Search Results - "Kan, H.E"

Quantitative MRI and strength measurements in the assessment of muscle quality in Duchenne muscular dystrophy by Wokke, B.H, van den Bergen, J.C, Versluis, M.J, Niks, E.H, Milles, J, Webb, A.G, van Zwet, E.W, Aartsma-Rus, A, Verschuuren, J.J, Kan, H.E

“…Abstract The purpose of this study was to assess leg muscle quality and give a detailed description of leg muscle involvement in a series of Duchenne muscular…”
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Non-uniform muscle fat replacement along the proximodistal axis in Duchenne muscular dystrophy by Hooijmans, M.T, Niks, E.H, Burakiewicz, J, Anastasopoulos, C, van den Berg, S.I, van Zwet, E, Webb, A.G, Verschuuren, J.J.G.M, Kan, H.E

“…Highlights • Muscle fat replacement is non-uniformly distributed along the proximodistal axis in DMD. • Fat fractions are higher in the distal and proximal…”
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G.P.124 by Wokke, B.H, van den Bergen, J.C, Hooijmans, M.H, Verschuuren, J.J, Niks, E.H, Kan, H.E

“…Exon-skipping drugs in Duchenne muscular dystrophy (DMD) aim to ameliorate the phenotype by restoring truncated dystrophin expression. This potentially leads…”
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G.O.11 by Hooijmans, M.T, Wokke, B.H.A, Goemans, N, Campion, G, Verschuuren, J.J.G, Niks, E.H, Kan, H.E

“…Exon skipping in Duchenne muscular dystrophy (DMD) aims to restore dystrophin expression and maintain muscle function. The largest RCT so far targeting exon 51…”
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G.P.4 by Wokke, B.H, van den Bergen, J.C, Reijnierse, M, Rijswijk, C.S, Kan, H.E, Verschuuren, J.J

“…Becker muscular dystrophy (BMD) presents with limb-girdle distribution of muscle weakness similar to limb girdle muscular dystrophies (LGMDs). To facilitate…”
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Proton magnetic resonance spectroscopy indicates preserved cerebral biochemical composition in Duchenne muscular dystrophy patients by Niks, E.H, Doorenweerd, N, Hooijmans, M.T, Schubert, S.A, Webb, A.G, Straathof, C.S.M, van Zwet, E.W, van Buchem, M.A, Verschuuren, J.J.G.M, Hendriksen, J.G.M, Kan, H.E

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P.13.7 Elevated muscle metabolites in Becker muscular dystrophy detected by MR spectroscopy by Hooijmans, M.T, Wokke, B.H.A, van den Bergen, J.C, Aartsma-Rus, A.A, Niks, E.H, Webb, A.G, Verschuuren, J.J.G, Kan, H.E

“…Becker muscular dystrophy (BMD) is characterized by progressive muscle weakness and a variable disease course. Different muscles become infiltrated with fat at…”
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G.P.126 by Doorenweerd, N, Straathof, C.S.M, Dumas, E.M, Spitali, P, Ginjaar, H.B, Wokke, B.H, Schrans, D.G.M, van den Bergen, J.C, van Zwet, E.W, Webb, A, van Buchem, M.A, Verschuuren, J.J.G, Hendriksen, J.G.M, Niks, E.H, Kan, H.E

“…A genotype-phenotype correlation has been suggested for cognitive and behavioral problems associated with Duchenne muscular dystrophy (DMD). We have previously…”
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G.P.127 by Doorenweerd, N, Dumas, E.M, Ghariq, E, Schmid, S, Straathof, C.S.M, Spitali, P, Ginjaar, H.B, Wokke, B.H, Schrans, D.G.M, van den Bergen, J.C, van Zwet, E.W, Webb, A, van Buchem, M.A, van Osch, M.J.P, Verschuuren, J.J.G, Hendriksen, J.G.M, Niks, E.H, Kan, H.E

“…Duchenne muscular dystrophy (DMD) is a neuromuscular disorder known to be associated with specific learning and behavioral disabilities. Recently, we found…”
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D.P.15 Quantitative T2 relaxation times in lower leg of Duchenne and Becker muscular dystrophy patients by Wokke, B.H, Van den Bergen, J.C, Verschuuren, J.J, Kan, H.E

