Search Results - "Kanazawa, Yoshito"
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Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5
Published in Nature communications (02-06-2020)“…Currently, there are no treatments for Alport syndrome, which is the second most commonly inherited kidney disease. Here we report the development of an…”
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The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced Amyloid β Binding Antibodies on Cynomolgus Monkeys and Guinea Pigs
Published in Journal of immunology research (01-01-2015)“…The reduction of brain amyloid beta (Aβ) peptides by anti-Aβ antibodies is one of the possible therapies for Alzheimer’s disease. We previously reported that…”
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Protective Effect of DY-9760e, a Calmodulin Antagonist, against Neuronal Cell Death
Published in Biological & pharmaceutical bulletin (01-11-2004)“…An excessive elevation of intracellular Ca2+ levels is known to play a key role in the pathological events following cerebral ischemia. DY-9760e,…”
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DY-9760e, a Calmodulin Antagonist, Reduces Brain Damage after Permanent Focal Cerebral Ischemia in Cats
Published in Biological & Pharmaceutical Bulletin (01-04-2005)“…DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate), a calmodulin…”
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PRODUCTION OF ANTI-Aβ ANTIBODY BY THE PEPTIDE VACCINATION WITHOUT ANY ADJUVANT IN EXPERIMENTAL ANIMALS
Published in Alzheimer's & dementia (01-07-2014)Get full text
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P2‐395: PRODUCTION OF ANTI‐Aβ ANTIBODY BY THE PEPTIDE VACCINATION WITHOUT ANY ADJUVANT IN EXPERIMENTAL ANIMALS
Published in Alzheimer's & dementia (01-07-2014)Get full text
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A novel method for enhancement of peptide vaccination utilizing T-cell epitopes from conventional vaccines
Published in Vaccine (01-03-2013)“…Highlights ► We designed the vaccine peptide including the T-cell epitope from diphtheria toxoid. ► Pre-immunization of diphtheria vaccine enhanced…”
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A novel method for enhancement of peptide vaccination utilizing T-cell epitopes from conventional vaccines
Published in Alzheimer's & dementia (01-07-2013)Get full text
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P2–396: A novel method for enhancement of peptide vaccination utilizing T‐cell epitopes from conventional vaccines
Published in Alzheimer's & dementia (01-07-2013)Get full text
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The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced Amyloid [beta] Binding Antibodies on Cynomolgus Monkeys and Guinea Pigs
Published in Journal of immunology research (01-01-2015)“…The reduction of brain amyloid beta (Aβ) peptides by anti-Aβ antibodies is one of the possible therapies for Alzheimer's disease. We previously reported that…”
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P2–395: Effect of a novel beta‐amyloid peptide vaccine on brain beta‐amyloid deposition in Tg2576 mice
Published in Alzheimer's & dementia (01-07-2013)Get full text
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Effect of a novel beta-amyloid peptide vaccine on brain beta-amyloid deposition in Tg2576 mice
Published in Alzheimer's & dementia (01-07-2013)Get full text
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Involvement of calmodulin in neuronal cell death
Published in Brain research (14-04-2006)“…A large body of evidence indicates that disturbances of Ca 2+ homeostasis may be a causative factor in the neurotoxicity following cerebral ischemia. However,…”
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