Search Results - "Kanai, Genta"

Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients by Ohashi, Yuki, Toyoda, Masao, Saito, Nobumichi, Koizumi, Masahiro, Kanai, Genta, Komaba, Hirotaka, Kimura, Moritsugu, Wada, Takehiko, Takahashi, Hiroo, Takahashi, Yuichiro, Ishida, Naoto, Kakuta, Takatoshi, Fukagawa, Masafumi, Ichida, Kimiyoshi

“…Two-thirds of urate is excreted via the renal pathway and the remaining one-third via the extra-renal pathway, the latter mainly via the intestine in healthy…”
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Effect of Sevelamer and Calcium-Based Phosphate Binders on Coronary Artery Calcification and Accumulation of Circulating Advanced Glycation End Products in Hemodialysis Patients by Kakuta, Takatoshi, MD, PhD, Tanaka, Reika, MD, PhD, Hyodo, Toru, MD, PhD, Suzuki, Hajime, MD, PhD, Kanai, Genta, MD, PhD, Nagaoka, Mikako, MD, PhD, Takahashi, Hiroo, MD, PhD, Hirawa, Nobuhito, MD, PhD, Oogushi, Yoichi, PhD, Miyata, Toshio, MD, PhD, Kobayashi, Hiroyuki, MD, DMSc, MSCI, Fukagawa, Masafumi, MD, PhD, Saito, Akira, MD, PhD

“…Background Some trials have indicated that coronary artery calcification progresses more slowly in sevelamer-treated dialysis patients than in those using…”
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Parathyroid hormone-producing cells exist in adipose tissues surrounding the parathyroid glands in hemodialysis patients with secondary hyperparathyroidism by Kakuta, Takatoshi, Sawada, Kaichiro, Kanai, Genta, Tatsumi, Ryoko, Miyakogawa, Takayo, Ishida, Mari, Nakazawa, Raima, Fukagawa, Masafumi

“…Possible ectopic parathyroid hormone (PTH) production in adipose tissues surrounding hyperplastic parathyroid glands was examined in patients with secondary…”
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Changes in Fibroblast Growth Factor 23 and Soluble Klotho Levels After Hemodialysis Initiation by Kawabata, Chiaki, Komaba, Hirotaka, Ishida, Hiroaki, Nakagawa, Yosuke, Hamano, Naoto, Koizumi, Masahiro, Kanai, Genta, Wada, Takehiko, Nakamura, Michio, Fukagawa, Masafumi

“…Patients with chronic kidney failure have markedly elevated fibroblast growth factor 23 (FGF-23) levels and decreased soluble Klotho levels. However, no…”
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Feasibility of photodynamic therapy for secondary hyperparathyroidism in chronic renal failure rats by Miyakogawa, Takayo, Kanai, Genta, Tatsumi, Ryoko, Takahashi, Hiroo, Sawada, Kaichiro, Kakuta, Takatoshi, Fukagawa, Masafumi

“…Background Feasibility of photodynamic therapy (PDT) for secondary hyperparathyroidism (SHPT) was examined in a rat model of SHPT. Methods A photosensitizer,…”
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Small-cell Carcinoma of the Endometrium Presenting as Cushing’s Syndrome by SATO, Haruhiro, KANAI, Genta, KAJIWARA, Hiroshi, ITOH, Johbu, OSAMURA, Robert Yoshiyuki

“…Small-cell carcinoma (SCC) of neuroendocrine type is an uncommon tumor of the endometrium. No previous report has documented Cushing’s syndrome due to ectopic…”
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Bone mineral metabolism that kidney controls by Kanai, Genta, Fukagawa, Masafumi

“…With progressive loss of kidney function, patients with chronic kidney disease develop multiple mineral metabolism abnormalities. Chronic kidney…”
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Evaluation of bioartificial renal tubule device prepared with human renal proximal tubular epithelial cells cultured in serum-free medium by Takahashi, Hiroo, Sawada, Kaichiro, Kakuta, Takatoshi, Suga, Takao, Hanai, Kazuya, Kanai, Genta, Fujimura, Satoshi, Sanechika, Noriyuki, Terachi, Toshiro, Fukagawa, Masafumi, Saito, Akira

“…Bioartificial renal tubule devices (BTD) use cell therapy to improve conditions commonly observed in recipients of artificial kidneys for treatment of kidney…”
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CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). Gene therapy for secondary hyperparathyroidism by Kanai, Genta, Fukagawa, Masafumi

“…Secondary hyperparathyroidism (SHPT) is one of the most important complications of chronic kidney disease. Although 1,25-D pulse therapy is effective for SHPT,…”
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Can Cinacalcet Replace Parathyroid Intervention in Severe Secondary Hyperparathyroidism? by Kakuta, Takatoshi, Tanaka, Reika, Kanai, Genta, Sawaya, Asako, Hirukawa, Takashi, Sato, Atsuhiro, Saito, Akira

