Search Results - "Kanayama, Yousuke"
-
1
PET imaging of neural activity, β-amyloid, and tau in normal brain aging
Published in European journal of nuclear medicine and molecular imaging (01-11-2021)“…Normal brain aging is commonly associated with neural activity alteration, β-amyloid (Aβ) deposition, and tau aggregation, driving a progressive cognitive…”
Get full text
Journal Article -
2
Neural correlates of beneficial effects of young plasma treatment in aged mice: PET-SPM analyses and neuro-behavioural/molecular biological studies
Published in European journal of nuclear medicine and molecular imaging (01-04-2022)“…Purpose To investigate the in vivo neurofunctional changes and therapeutic effects of young blood plasma (YBP) in aged mice, as well as the molecular…”
Get full text
Journal Article -
3
Visualization and Quantitative Assessment of the Brain Distribution of Insulin through Nose-to-Brain Delivery Based on the Cell-Penetrating Peptide Noncovalent Strategy
Published in Molecular pharmaceutics (07-03-2016)“…Our recent work suggested that intranasal coadministration with the cell-penetrating peptide (CPP) penetratin increased the brain distribution of the peptide…”
Get full text
Journal Article -
4
Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography
Published in Journal of controlled release (17-08-2010)“…Molecular imaging technique by use of positron emission tomography (PET) is a noninvasive tool that allows one to quantitatively analyze the function of…”
Get full text
Journal Article -
5
Demonstration of in-vivo Multi-Probe Tracker Based on a Si/CdTe Semiconductor Compton Camera
Published in IEEE transactions on nuclear science (01-02-2012)“…By using a prototype Compton camera consisting of silicon (Si) and cadmium telluride (CdTe) semiconductor detectors, originally developed for the ASTRO-H…”
Get full text
Journal Article -
6
Identification and characterization of the zosA gene involved in copper uptake in Bacillus subtilis 168
Published in Bioscience, biotechnology, and biochemistry (03-03-2016)“…dl-Penicillamine, a copper-specific metal chelator, remarkably suppressed the growth of Bacillus subtilis 168 when added to a synthetic medium under Cu 2+…”
Get full text
Journal Article -
7
Exploration of target molecules for molecular imaging of inflammatory bowel disease
Published in Biochemical and biophysical research communications (08-07-2011)“…► 18F-FDG PET could discriminate each inflamed area of IBD model mice clearly. ► 18F-FDG PET could not discriminate the difference of pathogenic mechanism. ►…”
Get full text
Journal Article -
8
64Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients
Published in EJNMMI research (12-03-2015)“…Background The purpose of this study was to determine whether brain metastases from HER2-positive breast cancer could be detected noninvasively using positron…”
Get full text
Journal Article -
9
Multitracer screening: brain delivery of trace elements by eight different administration methods
Published in Biometals (01-12-2005)“…Trace elements are closely associated with the normal functioning of the brain. Therefore, it is important to determine how trace elements enter, accumulate,…”
Get full text
Journal Article -
10
Axonal transport of rubidium and thallium in the olfactory nerve of mice
Published in Nuclear medicine and biology (01-07-2005)“…Following intranasal administration of radioactive 86Rb + and 201Tl + in mice, we observed this direct transport via the olfactory nerve pathway. The 86RbCl…”
Get full text
Journal Article -
11
211 At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics
Published in Chemical science (Cambridge) (21-02-2019)“…α-Emission radiotherapeutics has potential to be one of most effective cancer therapeutics. Herein, we report a facile synthesis of an At-labeled…”
Get full text
Journal Article -
12
211At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics
Published in Chemical science (Cambridge) (21-02-2019)“…α-Emission radiotherapeutics has potential to be one of most effective cancer therapeutics. Herein, we report a facile synthesis of an 211At-labeled…”
Get full text
Journal Article -
13
211At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04747b
Published in Chemical science (Cambridge) (21-12-2018)“…A facile synthesis of an 211 At-labeled immunoconjugate for α-emission therapy was achieved based on a one-pot three-component double click method. α-Emission…”
Get full text
Journal Article -
14
Visualization of HER2-specific breast cancer intratumoral heterogeneity using 64Cu-DOTA-trastuzumab PET
Published in European journal of nuclear medicine and molecular imaging (01-11-2017)Get full text
Journal Article -
15
Noninvasive Imaging of Dendrimer‐Type N‐Glycan Clusters: In Vivo Dynamics Dependence on Oligosaccharide Structure
Published in Angewandte Chemie (International ed.) (25-10-2010)“…Body image: Self‐activating Huisgen 1,3‐dipolar cycloaddition and 6π azaelectrocyclization of lysine‐based dendrimers (see picture) enable the in vivo dynamics…”
Get full text
Journal Article -
16
(64)Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients
Published in EJNMMI research (2015)“…The purpose of this study was to determine whether brain metastases from HER2-positive breast cancer could be detected noninvasively using positron emission…”
Get full text
Journal Article -
17
CdTe-DSD SPECT-I: An Ultrahigh-Resolution Multi-Isotope Tomographic Imager for Mice
Published in IEEE transactions on radiation and plasma medical sciences (01-11-2023)“…Multi-isotope imaging in vivo is an appealing molecular imaging approach that provides extensive information about molecular pathways that cannot be accessed…”
Get full text
Journal Article -
18
Simultaneous visualization of multiple radionuclides in vivo
Published in Nature biomedical engineering (01-05-2022)“…The insufficient energy and spatial resolutions of radionuclide imaging with conventional scintillation detectors restrict the visualization of multiple…”
Get full text
Journal Article -
19
CdTe-DSD SPECT-I: an Ultra-High-Resolution Multi-Isotope Tomographic Imager for Mice
Published in IEEE transactions on radiation and plasma medical sciences (03-07-2023)“…Multi-isotope imaging in vivo is an appealing molecular imaging approach that provides extensive information about molecular pathways that cannot be accessed…”
Get full text
Journal Article -
20
Molecular imaging using PET for breast cancer
Published in Breast cancer (Tokyo, Japan) (01-01-2016)“…Molecular imaging can visualize the biological processes at the molecular and cellular levels in vivo using certain tracers for specific molecular targets…”
Get full text
Journal Article