Search Results - "Kan, Amanda"

Kaposiform haemangioendothelioma of the spine associated with fixed hyperlordotic deformity and Kasabach–Merritt Syndrome: a case report and literature review by Chin, Leanne H. Q., Fung, Kevin K. F., Chan, Joyce P. K., Kan, Amanda N. C., Yuen, M. K.

“…Kaposiform haemangioendothelioma (KHE) is a rare childhood disease classified by the International Society for the Study of Vascular Anomalies (ISSVA) as a…”
Get full text

Durable disease control with apatinib, irinotecan and temozolomide in a case of metastatic primitive myxoid mesenchymal tumour of infancy by Yu, S. H., Kan, Amanda N. C., To, K. F., Lam, Y. L., Yan, Carol L. S., Liu, Anthony P. Y., Ku, Dennis T. L.

Get full text

Epidemiology and outcomes of pediatric transplant‐associated thrombotic microangiopathy in Hong Kong by Chan, Wilson Yau Ki, Ma, Alison Lap Tak, Chan, Eugene Yu Hin, Kan, Amanda Nim Chi, Ng, Wai Fu, Lee, Pamela Pui Wah, Cheuk, Daniel Ka Leung, Chiang, Alan Kwok Shing, Leung, Wing, Chan, Godfrey Chi Fung

“…Background Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an under‐recognized yet potentially devastating complication of hematopoietic stem cell…”
Get full text

Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling by Sun, Stella, Kiang, Karrie M Y, Ho, Amy S W, Lee, Derek, Poon, Ming-Wai, Xu, Fei-Fan, Pu, Jenny K S, Kan, Amanda N C, Lee, Nikki P Y, Liu, Xiao-Bing, Man, Kwan, Day, Philip J R, Lui, Wai-Man, Fung, Ching-Fai, Leung, Gilberto K K

“…Endoplasmic reticulum (ER) chaperone Prolyl 4-hydroxylase, beta polypeptide (P4HB) has previously been identified as a novel target for chemoresistance in…”
Get full text

Rare Pediatric Cerebellar High-Grade Gliomas Mimic Medulloblastomas Histologically and Transcriptomically and Show p53 Mutations by Shi, Zhi-Feng, Li, Kay Ka-Wai, Liu, Anthony Pak-Yin, Chung, Nellie Yuk-Fei, Chow, Chit, Chen, Hong, Kan, Nim-Chi Amanda, Zhu, Xian-Lun, Chan, Danny Tat-Ming, Mao, Ying, Ng, Ho-Keung

“…Pediatric high-grade gliomas (HGG) of the cerebellum are rare, and only a few cases have been documented in detail in the literature. A major differential…”
Get full text

Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome by Chan, Yat Chi, Kan, Amanda N. C., Yuen, Liz Y. P., Wan, Innes Y. P., Fung, Kevin K. F., Cheung, Yiu-fai, Leung, Karen K. Y., Ku, Dennis T. L., Liu, Anthony P. Y.

“…Low-grade fibromyxoid sarcomas (LGFMSs) are typically adult-onset tumors that arise from the extremities. Here, we report an exceptional case of primary…”
Get full text

Patterns of care and survival of Chinese glioblastoma patients in the temozolomide era: a Hong Kong population-level analysis over a 14-year period by Woo, Peter Y M, Yau, Stephen, Lam, Tai-Chung, Pu, Jenny K S, Li, Lai-Fung, Lui, Louisa C Y, Chan, Danny T M, Loong, Herbert H F, Lee, Michael W Y, Yeung, Rebecca, Kwok, Carol C H, Au, Siu-Kie, Tan, Tze-Ching, Kan, Amanda N C, Chan, Tony K T, Mak, Calvin H K, Mak, Henry K F, Ho, Jason M K, Cheung, Ka-Man, Tse, Teresa P K, Lau, Sarah S N, Chow, Joyce S W, El-Helali, Aya, Ng, Ho-Keung, Poon, Wai-Sang

