Search Results - "Kandar, Bojidar M."

TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects by Haderski, Gary J, Kandar, Bojidar M, Brackett, Craig M, Toshkov, Ilia M, Johnson, Christopher P, Paszkiewicz, Geraldine M, Natarajan, Venkatesh, Gleiberman, Anatoli S, Gudkov, Andrei V, Burdelya, Lyudmila G

“…Tumor necrosis factor alpha (TNF) is capable of inducing regression of solid tumors. However, TNF released in response to Toll-like receptor 4 (TLR4)…”
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Signaling through TLR5 mitigates lethal radiation damage by neutrophil-dependent release of MMP-9 by Brackett, Craig M., Greene, Kellee F., Aldrich, Alyssa R., Trageser, Nicholas H., Pal, Srabani, Molodtsov, Ivan, Kandar, Bojidar M., Burdelya, Lyudmila G., Abrams, Scott I., Gudkov, Andrei V.

“…Acute radiation syndrome (ARS) is a major cause of lethality following radiation disasters. A TLR5 agonist, entolimod, is among the most powerful experimental…”
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Toll-like Receptor-5 Agonist Entolimod Broadens the Therapeutic Window of 5-Fluorouracil by Reducing Its Toxicity to Normal Tissues in Mice by Kandar, Bojidar M

“…Myelosuppression and gastrointestinal damage are common side effects of cancer treatment limiting efficacy of DNA-damaging chemotherapeutic drugs. The…”
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