Search Results - "Kanai, Yoshiakira"

Gonadal Sex Differentiation and Ovarian Organogenesis along the Cortical–Medullary Axis in Mammals by Imaimatsu, Kenya, Uchida, Aya, Hiramatsu, Ryuji, Kanai, Yoshiakira

“…In most mammals, the sex of the gonads is based on the fate of the supporting cell lineages, which arises from the proliferation of coelomic epithelium (CE)…”
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Comparative anatomy of the hepatobiliary systems in quail and pigeon, with a perspective for the gallbladder-loss by HIGASHIYAMA, Hiroki, KANAI, Yoshiakira

“…Although the gallbladder is one of the characteristic component of the vertebrate body, it has been independently lost in several lineages of mammals and…”
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Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a by Kuroki, Shunsuke, Matoba, Shogo, Akiyoshi, Mika, Matsumura, Yasuko, Miyachi, Hitoshi, Mise, Nathan, Abe, Kuniya, Ogura, Atsuo, Wilhelm, Dagmar, Koopman, Peter, Nozaki, Masami, Kanai, Yoshiakira, Shinkai, Yoichi, Tachibana, Makoto

“…Developmental gene expression is defined through cross-talk between the function of transcription factors and epigenetic status, including histone…”
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Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules by Imura-Kishi, Kasane, Uchida, Aya, Tsunekawa, Naoki, Suzuki, Hitomi, Takase, Hinako M., Hirate, Yoshikazu, Kanai-Azuma, Masami, Hiramatsu, Ryuji, Kurohmaru, Masamichi, Kanai, Yoshiakira

“…In mammalian testes, undifferentiated spermatogonia (A undiff ) undergo differentiation in response to retinoic acid (RA), while their progenitor states are…”
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Single-cell transcriptional analysis reveals developmental stage-dependent changes in retinal progenitors in the murine early optic vesicle by Yamada, Ryuichi, Oguri, Akira, Fujiki, Katsunori, Shirahige, Katsuhiko, Takezoe, Hirotaka, Takahashi, Naoki, Kanai, Yoshiakira

“…The optic vesicle in the developing embryonic eye contains a multitude of neuroepithelial progenitors that subsequently differentiate into functionally…”
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Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis by Kawai, Yasuhiro, Oda, Akihisa, Kanai, Yoshiakira, Goitsuka, Ryo

“…PKnox1 (also known as Prep1) belongs to the TALE family of homeodomain transcription factors that are critical for regulating growth and differentiation during…”
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Sertoli cell replacement in explanted mouse testis tissue supporting host spermatogenesis by Higuchi, Kazusa, Matsumura, Takafumi, Akiyama, Haruhiko, Kanai, Yoshiakira, Ogawa, Takehiko, Sato, Takuya

“…Spermatogenesis takes place in the seminiferous tubules, starting from the spermatogonial stem cell and maturing into sperm through multiple stages of cell…”
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A possible function of Nik-related kinase in the labyrinth layer of delayed delivery mouse placentas by YOMOGITA, Hiroshi, ITO, Hikaru, HASHIMOTO, Kento, KUDO, Akihiko, FUKUSHIMA, Toshiaki, ENDO, Tsutomu, HIRATE, Yoshikazu, AKIMOTO, Yoshihiro, KOMADA, Masayuki, KANAI, Yoshiakira, MIYASAKA, Naoyuki, KANAI-AZUMA, Masami

“…In mice and humans, Nik-related protein kinase (Nrk) is an X-linked gene that encodes a serine/threonine kinase belonging to GCK group 4. Nrk knockout (Nrk KO)…”
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Gene expression and functional abnormalities in XX/Sry Leydig cells by Yanai, Shogo, Baba, Takashi, Inui, Kai, Miyabayashi, Kanako, Han, Soyun, Inoue, Miki, Takahashi, Fumiya, Kanai, Yoshiakira, Ohkawa, Yasuyuki, Choi, Man Ho, Morohashi, Ken-ichirou

“…The SRY gene induces testis development even in XX individuals. However, XX/ Sry testes fail to produce mature sperm, due to the absence of Y chromosome…”
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SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse by Uchida, Aya, Imaimatsu, Kenya, Suzuki, Honoka, Han, Xiao, Ushioda, Hiroki, Uemura, Mami, Imura-Kishi, Kasane, Hiramatsu, Ryuji, Takase, Hinako M., Hirate, Yoshikazu, Ogura, Atsuo, Kanai-Azuma, Masami, Kudo, Akihiko, Kanai, Yoshiakira

“…Seminiferous tubules (STs) in the mammalian testes are connected to the rete testis (RT) via a Sertoli valve (SV). Spermatozoa produced in the STs are released…”
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From Sex Determination to Initial Folliculogenesis in Mammalian Ovaries: Morphogenetic Waves along the Anteroposterior and Dorsoventral Axes by Suzuki, Hitomi, Kanai-Azuma, Masami, Kanai, Yoshiakira