“…The aim of this study is to address the paucity of epidemiological data regarding the characteristics, treatment patterns and survival outcomes of Chinese…”
Get full text

Pyrexia, Massive Hepatomegaly, and Extreme Hyperferritinemia by Kwok, Gerry, MB, BS, Kan, Amanda, MB, ChB, Leung, Rock Y.Y., MB, BS, Tam, Sidney, MB, BS, Lau, Chak-Sing, MD, Kwong, Yok-Lam, MD

Get full text

Dystroglycanopathy with two novel POMT1 mutations in a Chinese boy with developmental delay and muscular dystrophy by Chong, Yeow Kuan, Kwan Ma, Louis Che, Lo, Kit Lin, Lai Lee, Clary Ka, Mak, Chloe Miu, Chi Kan, Amanda Nim, Lam, Ching Wan

“…Abstract Alpha-dystroglycanopathies are a group of diseases due to reduced glycosylation of alpha-dystroglycan, which commonly result from mutations in POMT1 ,…”
Get full text

Implementation of Public Funded Genome Sequencing in Evaluation of Fetal Structural Anomalies by So, Po Lam, Hui, Annie Shuk Yi, Ma, Teresa Wei Ling, Shu, Wendy, Hui, Amelia Pui Wah, Kong, Choi Wah, Lo, Tsz Kin, Kan, Amanda Nim Chi, Kan, Elaine Yee Ling, Chong, Shuk Ching, Chung, Brian Hon Yin, Luk, Ho Ming, Choy, Kwong Wai, Kan, Anita Sik Yau, Leung, Wing Cheong

“…With the advancements in prenatal diagnostics, genome sequencing is now incorporated into clinical use to maximize the diagnostic yield following uninformative…”
Get full text

Clinical and pathological characterization of FLNC‐related myofibrillar myopathy caused by founder variant c.8129G>A in Hong Kong Chinese by Lee, Han‐Chih Hencher, Wong, Shun, Sheng, Bun, Pan, Nin‐Yuan Keith, Leung, Ying‐Kit Frank, Lau, Kwok‐Kwong Dominic, Cheng, Yue Sandy, Ho, Luen‐Cheung, Li, Richard, Lee, Chi‐Nam, Tsoi, Tak‐Hong, Cheung, Yuk‐Fai Nelson, Fu, Yat‐Pang Michael, Kan, Nim‐Chi Amanda, Chu, Yim‐Pui, Au, Wing‐Chi Lisa, Yeung, Hon‐Ming Jonas, Li, Siu‐Hung, Cheung, Chi‐Fung Mark, Tong, Hok‐Fung, Hung, Ling‐Yin Esther, Chan, Tina Yee‐Ching, Li, Chi Terence, Tong, Tsz‐Yan Tammy, Tong, Tin‐Wing Candy, Leung, Ho‐Ying Cory, Lee, Ka‐Ho, Yeung, Sung‐Yan Sue, Lee, Sau‐Yin Blanka, Lau, Tze‐Chin Gene, Lam, Ching‐Wan, Mak, Chloe Miu, Chan, Albert Yan‐Wo

“…FLNC‐related myofibrillar myopathy could manifest as autosomal dominant late‐onset slowly progressive proximal muscle weakness; involvements of cardiac and/or…”
Get full text

To do genomics or not do? This is the question by Ng, Ho-Keung, Chan, Aden, Kan, Nim-Chi Amanda, Ku, Dennis, Chan, Danny, Li, Kay

Get full text

HGG-37. A case ofETV6-NTRK3 fusion driven infantile hemispheric glioma (IHG) with acquired drug resistance against first- and second-generation NTRK-inhibitors by Ku, Dennis T L, Liu, Anthony P Y, Kan, Amanda N C, Yuen, Liz Y P, Shing, M K, Yan, Carol Y L, Fu, Eric, Yau, Jeffrey P W, Luk, C W, Ng, H K, Chan, Godfrey C F

