Search Results - "Kancheva, Lyudmila"

Steroid profiling in pregnancy: A focus on the human fetus by Hill, Martin, Pašková, Andrea, Kančeva, Radmila, Velíková, Marta, Kubátová, Jana, Kancheva, Lyudmila, Adamcová, Karolína, Mikešová, Michaela, Žižka, Zdeněk, Koucký, Michal, Šarapatková, Hana, Kačer, Viktor, Matucha, Petr, Meloun, Milan, Pařízek, Antonín

“…•Steroid profiling and physiological relevance of bioactive steroids in pregnancy.•Risk of reproductive disorders, misbalance of HPA in further stages of human…”
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Steroid metabolome in fetal and maternal body fluids in human late pregnancy by Hill, Martin, Pařízek, Antonín, Cibula, David, Kancheva, Radmila, Jirásek, Jan Evangelista, Jirkovská, Marie, Velíková, Marta, Kubátová, Jana, Klímková, Michaela, Pašková, Andrea, Žižka, Zdeněk, Kancheva, Lyudmila, Kazihnitková, Hana, Zamrazilová, Ludmila, Stárka, Luboslav

“…Despite the extensive research during the last six decades the fundamental questions concerning the role of steroids in the initiation of human parturition and…”
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Serum Profiles of Free and Conjugated Neuroactive Pregnanolone Isomers in Nonpregnant Women of Fertile Age by Havlíková, Helena, Hill, Martin, Kancheva, Lyudmila, Vrbíková, Jana, Pouzar, Vladimír, Černý, Ivan, Kancheva, Radmila, Stárka, Luboslav

“…Background: Pregnanolone isomers (PI) with a hydroxy group in the 3α-position are neuroinhibitors operating via positive modulation of GABAA receptors. The…”
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Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy by Kancheva, Radmila, Hill, Martin, Cibula, David, Včeláková, Helena, Kancheva, Lyudmila, Vrbíková, Jana, Fait, Tomáš, Pařízek, Antonín, Stárka, Luboslav

“…Pregnanolone isomers (PIs) and their polar conjugates (PICs) modulate ionotropic receptors such as γ-aminobutyric acid or pregnane X receptors. Besides, brain…”
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Nightmares and suicide: predicting risk in depression by Marinova, Petra, Koychev, Ivan, Laleva, Lili, Kancheva, Lyudmila, Tsvetkov, Milen, Bilyukov, Radoslav, Vandeva, Diana, Felthouse, Alan, Koychev, Georgi

“…There is growing evidence of an association of a number of subjective and objective sleep parameters (especially nightmares) and elevated suicidal risk in…”
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Peripheral neuroactive steroids may be as good as the steroids in the cerebrospinal fluid for the diagnostics of CNS disturbances by Kancheva, Radmila, Hill, Martin, Novák, Zdeněk, Chrastina, Jan, Velíková, Marta, Kancheva, Lyudmila, Říha, Ivo, Stárka, Luboslav

“…To compare the predictivity of the neuroactive steroids in the cerebrospinal fluid and peripheral blood for the diagnostics of CNS disturbances, eighteen…”
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Circulating levels of pregnanolone isomers during the third trimester of human pregnancy by Hill, Martin, Cibula, David, Havlíková, Helena, Kancheva, Lyudmila, Fait, Tomáš, Kancheva, Radmila, Pařízek, Antonín, Stárka, Luboslav

“…This study addresses the question of whether changes in the biosynthesis and metabolism of neuroactive pregnanolone isomers (PIs) might participate in the…”
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The steroid metabolome in lamotrigine-treated women with epilepsy by Hill, Martin, Vrbíková, Jana, Zárubová, Jana, Kancheva, Radmila, Velíková, Marta, Kancheva, Lyudmila, Kubátová, Jana, Dušková, Michaela, Marusič, Petr, Pařízek, Antonín, Stárka, Luboslav

“…[Display omitted] ► Evaluation of circulating steroids in fertile lamotrigine-treated women with epilepsy. ► Patients exhibit higher levels of…”
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Effects of valproate and carbamazepine monotherapy on neuroactive steroids, their precursors and metabolites in adult men with epilepsy by Hill, Martin, Zárubová, Jana, Marusič, Petr, Vrbíková, Jana, Velíková, Marta, Kancheva, Radmila, Kancheva, Lyudmila, Kubátová, Jana, Dušková, Michaela, Zamrazilová, Ludmila, Kazihnitková, Hana, Šimůnková, Kateřina, Stárka, Luboslav

“…Only limited data is available concerning the role of unconjugated Δ 5 C19-steroids and almost no data exists regarding the neuroactive C21 and C19…”
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Neuroactive Pregnanolone Isomers during Pregnancy by Pařízek, Antonín, Hill, Martin, Kancheva, Radmila, Havlíková, Helena, Kancheva, Lyudmila, Cindr, Josef, Pašková, Andrea, Pouzar, Vladimír, Černý, Ivan, Drbohlav, Pavel, Hájek, Zdeněk, Stárka, Luboslav

“…The pregnanolone isomers (PI) allopregnanolone (3α-hydroxy-5α-pregnan-20-one), pregnanolone (3α-hydroxy-5β-pregnan-20-one), isopregnanolone…”
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The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3β,17β-androstenediol, and testosterone in human serum using gas chromatography–mass spectrometry by Hill, Martin, Havlíková, Helena, Vrbíková, Jana, Kancheva, Radmila, Kancheva, Lyudmila, Pouzar, Vladimír, Černý, Ivan, Stárka, Luboslav

“…7-Hydroxy-metabolites of dehydroepiandrosterone (DHEA) and 3β,17β-androstenediol (AD) possess immunomodulatory and neuroprotective properties; therefore, the…”
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Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction by Hill, Martin, Popov, Petr, Havlíková, Helena, Kancheva, Lyudmila, Vrbíková, Jana, Kancheva, Radmila, Pouzar, Vladimír, Černý, Ivan, Stárka, Luboslav

“…Long-term alcohol consumption results in menstrual irregularities due to the inhibition of progesterone secretion. Some progesterone metabolites, including…”
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The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3beta,17beta-androstenediol, and testosterone in human serum using gas chromatography-mass spectrometry by Hill, Martin, Havlíková, Helena, Vrbíková, Jana, Kancheva, Radmila, Kancheva, Lyudmila, Pouzar, Vladimír, Cerný, Ivan, Stárka, Luboslav

“…7-Hydroxy-metabolites of dehydroepiandrosterone (DHEA) and 3beta,17beta-androstenediol (AD) possess immunomodulatory and neuroprotective properties; therefore,…”
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Reinstatement of Serum Pregnanolone Isomers and Progesterone During Alcohol Detoxification Therapy in Premenopausal Women by Hill, Martin, Popov, Petr, Havlikova, Helena, Kancheva, Lyudmila, Vrbikova, Jana, Meloun, Milan, Kancheva, Radmila, Cibula, David, Pouzar, Vladimir, Cerny, Ivan, Starka, Luboslav

“…Background: Alcohol abuse is associated with menstrual irregularities related to the inhibition of progesterone secretion involved in regulation of the…”
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NIGHTMARES AND SUICIDE: PREDICTING RISK IN DEPRESSION by Marinova, Petra, Koychev, Ivan, Laleva, Lili, Kancheva, Lyudmila, Tsvetkov, Milen, Bilyukov, Radoslav, Vandeva, Diana, Felthouse, Alan, Koychev, Georgi

“…Background: There is growing evidence of an association of a number of subjective and objective sleep parameters (especially nightmares) and elevated suicidal…”
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