“…A 6‐month observational study was conducted in 61 patients (33 men and 28 women, mean age 54.8 ± 12.4 years) treated with cinacalcet in whom parathyroid…”
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Enhancement of permeability in endothelial cells for the development of an antithrombogenic bioartificial hemofilter by Vu, Duc M, Yokoyama, Tun A, Sawada, Kaichiro, Inagaki, Miho, Kanai, Genta, Lu, Jianxin, Kakuta, Takatoshi, Adler, Stephen, Nangaku, Masaomi, Saito, Akira

“…For the development of an antithrombogenic bioartificial hemofilter, in which the inner surface of hollow fibers is lined by endothelial cells, it is essential…”
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Prevention of LLC-PK1 cell overgrowth in a bioartificial renal tubule device using a MEK inhibitor, U0126 by INAGAKI, Miho, YOKOYAMA, Tun A, SAWADA, Kaichiro, DUC, Vu M, KANAI, Genta, JIANXIN LU, KAKUTA, Takatoshi, SAITO, Akira

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Atrial Fibrillation Induced by Post-Parathyroidectomy Transient Thyrotoxicosis by Sato, Haruhiro, Miyamoto, Yoshiyasu, Inagaki, Miho, Kanai, Genta, Suzuki, Hajime, Tanaka, Reika, Kakuta, Takatoshi, Saito, Akira

“…We describe a 59-year-old Japanese woman with post-parathyroidectomy transient thyrotoxicosis and atrial fibrillation. She underwent parathyroidectomy for…”
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Taste Disorder As A Common Cause Of Enhanced Salt Intake In Dialysis Patients by Okamoto, Mariko, Osaki, Toshiko, Aoki, Daisuke, Fujii, Honami, Ishii, Hiroaki, Kanai, Genta, Fukagawa, Masafumi

“…Salt intake is a key, but hard-to achieve target of nutrition guidance in chronic hemodialysis (HD) patients. In this study, we examined the influence of…”
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Present status and perspectives of bioartificial kidneys by Saito, Akira, Aung, Tun, Sekiguchi, Koji, Sato, Yoshinobu, Vu, Duc M, Inagaki, Miho, Kanai, Genta, Tanaka, Reika, Suzuki, Hajime, Kakuta, Takatoshi

“…Currently, hemodialysis is not adequate as a renal replacement therapy because it provides intermittent treatment and does not provide the metabolic function…”
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Relationship Between the Weight of Parathyroid Glands and Their Secretion of Parathyroid Hormone in Hemodialysis Patients With Secondary Hyperparathyroidism by Kakuta, Takatoshi, Tanaka, Reika, Kanai, Genta, Miyamoto, Yoshiyasu, Inagaki, Miho, Suzuki, Hajime, Fukagawa, Masafumi, Saito, Akira

“…Secondary hyperparathyroidism is one of the common and important abnormalities of mineral metabolism in hemodialysis patients. In this study we investigated…”
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Impact of Parathyroidectomy on Serum FGF23 and Soluble Klotho in Hemodialysis Patients With Severe Secondary Hyperparathyroidism by Takahashi, Hiroo, Komaba, Hirotaka, Takahashi, Yuichiro, Sawada, Kaichiro, Tatsumi, Ryoko, Kanai, Genta, Suzuki, Hajime, Kakuta, Takatoshi, Fukagawa, Masafumi

“…Context: Klotho is a transmembrane protein that functions as a coreceptor for fibroblast growth factor 23 (FGF23). Klotho is cleaved and released into the…”
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SP640CALCIMIMETICS AND VITAMIN D ANALOGUES INDUCE APOPTOSIS IN CULTURED PARATHYROID PSEUDOGLANDS by Kanai, Genta, Sawada, Kaichiro, Kakuta, Takatoshi, Fukagawa, Masafumi

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Vitamin D receptor agonist VS-105 directly modulates parathyroid hormone expression in human parathyroid cells and in 5/6 nephrectomized rats by Sawada, Kaichiro, Wu-Wong, J. Ruth, Chen, Yung-wu, Wessale, Jerry L., Kanai, Genta, Kakuta, Takatoshi, Fukagawa, Masafumi

“…•VS-105 effectively down-regulates PTH mRNA expression in human parathyroid cells.•VS-105 reduces secreted PTH in human parathyroid cells.•VS-105 also…”
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Cinacalcet induces apoptosis in parathyroid cells in patients with secondary hyperparathyroidism: histological and cytological analyses by Tatsumi, Ryoko, Komaba, Hirotaka, Kanai, Genta, Miyakogawa, Takayo, Sawada, Kaichiro, Kakuta, Takatoshi, Fukagawa, Masafumi

“…Previous studies reported a reduction in parathyroid gland volume during treatment with cinacalcet in patients with secondary hyperparathyroidism (SHPT)…”
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