Search Results - "Kandell, Wendy"

An immunoproteomic approach to characterize the CAR interactome and signalosome by Ramello, Maria C, Benzaïd, Ismahène, Kuenzi, Brent M, Lienlaf-Moreno, Maritza, Kandell, Wendy M, Santiago, Daniel N, Pabón-Saldaña, Mibel, Darville, Lancia, Fang, Bin, Rix, Uwe, Yoder, Sean, Berglund, Anders, Koomen, John M, Haura, Eric B, Abate-Daga, Daniel

“…Adoptive transfer of T cells that express a chimeric antigen receptor (CAR) is an approved immunotherapy that may be curative for some hematological cancers…”
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MicroRNA-155 governs SHIP-1 expression and localization in NK cells and regulates subsequent infiltration into murine AT3 mammary carcinoma by Kandell, Wendy M, Donatelli, Sarah S, Trinh, Thu Le, Calescibetta, Alexandra R, So, Tina, Tu, Nhan, Gilvary, Danielle L, Chen, Xianghong, Cheng, Pingyan, Adams, William A, Chen, Yin-Kai, Liu, Jinhong, Djeu, Julie Y, Wei, Sheng, Eksioglu, Erika A

“…NK cell migration and activation are crucial elements of tumor immune surveillance. In mammary carcinomas, the number and function of NK cells is diminished,…”
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Fighting Cancer with Mathematics and Viruses by Santiago, Daniel N, Heidbuechel, Johannes P W, Kandell, Wendy M, Walker, Rachel, Djeu, Julie, Engeland, Christine E, Abate-Daga, Daniel, Enderling, Heiko

“…After decades of research, oncolytic virotherapy has recently advanced to clinical application, and currently a multitude of novel agents and combination…”
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Immune evasion by TGFβ-induced miR-183 repression of MICA/B expression in human lung tumor cells by Trinh, Thu Le, Kandell, Wendy M., Donatelli, Sarah S., Tu, Nhan, Tejera, Melba M., Gilvary, Danielle L., Eksioglu, Erika A., Burnette, Alexis, Adams, William A., Liu, Jinhong, Teer, Jamie K., Djeu, Julie Y., Coppola, Domenico, Wei, Sheng

“…Immune escape is a hallmark of cancer. In human lung cancer, we have identified a unique microRNA (miR)-based pathway employed by tumor cells to repress…”
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CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies by Trinh, ThuLe, Adams, William A., Calescibetta, Alexandra, Tu, Nhan, Dalton, Robert, So, Tina, Wei, Max, Ward, Grace, Kostenko, Elena, Christiansen, Sean, Cen, Ling, McLemore, Amy, Reed, Kayla, Whitting, Junmin, Gilvary, Danielle, Blanco, Neale Lopez, Segura, Carlos Moran, Nguyen, Jonathan, Kandell, Wendy, Chen, Xianghong, Cheng, Pingyan, Wright, Gabriela M., Cress, W. Douglas, Liu, Jinghong, Wright, Kenneth L., Wei, Sheng, Eksioglu, Erika A.

“…Advances in the understanding of the tumor microenvironment have led to development of immunotherapeutic strategies, such as chimeric antigen receptor T cells…”
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S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes by Cheng, Pinyang, Eksioglu, Erika A., Chen, Xianghong, Kandell, Wendy, Le Trinh, Thu, Cen, Ling, Qi, Jin, Sallman, David A., Zhang, Yu, Tu, Nhan, Adams, William A., Zhang, Chunze, Liu, Jinhong, Cleveland, John L., List, Alan F., Wei, Sheng

“…Myelodysplastic syndromes (MDS) are characterized by dysplastic and ineffective hematopoiesis that can result from aberrant expansion and activation of…”
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S100A9 Contributes to T Cell Dysfunction through Its Interaction with RAGE in MDS by Kandell, Wendy, Trinh, Thu Le, Chen, Xianghong, Cheng, Pingyan, Gilvary, Danielle, Chen, Yin-Kai, Calescibetta, Alexandra, Eksioglu, Erika Adriana, List, Alan F., Wei, Sheng

“…We have previously reported that the overexpression of S100A9 drives the development of Myelodysplastic Syndrome (MDS) through expansion of Myeloid Derived…”
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Dysregulation of Splicing Patterns in MDS Induced By the S100A9/Fto Axis by Eksioglu, Erika Adriana, Cen, Ling, Chen, Xianghong, Cheng, Pingyan, Wright, Kenneth, Trinh, Thu Le, Gilvary, Danielle, Kandell, Wendy, Liu, Jinhong, Chen, Yin-Kai, McLemore, Amy F, Calescibetta, Alexandra, Cleveland, John, List, Alan F., Wei, Sheng

“…We previously reported that S100A9 promotes ineffective hematopoiesis and the development of MDS in a feed forward age-dependent fashion. Nonetheless, the…”
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Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment by Kandell, Wendy Michelle

“…The immune system plays a dynamic role in cancer progression. The theory of immunoediting suggests that the relationship between the tumor cell and the immune…”
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