“…A 3-month-old girl had left cerebral infantile hemispheric glioma (IHG), H3 wild type (wt), Grade IV (WHO2020) with diffuse leptomeningeal and spinal…”
Get full text

HGG-37. A case of ETV6-NTRK3 fusion driven infantile hemispheric glioma (IHG) with acquired drug resistance against first- and second-generation NTRK-inhibitors by Ku, Dennis T L, Liu, Anthony P Y, Kan, Amanda N C, Yuen, Liz Y P, Shing, M K, Yan, Carol Y L, Fu, Eric, Yau, Jeffrey P W, Luk, C W, Ng, H K, Chan, Godfrey C F

“…A 3-month-old girl had left cerebral infantile hemispheric glioma (IHG), H3 wild type (wt), Grade IV (WHO2020) with diffuse leptomeningeal and spinal…”
Get full text

PATH-10. Nanopore sequencing reveals novel ALK fusion with interposed element in a neonate with hemispheric glioma by Liu, Anthony P Y, Chan, Chris T L, Ma, Edmond S K, Ho, Wilson W S, Ku, Dennis T L, Shing, Matthew M K, Kan, Amanda N C, Chan, Godfrey C F, Ng, Ho-Keung

“…Here we describe the clinical course and unique molecular findings in a female neonate with infantile hemispheric glioma (IHG). The patient presented at the…”
Get full text

Bleeding duodenal choriocarcinoma: An unusual cause of positive urine pregnancy test by Li, Jimmy Chak‐Man, Kan, Amanda Nim‐Chi, Wan, Suk‐King, Chan, Angus Chi‐Wai

“…Primary choriocarcinoma of the duodenum is exceedingly rare. Only a few cases have been reported previously. A case of extragenital choriocarcinoma of the…”
Get full text

OMIC-07. FEASIBILITY AND UTILITY OF EPIGENOMIC PROFILING FOR CHILDHOOD CNS TUMORS IN HONG KONG by P.Y. Liu, Anthony, Ho, Ronnie S L, Li, Kay K W, Chan, Shing, Ku, Dennis T L, Fu, Eric, Luk, Chung-Wing, Yau, Jeffrey P W, Ling, Siu-Cheung, Chung, Brian H Y, Yang, Wanling, Kan, Amanda, Shing, Matthew M K, Ng, Ho-Keung, Chan, Godfrey C F

“…Genome-wide DNA methylation profiling has emerged as an important diagnostic tool that complements histopathology for CNS tumors in children and adults…”
Get full text

Cytoplasmic body pathology in severe ACTA1 -related myopathy in the absence of typical nemaline rods by Donkervoort, Sandra, Chan, Sophelia HS, Hotchkiss, Leslie, Bradley, Nathaniel, Nguyen, David, Leach, Meganne E, Mohassel, Payam, Hu, Ying, Thangarajh, Mathula, Bharucha-Goebel, Diana, Kan, Amanda, Ho, Ronnie SL, Reyes, Christine, Nance, Jessica, Moore, Steven A, Foley, A. Reghan, Bönnemann, Carsten G

“…Highlights • ACTA1 -myopathy can present with cytoplasmic bodies in the absence of nemaline rods. • p.Asn94Lys ACTA1 mutation may be linked to this pathology…”
Get full text

A sarcoma of 23 years' duration: symptom duration is not a reliable parameter to exclude malignancy by Lam, Y L, Ho, W Y, Ng, T P, Kan, Amanda, Shek, Tony W H

“…This report describes a 31-year-old woman with a 23-year history of a right buttock mass that was otherwise asymptomatic, but was proven to be a low-grade…”
Get full text

Durable disease control with apatinib, irinotecan and temozolomide in a case of metastatic primitive myxoid mesenchymal tumour of infancy by Yu, S H, Kan, Amanda N C, To, K F, Lam, Y L, Yan, Carol L S, Liu, Anthony P Y, Ku, Dennis T L

Get full text