Search Results - "Kanai, Yasukazu"

Development of an ultrahigh resolution Si-PM based PET system for small animals by Yamamoto, Seiichi, Watabe, Hiroshi, Kanai, Yasukazu, Watabe, Tadashi, Kato, Katsuhiko, Hatazawa, Jun

“…Since a high resolution PET system is needed for small animal imaging, especially for mouse studies, we developed a new small animal PET system that decreased…”
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First measured optical image of Cerenkov-light in water during irradiation of neutron beam from boron neutron capture therapy (BNCT) system by Yabe, Takuya, Yamamoto, Seiichi, Hu, Naonori, Kanai, Yasukazu, Tanaka, Hiroki, Ono, Koji

“…Optical imaging that detects Cerenkov-light or the luminescence of water is a promising method to measure dose distributions in radiotherapy due to its ability…”
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Development of ultrahigh resolution Si-PM-based PET system using 0.32 mm pixel scintillators by Yamamoto, Seiichi, Watabe, Hiroshi, Watabe, Tadashi, Ikeda, Hayato, Kanai, Yasukazu, Ogata, Yoshimune, Kato, Katsuhiko, Hatazawa, Jun

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Evaluation of the total distribution volume of 18F-FBPA in normal tissues of healthy volunteers by non-compartmental kinetic modeling by Romanov, Victor, Isohashi, Kayako, Alobthani, Galal, Beshr, Rouaa, Horitsugi, Genki, Kanai, Yasukazu, Naka, Sadahiro, Watabe, Tadashi, Shimosegawa, Eku, Hatazawa, Jun

“…Objective Boron neutron capture therapy (BNCT) is a noninvasive radiation therapy method for cancer treatment. In BNCT, 4-borono-2-[ 18…”
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Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2 by Aoki, Masanao, Watabe, Tadashi, Nagamori, Shushi, Naka, Sadahiro, Ikeda, Hayato, Kongpracha, Pornparn, Horitsugi, Genki, Kanai, Yasukazu, Shimosegawa, Eku, Kanai, Yoshikatsu, Hatazawa, Jun

“…Objective L-type amino acid transporter 1 (LAT1) is strongly expressed on the cell membrane in various types of human cancer cells, while being minimally…”
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Preliminary outcomes of boron neutron capture therapy for head and neck cancers as a treatment covered by public health insurance system in Japan: Real‐world experiences over a 2‐year period by Takeno, Satoshi, Yoshino, Yuki, Aihara, Teruhito, Higashino, Masaaki, Kanai, Yasukazu, Hu, Naonori, Kakino, Ryo, Kawata, Ryo, Nihei, Keiji, Ono, Koji

“…Purpose Since June 2020, boron neutron capture therapy (BNCT) has been a health care service covered by health insurance in Japan to treat locally advanced or…”
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Design and performance from an integrated PET/MRI system for small animals by Yamamoto, Seiichi, Imaizumi, Masao, Kanai, Yasukazu, Tatsumi, Mitsuaki, Aoki, Masaaki, Sugiyama, Eiji, Kawakami, Makoto, Shimosegawa, Eku, Hatazawa, Jun

“…Objective Although simultaneous measurements of PET and magnetic resonance imaging (MRI) can provide interesting results in molecular imaging research, most of…”
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Improved Stability and Practicality for Synthesis of 4-Borono-2-[18F]fluoro-l-phenylalanine by Combination of [18O]O2 Single-Use and [18F]CH3COOF Labeling Agents by Naka, Sadahiro, Watanabe, Toshimitsu, Kanai, Yasukazu, Watabe, Tadashi, Tatsumi, Mitsuaki, Kato, Hiroki, Shimosegawa, Eku, Hatazawa, Jun

“…Purpose 4-Borono-2-[ 18 F]fluoro- l -phenylalanine ([ 18 F]FBPA) synthesized with [ 18 F]F 2 , produced using the 18 O(p, n) 18 F reaction, has been reported…”
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Synthesis and evaluation of [18F]FBNAF, a STAT3-targeting probe, for PET imaging of tumor microenvironment by Miyazaki, Anna, Kanai, Yasukazu, Wakamori, Keita, Mizuguchi, Serina, Futatsugi, Mikiya, Hirano, Fuko, Kondo, Naoya, Temma, Takashi

“…Background Signal transducer and activator of transcription 3 (STAT3) is a protein that regulates cell proliferation and differentiation, and it is attracting…”
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Development of PET Imaging to Visualize Activated Macrophages Accumulated in the Transplanted iPSc-Derived Cardiac Myocytes of Allogeneic Origin for Detecting the Immune Rejection of Allogeneic Cell Transplants in Mice by Kashiyama, Noriyuki, Miyagawa, Shigeru, Fukushima, Satsuki, Kawamura, Takuji, Kawamura, Ai, Yoshida, Shohei, Harada, Akima, Watabe, Tadashi, Kanai, Yasukazu, Toda, Koichi, Hatazawa, Jun, Sawa, Yoshiki

