Search Results - "Kanashiro, M. M."

Ablation of the N terminus of cardiac essential light chain promotes the super‐relaxed state of myosin and counteracts hypercontractility in hypertrophic cardiomyopathy mutant mice by Sitbon, Yoel H., Kazmierczak, Katarzyna, Liang, Jingsheng, Yadav, Sunil, Veerasammy, Melanie, Kanashiro‐Takeuchi, Rosemeire M., Szczesna‐Cordary, Danuta

“…In this study, we focus on the molecular mechanisms associated with the A57G (Ala57‐to‐Gly57) mutation in myosin essential light chains (ELCs), found to cause…”
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Exploring the magnitude and drivers of the double burden of malnutrition at maternal and dyad levels in peri-urban Peru: A cross-sectional study of low-income mothers, infants and young children by Pradeilles, Rebecca, Landais, Edwige, Pareja, Rossina, Eymard-Duvernay, Sabrina, Markey, Oonagh, Holdsworth, Michelle, Rousham, Emily K, M Creed-Kanashiro, Hilary

“…Multiple forms of malnutrition coexist in Peru, especially in peri-urban areas and poor households. We investigated the magnitude of, and the contribution of,…”
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Identifying priority double-duty actions to tackle the double burden of malnutrition in infants and young children in Peru: Assessment and prioritisation of government actions by national experts by Huayta, Violeta Magdalena Rojas, Pradeilles, Rebecca, Creed-Kanashiro, Hilary M, Rousham, Emily, Delgado, Doris, Pareja, Rossina, Landais, Edwige, Verdezoto, Nervo, Haycraft, Emma, Holdsworth, Michelle

“…Multiple forms of malnutrition coexist in infants and young children (IYC) in Peru. The World Health Organization has proposed double-duty actions (DDAs) to…”
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Antitumoral synergism between a copper(II) complex and cisplatin improves in vitro and in vivo anticancer activity against melanoma, lung and breast cancer cells by Mariani, D., Ghasemishahrestani, Z., Freitas, W., Pezzuto, P., Costa-da-Silva, A.C., Tanuri, A., Kanashiro, M.M., Fernandes, C., Horn, A., Pereira, M.D.

“…Intrinsic resistance of cancer cells is a major concern for the success of chemotherapy, and this undesirable feature stimulates further research into the…”
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cKit⁺ cardiac progenitors of neural crest origin by Hatzistergos, Konstantinos E., Takeuchi, Lauro M., Saur, Dieter, Seidler, Barbara, Dymecki, Susan M., Mai, Jia Jia, White, Ian A., Balkan, Wayne, Kanashiro-Takeuchi, Rosemeire M., Schally, Andrew V., Hare, Joshua M.

“…The degree to whichcKit-expressing progenitors generate cardiomyocytes in the heart is controversial. Genetic fate-mapping studies suggest minimal…”
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Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice by Yuan, Chen-Ching, Priya Muthu, Katarzyna Kazmierczak, Jingsheng Liang, Wenrui Huang, Thomas C. Irving, Rosemeire M. Kanashiro-Takeuchi, Joshua M. Hare, Danuta Szczesna-Cordary

“…Myosin light chain kinase (MLCK)-dependent phosphorylation of the regulatory light chain (RLC) of cardiac myosin is known to play a beneficial role in heart…”
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Diet and food insecurity among mothers, infants, and young children in Peru before and during COVID‐19: A panel survey by Pradeilles, Rebecca, Pareja, Rossina, Creed‐Kanashiro, Hilary M., Griffiths, Paula L., Holdsworth, Michelle, Verdezoto, Nervo, Eymard‐Duvernay, Sabrina, Landais, Edwige, Stanley, Megan, Rousham, Emily K.

“…The COVID‐19 pandemic may impact diet and nutrition through increased household food insecurity, lack of access to health services, and poorer quality diets…”
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Using formative research to design context‐specific animal source food and multiple micronutrient powder interventions to improve the consumption of micronutrients by infants and young children in Tanzania, Kenya, Bangladesh and Pakistan by Robert, Rebecca C., Bartolini, Rosario M., Creed‐Kanashiro, Hilary M., Verney Sward, Allison

“…Optimal complementary feeding practices including consumption of multiple micronutrient powders (MNP) are recommended to improve micronutrient intake by…”
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Hydroxychloroquine Mitigates Dilated Cardiomyopathy Phenotype in Transgenic D94A Mice by Kanashiro-Takeuchi, Rosemeire M, Kazmierczak, Katarzyna, Liang, Jingsheng, Takeuchi, Lauro M, Sitbon, Yoel H, Szczesna-Cordary, Danuta

“…In this study, we aimed to investigate whether short-term and low-dose treatment with hydroxychloroquine (HCQ), an antimalarial drug, can modulate heart…”
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Designing intervention prototypes to improve infant and young child nutrition in Peru: a participatory design study protocol by Rousham, Emily, Pareja, Rossina G, Creed-Kanashiro, Hilary M, Bartolini, Rosario, Pradeilles, Rebecca, Ortega-Roman, Deysi, Holdsworth, Michelle, Griffiths, Paula, Verdezoto, Nervo