“…Gonadal sex in most mammals is determined based on sex differentiation of the supporting cell lineages. In mouse XY gonads, SRY induces SOX9 upregulation and…”
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Embryonic cholecystitis and defective gallbladder contraction in the Sox17 -haploinsufficient mouse model of biliary atresia by Higashiyama, Hiroki, Ozawa, Aisa, Sumitomo, Hiroyuki, Uemura, Mami, Fujino, Ko, Igarashi, Hitomi, Imaimatsu, Kenya, Tsunekawa, Naoki, Hirate, Yoshikazu, Kurohmaru, Masamichi, Saijoh, Yukio, Kanai-Azuma, Masami, Kanai, Yoshiakira

“…The gallbladder excretes cytotoxic bile acids into the duodenum through the cystic duct and common bile duct system. haploinsufficiency causes biliary…”
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Homeoproteins Six1 and Six4 Regulate Male Sex Determination and Mouse Gonadal Development by Fujimoto, Yuka, Tanaka, Satomi S., Yamaguchi, Yasuka L., Kobayashi, Hiroki, Kuroki, Shunsuke, Tachibana, Makoto, Shinomura, Mai, Kanai, Yoshiakira, Morohashi, Ken-ichirou, Kawakami, Kiyoshi, Nishinakamura, Ryuichi

“…The Y-linked gene Sry regulates mammalian sex determination in bipotential embryonic gonads. Here, we report that the transcription factors Six1 and Six4 are…”
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Cbx2, a Polycomb Group Gene, Is Required for Sry Gene Expression in Mice by Katoh-Fukui, Yuko, Miyabayashi, Kanako, Komatsu, Tomoko, Owaki, Akiko, Baba, Takashi, Shima, Yuichi, Kidokoro, Tomohide, Kanai, Yoshiakira, Schedl, Andreas, Wilhelm, Dagmar, Koopman, Peter, Okuno, Yasushi, Morohashi, Ken-ichirou

“…Mice lacking the function of the polycomb group protein CBX2 (chromobox homolog 2; also known as M33) show defects in gonadal, adrenal, and splenic…”
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Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation by Hirate, Yoshikazu, Suzuki, Hitomi, Kawasumi, Miyuri, Takase, Hinako M., Igarashi, Hitomi, Naquet, Philippe, Kanai, Yoshiakira, Kanai-Azuma, Masami

“…Embryonic implantation comprises a dynamic and complicated series of events, which takes place only when the maternal uterine endometrium is in a receptive…”
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SOX9 Regulates Prostaglandin D Synthase Gene Transcription in Vivo to Ensure Testis Development by Wilhelm, Dagmar, Hiramatsu, Ryuji, Mizusaki, Hirofumi, Widjaja, Laura, Combes, Alexander N., Kanai, Yoshiakira, Koopman, Peter

“…In mammals, male sex is determined by the Y-chromosomal gene Sry (sex-determining region of Y chromosome). The expression of Sry and subsequently Sox9 (SRY box…”
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A critical time window of Sry action in gonadal sex determination in mice by Ryuji Hiramatsu, Shogo Matoba, Masami Kanai-Azuma, Naoki Tsunekawa, Yuko Katoh-Fukui, Masamichi Kurohmaru, Ken-ichirou Morohashi, Dagmar Wilhelm, Peter Koopman, Yoshiakira Kanai

“…In mammals, the Y-linked sex-determining gene Sry cell-autonomously promotes Sertoli cell differentiation from bipotential supporting cell precursors through…”
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DNMT1 Expression and DNA Methylation in Intraductal Papillary Neoplasms of the Bile Duct by Doi, Reiko, Fukumura, Yuki, Lu, Rong, Hirabayashi, Kenichi, Kinowaki, Yuko, Nakanuma, Yasuni, Kanai, Yoshiakira, Nakahodo, Jun, Sasahara, Noriko, Saito, Tsuyoshi, Yao, Takashi

“…Intraductal papillary neoplasms of the bile duct (IPNB) are histologically and clinically classified as type 1 and 2. This study aimed to identify the…”
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Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder by Higashiyama, Hiroki, Uemura, Mami, Igarashi, Hitomi, Kurohmaru, Masamichi, Kanai‐Azuma, Masami, Kanai, Yoshiakira

“…The gallbladder is the hepatobiliary organ for storing and secreting bile fluid, and is a synapomorphy of extant vertebrates. However, this organ has been…”
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Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice by Saba, Rie, Kitajima, Keiko, Rainbow, Lucille, Engert, Silvia, Uemura, Mami, Ishida, Hidekazu, Kokkinopoulos, Ioannis, Shintani, Yasunori, Miyagawa, Shigeru, Kanai, Yoshiakira, Kanai-Azuma, Masami, Koopman, Peter, Meno, Chikara, Kenny, John, Lickert, Heiko, Saga, Yumiko, Suzuki, Ken, Sawa, Yoshiki, Yashiro, Kenta

“…The endocardium is the endothelial component of the vertebrate heart and plays a key role in heart development. Where, when, and how the endocardium segregates…”
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