Search Results - "Kanaoka, Yuki"

Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages by Koga, Mitsuhisa, Kanaoka, Yuki, Inada, Koshun, Omine, Sai, Kataoka, Yasufumi, Yamauchi, Atsushi

“…Varenicline is a widely used and effective drug for smoking cessation. We have previously reported experimental evidence suggesting that varenicline increases…”
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Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression by Koga, Mitsuhisa, Kanaoka, Yuki, Okamoto, Mana, Nakao, Yuki, Inada, Koshun, Takayama, Saki, Kataoka, Yasufumi, Yamauchi, Atsushi

“…Varenicline is a widely used and effective drug for smoking cessation. We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E…”
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Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase by Koga, Mitsuhisa, Kanaoka, Yuki, Tashiro, Tetsushi, Hashidume, Nagisa, Kataoka, Yasufumi, Yamauchi, Atsushi

“…Smoking cessation is the most effective treatment in patients with emphysema and lung inflammation. The aim of the present study was to examine the effect of…”
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Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor–mitogen activated protein kinase axis by Koga, Mitsuhisa, Kanaoka, Yuki, Sugiyama, Keita, Ohishi, Kaoru, Ejima, Yuka, Hisanaga, Mami, Kataoka, Yasufumi, Yamauchi, Atsushi

“…•Varenicline lowers VE-cadherin expression in human endothelial cells (HUVECs).•Varenicline stimulates migration and MAPK signaling through α7 nAChR in…”
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Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α7 nAChR in macrophages by Kanaoka, Yuki, Koga, Mitsuhisa, Sugiyama, Keita, Ohishi, Kaoru, Kataoka, Yasufumi, Yamauchi, Atsushi

“…Abstract Varenicline is a widely used and effective drug for smoking cessation. It is a partial agonist of the α4β2 nicotinic acetylcholine receptor (nAChR)…”
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Varenicline aggravates plaque formation through alpha 7 nicotinic acetylcholine receptors in ApoE KO mice by Koga, Mitsuhisa, Kanaoka, Yuki, Ohkido, Yuma, Kubo, Naoka, Ohishi, Kaoru, Sugiyama, Keita, Yamauchi, Atsushi, Kataoka, Yasufumi

“…Varenicline is one of the most widely used drugs for smoking cessation. However, whether an adverse effect of varenicline is associated with the risk of…”
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Varenicline aggravates plaque formation through α7 nicotinic acetylcholine receptors in ApoE KO mice by Koga, Mitsuhisa, Kanaoka, Yuki, Ohkido, Yuma, Kubo, Naoka, Ohishi, Kaoru, Sugiyama, Keita, Yamauchi, Atsushi, Kataoka, Yasufumi

“…•Long-term varenicline treatment progressed aortic plaque formation in ApoE KO mice.•Varenicline-aggravated plaque formation was blocked by MLA, an α7 nAChR…”
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Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α 7 nAChR in macrophages by Kanaoka, Yuki, Koga, Mitsuhisa, Sugiyama, Keita, Ohishi, Kaoru, Kataoka, Yasufumi, Yamauchi, Atsushi

“…Varenicline is a widely used and effective drug for smoking cessation. It is a partial agonist of the α β nicotinic acetylcholine receptor (nAChR) and full…”
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BMP4 is increased in the aortas of diabetic ApoE knockout mice and enhances uptake of oxidized low density lipoprotein into peritoneal macrophages by Koga, Mitsuhisa, Yamauchi, Atsushi, Kanaoka, Yuki, Jige, Ryusuke, Tsukamoto, Anna, Teshima, Nao, Nishioku, Tsuyoshi, Kataoka, Yasufumi

“…BMP4, a member of the transforming growth factor-beta superfamily, is upregulated in the aortas of diabetic db/db mice. However, little is known about its role…”
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