Search Results - "Kanada, A."
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Immune responses to model antigen elicited by immunization via conjunctiva associated lymphoid tissue
Published in Acta ophthalmologica (Oxford, England) (01-09-2012)“…Purpose There is an excessive demand to develop vaccines against many of the pathogens that infect mucosal tissues or have a mucosal port of entry. Parenteral…”
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Cytometric analysis of lidocaine-induced cytotoxicity: A model experiment using rat thymocytes
Published in Toxicology (Amsterdam) (20-01-2006)“…Lidocaine is a local anesthetic possessing both lipophilic and hydrophilic properties. It also acts as a surfactant. Thus, the disruption of membranes,…”
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Mediators of nonadrenergic, noncholinergic inhibition in the proximal, middle and distal regions of rat colon
Published in British journal of pharmacology (01-02-1993)“…1 The mediators of non‐adrenergic non‐cholinergic (NANC) relaxation of the longitudinal muscle of rat proximal, middle and distal colon were examined in vitro…”
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1180PD - Active immunization with immune checkpoint inhibitors-mimotope elicits strong anti-tumour effect against HER-2/neu-expressing tumours
Published in Annals of oncology (01-10-2019)“…Application of monoclonal antibodies (mAbs) as immune checkpoint inhibitors (ICIs) has demonstrated remarkable activity in cancer immunotherapy. Active…”
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1180PDActive immunization with immune checkpoint inhibitors-mimotope elicits strong anti-tumour effect against HER-2/neu-expressing tumours
Published in Annals of oncology (01-10-2019)“…Abstract Background Application of monoclonal antibodies (mAbs) as immune checkpoint inhibitors (ICIs) has demonstrated remarkable activity in cancer…”
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Active immunization with immune checkpoint inhibitors-mimotope elicits strong anti-tumour effect against HER-2/neu-expressing tumours
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Prostate selectivity of JTH‐601‐G1, an active metabolite of JTH‐601, in dogs
Published in BJU international (01-03-2000)“…Objective To evaluate the effect of JTH‐601‐G1, an active metabolite and glucuronide conjugate of JTH‐601 (an α1‐adrenoceptor antagonist), on smooth muscle…”
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A New Strategy Toward B Cell-Based Cancer Vaccines by Active Immunization With Mimotopes of Immune Checkpoint Inhibitors
Published in Frontiers in immunology (27-05-2020)“…Therapeutic monoclonal antibodies (mAbs), targeting tumor antigens, or immune checkpoints, have demonstrated a remarkable anti-tumor effect against various…”
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Escherichia coli Nissle 1917 bacterial ghosts retain crucial surface properties and express chlamydial antigen: an imaging study of a delivery system for the ocular surface
Published in Drug design, development and therapy (01-01-2015)“…To target chronic inflammatory ocular surface diseases, a drug delivery platform is needed that is safe, possesses immunomodulatory properties, and can be used…”
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Angina-like syndrome with diazoxide therapy for hypertensive crisis
Published in Annals of internal medicine (01-06-1976)“…In 14 patients with hypertensive crisis treated with diazoxide, close monitoring of blood pressure, heart rate, and symptoms was performed. Standard 12-lead…”
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Polysorbate 80 increases the susceptibility to oxidative stress in rat thymocytes
Published in Toxicology (Amsterdam) (01-02-2005)“…Effect of simultaneous application of polysorbate 80, a nonionic surfactant widely used in pharmaceutical products, and hydrogen peroxide on rat thymocytes was…”
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Cremophor EL, a non-ionic surfactant, promotes Ca2+-dependent process of cell death in rat thymocytes
Published in Toxicology (Amsterdam) (01-08-2005)Get full text
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Effect of JTH-601, a novel alpha(1)-adrenoceptor antagonist, on prostate function in dogs
Published in European journal of pharmacology (07-04-2000)“…We examined the effect of JTH-601 (3-¿N-[2-(4-hydroxy-2-isopropyl-5-methylphenoxy)ethyl]-N-methylaminom ethyl¿-4-methoxy-2,5,6-trimethylphenol hemifumarate), a…”
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Cremophor EL, a non-ionic surfactant, promotes Ca super(2+)-dependent process of cell death in rat thymocytes
Published in Toxicology (Amsterdam) (01-08-2005)“…Cremophor EL, a surfactant for pharmaceutical products, augments the cytotoxicity of hydrogen peroxide in rat thymocytes [Iwase, K. Oyama, Y. Tatsuishi, T…”
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Aspirin hepatotoxicity
Published in American journal of hospital pharmacy (01-03-1978)“…A case of aspirin hepatotoxicity in a 46-year-old male with rheumatoid arthritis is discussed, and this adverse reaction is reviewed. The patient was started…”
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Cremophor EL augments the cytotoxicity of hydrogen peroxide in lymphocytes dissociated from rat thymus glands
Published in Toxicology letters (01-12-2004)“…The pharmaceutical uses of cremophor EL, a non-ionic surfactant, are similar to those of polysorbate 80. In our previous study, polysorbate 80 exerted some…”
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Extract of Ginkgo biloba Leaves Attenuates Kainate-Induced Increase in Intracellular Ca2+ Concentration of Rat Cerebellar Granule Neurons
Published in Biological & Pharmaceutical Bulletin (01-05-2005)“…In order to reveal one of possible mechanisms for neuronal protective action of extract of Ginkgo biloba leaves (EGBL), the effect of EGBL on kainate- and…”
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Dissociation of cyclic GMP level and nitric oxide-induced inhibitory responses in rat colon
Published in Japanese journal of pharmacology (1992)Get full text
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