunesku, Tatjana, Dixit, Karan, Sonabend, Adam M, Bloch, Orin, Tate, Matthew, Schwartz, Margaret, Zuckerman, Laura, Lezon, Ray, Lukas, Rimas V, Jovanovic, Borko, McCortney, Kathleen, Colman, Howard, Chen, Si, Lai, Barry, Antipova, Olga, Deng, Junjing, Li, Luxi, Tommasini-Ghelfi, Serena, Hurley, Lisa A, Unruh, Dusten, Sharma, Nitya V, Kandpal, Manoj, Kouri, Fotini M, Davuluri, Ramana V, Brat, Daniel J, Muzzio, Miguel, Glass, Mitchell, Vijayakumar, Vinod, Heidel, Jeremy, Giles, Francis J, Adams, Ann K, James, C David, Woloschak, Gayle E, Horbinski, Craig, Stegh, Alexander H

“…Glioblastoma (GBM) is one of the most difficult cancers to effectively treat, in part because of the lack of precision therapies and limited therapeutic access…”
Get more information

Machine Learning and Bioinformatics Approaches to Discover Urine Gene Expression Biomarkers for Kidney Transplant Rejection: PO2178 by Kandpal, Manoj, Keslar, Karen S., Friedewald, John J., Fairchild, Robert L.

Get full text

Development and clinical validity of a novel blood‐based molecular biomarker for subclinical acute rejection following kidney transplant by Friedewald, John J., Kurian, Sunil M., Heilman, Raymond L., Whisenant, Thomas C., Poggio, Emilio D., Marsh, Christopher, Baliga, Prabhakar, Odim, Jonah, Brown, Merideth M., Ikle, David N., Armstrong, Brian D., charette, jane I., Brietigam, Susan S., Sustento‐Reodica, Nedjema, Zhao, Lihui, Kandpal, Manoj, Salomon, Daniel R., Abecassis, Michael M.

“…Noninvasive biomarkers are needed to monitor stable patients after kidney transplant (KT), because subclinical acute rejection (subAR), currently detectable…”
Get full text

Discovery and validation of a novel blood‐based molecular biomarker of rejection following liver transplantation by Levitsky, Josh, Asrani, Sumeet K., Schiano, Thomas, Moss, Adyr, Chavin, Kenneth, Miller, Charles, Guo, Kexin, Zhao, Lihui, Kandpal, Manoj, Bridges, Nancy, Brown, Merideth, Armstrong, Brian, Kurian, Sunil, Demetris, Anthony J., Abecassis, Michael

“…Noninvasive biomarker profiles of acute rejection (AR) could affect the management of liver transplant (LT) recipients. Peripheral blood was collected…”
Get full text

Experimental study of chromium oxide thin films as an intermediate layer for Pt-based temperature sensor applications by Kandpal, Manoj, Shirhatti, Vijay, Singh, Jaspreet, Sontakke, British Ashok, Jejusaria, Alok, Arora, Satay Pal Singh, Singh, Surinder

“…This paper reports, the impact of high-temperature annealing on temperature coefficient of resistance (TCR) of platinum thin films, by using chromium oxide as…”
Get full text

Abstract 2449: A novel function of FTO in ovarian cancer stem cells through m6A RNA demethylation by Huang, Hao, Wang, Yinu, Kandpal, Manoj, Zhao, Guangyuan, Cardenas, Horacio, Ji, Yanrong, Tanner, Edward, Chen, Jianjun, Davuluri, Ramana, Matei, Daniela

“…Abstract Introduction: N6-Methyladenosine (m6A) is the most abundant internal modification in mammalian messenger RNAs (mRNAs). Although previous studies have…”
Get full text

Low Cost, Large Area, Flexible Graphene Nanocomposite Films for Energy Harvesting Applications by Kandpal, Manoj, Palaparthy, Vijay, Tiwary, Nikhilendu, Rao, V. Ramgopal

“…In this paper, we report a robust and a low-cost spin coating approach for fabrication of large area flexible piezoelectric nanocomposite generator device for…”
Get full text

Residual stress compensated silicon nitride microcantilever array with integrated poly-Si piezoresistor for gas sensing applications by Kandpal, Manoj, Behera, Satya Narayan, Singh, Jaspreet, Palaparthy, Vijay, Singh, Surinder

“…This work reports a novel method of microfabrication for silicon nitride based piezoresistive microcantilever device, to minimize the residual stress induced…”
Get full text

Abstract B74: Identification of prognostic molecular subtypes of ovarian serous cystadenocarcinoma by isoform-level gene expression analysis by Shilpi, Arunima, Seagle, Brandon L., Kandpal, Manoj, Shahabi, Shohreh, Davuluri, Ramana V.

“…Abstract Characterization of molecular aberrations in ovarian serous cystadenocarcinoma (OVSC) is highly crucial for developing precision medicine approaches…”
Get full text