“…IntroductionNutrition during the complementary feeding period (6–23 months) is critical to ensure optimal growth and reduce the risk of diet-related disease…”
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Epigenetic variation at the SLC6A4 gene promoter in mother–child pairs with major depressive disorder by Mendonça, M.S., Mangiavacchi, P.M., De Sousa, P.F., Crippa, J.A.S., Mendes, A.V., Loureiro, S.R., Martín-Santos, R., Quirino, C.R., Kanashiro, M.M., Rios, A.F.L.

“…•Genetic and epigenetic analysis in the promoter of the serotonin transporter gene (SLC6A4) in mother–child pairs with depression.•DNA methylation changes…”
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Impacts of selective logging on inbreeding and gene flow in two Amazonian timber species with contrasting ecological and reproductive characteristics by Vinson, C. C., Kanashiro, M., Harris, S. A., Boshier, D. H.

“…Selective logging in Brazil allows for the removal of up to 90% of trees above 50 cm diameter of a given timber species, independent of a species’ life history…”
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Impact of selective logging on inbreeding and gene dispersal in an Amazonian tree population of Carapa guianensis Aubl by CLOUTIER, D, KANASHIRO, M, CIAMPI, A.Y, SCHOEN, D.J

“…Selective logging may impact patterns of genetic diversity within populations of harvested forest tree species by increasing distances separating conspecific…”
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Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells and promote their survival by Florea, Victoria, Majid, Sonia S., Kanashiro-Takeuchi, Rosemeire M., Cai, Ren-Zhi, Block, Norman L., Schally, Andrew V., Hare, Joshua M., Rodrigues, Claudia O.

“…The beneficial effects of agonists of growth hormone-releasing hormone receptor (GHRH-R) in heart failure models are associated with an increase in the number…”
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Pharmacologic and genetic strategies to enhance cell therapy for cardiac regeneration by Kanashiro-Takeuchi, Rosemeire M, Schulman, Ivonne Hernandez, Hare, Joshua M

“…Abstract Cell-based therapy is emerging as an exciting potential therapeutic approach for cardiac regeneration following myocardial infarction (MI). As heart…”
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Effects of selective logging on the mating system and pollen dispersal of Hymenaea courbaril L. (Leguminosae) in the Eastern Brazilian Amazon as revealed by microsatellite analysis by Carneiro, F.S., Lacerda, A.E.B., Lemes, M.R., Gribel, R., Kanashiro, M., Wadt, L.H.O., Sebbenn, A.M.

“…► Mating patterns were investigated in a logged population of Hymenaea courbaril. ► Genetic diversity was reduced and some levels of selfing were observed…”
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Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction by Kanashiro-Takeuchi, Rosemeire M, Tziomalos, Konstantinos, Takeuchi, Lauro M, Treuer, Adriana V, Lamirault, Guillaume, Dulce, Raul, Hurtado, Michael, Song, Yun, Block, Norman L, Rick, Ferenc, Klukovits, Anna, Hu, Qinghua, Varga, Jozsef L, Schally, Andrew V, Hare, Joshua M

“…Whether the growth hormone (GH)/insulin-like growth factor 1(IGF-1) axis exerts cardioprotective effects remains controversial; and the underlying mechanism(s)…”
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Long-term impacts of selective logging on two Amazonian tree species with contrasting ecological and reproductive characteristics: inferences from Eco-gene model simulations by Vinson, C C, Kanashiro, M, Sebbenn, A M, Williams, T C R, Harris, S A, Boshier, D H

“…The impact of logging and subsequent recovery after logging is predicted to vary depending on specific life history traits of the logged species. The Eco-gene…”
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Pigmentation Affects Elastic Fiber Patterning and Biomechanical Behavior of the Murine Aortic Valve by Nasim, Sana, Pandey, Popular, Kanashiro-Takeuchi, Rosemeire M, He, Jin, Hutcheson, Joshua D, Kos, Lidia

“…The aortic valve (AoV) maintains unidirectional blood distribution from the left ventricle of the heart to the aorta for systemic circulation. The AoV leaflets…”
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Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI) by Kanashiro-Takeuchi, Rosemeire M., Takeuchi, Lauro M., Rick, Ferenc G., Dulce, Raul, Treuer, Adriana V., Florea, Victoria, Rodrigues, Claudia O., Paulino, Ellena C., Hatzistergos, Konstantinos E., Selem, Sarah M., Gonzalez, Daniel R., Block, Norman L., Schally, Andrew V., Hare, Joshua M.

“…Both cardiac myocytes and cardiac stem cells (CSCs) express the receptor of growth hormone releasing hormone (GHRH), activation of which improves injury…”
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