“…Abstract Edema can be present in muscles of Duchenne muscular dystrophy (DMD) patients, and is thought to indicate inflammation. It can be quantified using MRI…”
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P.2.12 The Duchenne brain: A matter of grey and white by Doorenweerd, N, Straathof, C.S.M, Dumas, E.M, Niks, E.H, Schrans, D.G.M, Wokke, B.H.A, van den Bergen, J.C, Webb, A.G, van Buchem, M.A, Hendriksen, J.G.M, Verschuuren, J.J.G, Kan, H.E

“…Learning and behavioral problems are common in Duchenne muscular dystrophy (DMD) patients. In normal brain, various dystrophin isoforms are expressed, but…”
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PP09.4 – 2839: Reduced cerebral blood flow in Duchenne muscular dystrophy and related to the Dp140 isoform by Niks, E.H, Doorenweerd, N, Dumas, E.M, Ghariq, E, Schmid, S, Straathof, C.S.M, Spitali, P, Ginjaar, H.B, Wokke, B.H.A, Schrans, D.G.M, van den Bergen, J.C, van Zwet, E.W, Webb, A.G, van Buchem, M.A, Roest, A.A.W, van Osch, M.J.P, Verschuuren, J.J.G.M, Hendriksen, J.G.M, Kan, H.E

“…Objective Duchenne muscular dystrophy (DMD) is associated with specific learning and behavioral disabilities. Mutations in the DMD gene lead to absence of…”
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G.P.83 Temporal muscle hypertrophy and skull morphology in DMD patients by Straathof, C.S.M, Doorenweerd, N, Wokke, B.H.A, Dumas, E.M, Webb, A.G, Buchem, M.A, Niks, E.H, Verschuuren, J.J.G, Kan, H.E

“…Abstract Hypertrophy is an adaptive response of muscle. This is a well-known phenomenon of the calve muscles in Duchenne muscular dystrophy (DMD), but less…”
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P4.21 MR imaging and spectroscopy of the brain in DMD by Straathof, C.S.M, Wokke, B.H.A, Middelkoop, H.A.M, van Buchem, M.A, Webb, A.G, Verschuuren, J.J.G, Kan, H.E

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Evaluation of skeletal muscle DTI in patients with duchenne muscular dystrophy by Hooijmans, M. T., Damon, B. M., Froeling, M., Versluis, M. J., Burakiewicz, J., Verschuuren, J. J. G. M., Niks, E. H., Webb, A. G., Kan, H. E.

“…Diffusion tensor imaging (DTI) is a popular method to assess differences in fiber organization in diseased and healthy muscle tissue. Previous work has shown…”
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Elevated phosphodiester and T 2 levels can be measured in the absence of fat infiltration in Duchenne muscular dystrophy patients by Hooijmans, M T, Niks, E H, Burakiewicz, J, Verschuuren, J J G M, Webb, A G, Kan, H E

“…Quantitative MRI and MRS are increasingly important as non-invasive outcome measures in therapy development for Duchenne muscular dystrophy (DMD). Many studies…”
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Elevated phosphodiester and T2 levels can be measured in the absence of fat infiltration in Duchenne muscular dystrophy patients by Hooijmans, M.T., Niks, E.H., Burakiewicz, J., Verschuuren, J.J.G.M., Webb, A.G., Kan, H.E.

“…Quantitative MRI and MRS are increasingly important as non‐invasive outcome measures in therapy development for Duchenne muscular dystrophy (DMD). Many studies…”
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D14 - Brain imaging indicates genotype-phenotype association in Duchenne muscular dystrophy by Doorenweerd, N., Bettolo, C.M., Hollingsworth, K.G., Hendriksen, J.G.M., Niks, E.H., Straub, V., Kan, H.E.

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Brain imaging indicates genotype-phenotype association in Duchenne muscular dystrophy by Doorenweerd, N., Bettolo, C.M., Hollingsworth, K.G., Hendriksen, J.G.M., Niks, E.H., Straub, V., Kan, H.E.

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The Effect Of Mirabegron On Energy Expenditure, Brown Adipose Tissue And The Lipidomic Profile In Healthy Lean South Asian And White Caucasian Men by Martinez-Tellez, B., Nahon, K.J., Janssen, L.G.M., Sardjoe-Mishre, A.S., van Weeghel, M., Vaz, F.M., Houtkooper, R., Burakiewicz, J., Dzyubachyk, O., Kooijman, S., Webb, A.G., Kan, H.E., Berbée, J.F.P., Jazet, I.M., Boon, M., Rensen, P.C.N.

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