“…Allogeneic transplantation (Tx) of induced pluripotent stem cells (iPSCs) is a promising tissue regeneration therapy. However, this inevitably induces…”
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Development of an ultrahigh-resolution Si-PM-based dual-head GAGG coincidence imaging system by Yamamoto, Seiichi, Watabe, Hiroshi, Kanai, Yasukazu, Kato, Katsuhiko, Hatazawa, Jun

“…A silicon photomultiplier (Si-PM) is a promising photodetector for high resolution PET systems due to its small channel size and high gain. Using Si-PMs, it…”
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Application of astatine-210: Evaluation of astatine distribution and effect of pre-injected iodide in whole body of normal rats by Ikeda, Hayato, Hayashi, Yoshihiko, Takahashi, Naruto, Watabe, Tadashi, Kanai, Yasukazu, Shinohara, Atsushi, Kato, Hiroki, Watabe, Hiroshi, Shimosegawa, Eku, Hatazawa, Jun

“…We proposed use of astatine-210 in preclinical study. Astatine-210 has higher yield of production and is easier to quantify than astatine-211. We produced…”
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Development of a PET/OMRI combined system for simultaneous imaging of positron and free radical probes for small animals by Yamamoto, Seiichi, Watabe, Tadashi, Ikeda, Hayato, Kanai, Yasukazu, Ichikawa, Kazuhiro, Nakao, Motonao, Kato, Katsuhiko, Hatazawa, Jun

“…Purpose: Positron emission tomography (PET) has high sensitivity for imaging radioactive tracer distributions in subjects. However, it is not possible to image…”
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Development of a prototype Open-close positron emission tomography system by Yamamoto, Seiichi, Okumura, Satoshi, Watabe, Tadashi, Ikeda, Hayato, Kanai, Yasukazu, Toshito, Toshiyuki, Komori, Masataka, Ogata, Yoshimune, Kato, Katsuhiko, Hatazawa, Jun

“…We developed a prototype positron emission tomography (PET) system based on a new concept called Open-close PET, which has two modes: open and close-modes. In…”
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Selective accumulation of [62Zn]-labeled glycoconjugated porphyrins as multi-functional positron emission tomography tracers in cancer cells by Tamura, Masato, Matsui, Hirofumi, Hirohara, Shiho, Kakiuchi, Kiyomi, Tanihara, Masao, Takahashi, Naruto, Nakai, Kozi, Kanai, Yasukazu, Watabe, Hiroshi, Hatazawa, Jun

“…Positron-emission tomography (PET) can be used to visualize active stage cancer. Fluorine-18 ([18F])-labeled 2-([18F])2-deoxy-2-fluoroglucose (([18F])-FDG),…”
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Development of a p38α-selective radioactive probe for qualitative diagnosis of cancer using SPECT by Hirata, Masahiko, Yao, Tatsuma, Fujimura, Shigeaki, Kanai, Yasukazu, Yoshimoto, Mitsuyoshi, Sato, Takaji, Ohmomo, Yoshiro, Temma, Takashi

“…Objective p38 mitogen-activated protein (MAP) kinase (p38α) has drawn attention as a new target molecule for the treatment and diagnosis of cancer, and its…”
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Practical calculation method to estimate the absolute boron concentration in tissues using 18F-FBPA PET by Watabe, Tadashi, Hanaoka, Kohei, Naka, Sadahiro, Kanai, Yasukazu, Ikeda, Hayato, Aoki, Masanao, Shimosegawa, Eku, Kirihata, Mitsunori, Hatazawa, Jun

“…Purpose The purpose of this study was to establish a practical method to estimate the absolute boron concentrations in the tissues based on the standardized…”
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Development of a PET/Cerenkov‐light hybrid imaging system by Yamamoto, Seiichi, Hamamura, Fuka, Watabe, Tadashi, Ikeda, Hayato, Kanai, Yasukazu, Watabe, Hiroshi, Kato, Katsuhiko, Ogata, Yoshimune, Hatazawa, Jun

“…Purpose: Cerenkov‐light imaging is a new molecular imaging technology that detects visible photons from high‐speed electrons using a high sensitivity optical…”
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Exploration of the threshold SUV for diagnosis of malignancy using 18F-FBPA PET/CT by Isohashi, Kayako, Kanai, Yasukazu, Aihara, Teruhito, Hu, Naonori, Fukushima, Kentaro, Baba, Ichiro, Hirokawa, Fumitoshi, Kakino, Ryo, Komori, Tsuyoshi, Nihei, Keiji, Hatazawa, Jun, Ono, Koji

“…Background The goal of the study was to evaluate the diagnostic ability of 18 F-FBPA PET/CT for malignant tumors. Findings from 18 F-FBPA and 18 F-FDG PET/CT…”
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Evaluation of the default-mode network by quantitative 15O-PET: comparative study between cerebral blood flow and oxygen consumption by Aoe, Jo, Watabe, Tadashi, Shimosegawa, Eku, Kato, Hiroki, Kanai, Yasukazu, Naka, Sadahiro, Matsunaga, Keiko, Isohashi, Kayako, Tatsumi, Mitsuaki, Hatazawa, Jun

“…Objective Resting-state functional MRI (rs-fMRI) has revealed the existence of a default-mode network (DMN) based on spontaneous oscillations of the blood…”
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