Search Results - "Kamuhabwa, Appolinary A"

Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in Southeast of Tanzania by Bwire, George M., Ngasala, Billy, Mikomangwa, Wigilya P., Kilonzi, Manase, Kamuhabwa, Appolinary A. R.

“…In Tanzania, chloroquine was replaced by sulphadoxine- pyrimethamine (SP) as a first-line for treatment of uncomplicated malaria. Due to high resistance in…”
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Prevalence and correlates of intestinal schistosomiasis infection among school-aged children in North-Western Tanzania by Mnkugwe, Rajabu Hussein, Minzi, Omary S, Kinung'hi, Safari M, Kamuhabwa, Appolinary A, Aklillu, Eleni

“…Schistosomiasis is a neglected tropical disease that continues to cause morbidity and mortality in Sub Saharan Africa. Due to its endemicity, co-infection with…”
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Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio by Mlugu, Eulambius M, Minzi, Omary M, Kamuhabwa, Appolinary A R, Diczfalusy, Ulf, Aklillu, Eleni

“…Changes in cortisol and other hormones during pregnancy may alter CYP3A enzymes activity, but data from sub-Saharan Africa are sparse. We investigated the…”
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Optimal single sampling time-point for monitoring of praziquantel exposure in children by Mnkugwe, Rajabu Hussein, Ngaimisi Kitabi, Eliford, Kinung’hi, Safari, Kamuhabwa, Appolinary A. R., Minzi, Omary Mashiku, Aklillu, Eleni

“…Praziquantel pharmacokinetics studies in schistosomiasis infected children are scarce partly due to the challenges/complexity of intensive blood sampling in…”
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Diagnostic performance of CareStart™ malaria HRP2/pLDH test in comparison with standard microscopy for detection of uncomplicated malaria infection among symptomatic patients, Eastern Coast of Tanzania by Bwire, George M, Ngasala, Billy, Kilonzi, Manase, Mikomangwa, Wigilya P, Felician, Fatuma F, Kamuhabwa, Appolinary A R

“…CareStart™ malaria HRP2/pLDH (Pf/pan) combo test is one of the several rapid diagnostic tests (RDT) approved for diagnosis of malaria at the point of care in…”
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Effect of sulfadoxine-pyrimethamine doses for prevention of malaria during pregnancy in hypoendemic area in Tanzania by Mikomangwa, Wigilya P, Minzi, Omary, Mutagonda, Ritah, Baraka, Vito, Mlugu, Eulambius M, Aklillu, Eleni, Kamuhabwa, Appolinary A R

“…Malaria in pregnancy increases the risk of deleterious maternal and birth outcomes. The use of ≥ 3 doses of sulfadoxine-pyrimethamine (SP) for intermittent…”
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Pharmacokinetics of piperaquine and its association with intermittent malaria preventive therapy outcomes during pregnancy by Mlugu, Eulambius M, Minzi, Omary M S, Johansson, Mats, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Dihydroartemisinin-piperaquine (DHP) recently showed superior effectiveness over sulfadoxine-pyrimethamine for malaria intermittent preventive treatment in…”
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Adverse birth outcomes among mothers who received intermittent preventive treatment with Sulphadoxine-Pyrimethamine in the low malaria transmission region by Mikomangwa, Wigilya P, Oms, Minzi, Aklillu, Eleni, Kamuhabwa, Appolinary A R

“…Malaria in pregnancy increases the risk of adverse birth outcomes such as low birth weight (LBW), maternal and foetal anemia. In Tanzania, some areas have…”
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Establishment of clinical pharmacy services: evidence-based information from stakeholders by Kilonzi, Manase, Mutagonda, Ritah F, Mwakawanga, Dorkasi L, Mlyuka, Hamu J, Mikomangwa, Wigilya P, Kibanga, Wema A, Marealle, Alphonce Ignace, Mallya, Bertha, Katabalo, Deogratias, Sanga, Sofia, Kalokola, Fredrick, Rwegasha, John, Magambo, Rose, Mmassy, John, Kabissi, Sungwa, Balati, Josephine A, Maduki, Peter, Minzi, Omary Mashiku, Kamuhabwa, Appolinary A R

“…High morbidity and mortality related to the use of drugs resulted in demand for clinical pharmacy services (CPS) globally. In developed countries, the…”
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Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women by Mutagonda, Ritah F, Kamuhabwa, Appolinary A R, Minzi, Omary M S, Massawe, Siriel N, Asghar, Muhammad, Homann, Manijeh V, Färnert, Anna, Aklillu, Eleni

“…Pregnancy has considerable effects on the pharmacokinetic properties of drugs used to treat uncomplicated Plasmodium falciparum malaria. The role of…”
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Efficacy of ivermectin and albendazole combination in suppressing transmission of lymphatic filariasis following mass administration in Tanzania: a prospective cohort study by Fimbo, Adam M, Mnkugwe, Rajabu Hussein, Mlugu, Eulambius Mathias, Kunambi, Peter P, Malishee, Alpha, Minzi, Omary M S, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Preventive chemotherapy with ivermectin and albendazole (IA) in mass drug administration (MDA) programs for all at-risk populations is the core public health…”
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Adherence, Effectiveness and Safety of Dolutegravir Based Antiretroviral Regimens among HIV Infected Children and Adolescents in Tanzania by Mutagonda, Ritah F., Mlyuka, Hamu J., Maganda, Betty A., Kamuhabwa, Appolinary A. R.

“…Objectives:This study aimed at assessing adherence, effectiveness, and safety of DTG-based HAART regimens among HIV-infected children and adolescents in…”
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Barriers and Facilitators of Availability of Hydroxyurea for Sickle Cell Disease in Tanzania; A Qualitative Study of Pharmaceutical Manufacturers, Importers, and Regulators by Mlyuka, Hamu J, Kilonzi, Manase, Mutagonda, Ritah F, Chirande, Lulu, Mikomangwa, Wigilya P, Myemba, David T, Sambayi, Godfrey, Mwakawanga, Dorkasi L, Ndunguru, Joyce, Jonathan, Agnes, Makani, Julie, Ruggajo, Paschal, Minja, Irene K, Balandya, Emmanuel, Kamuhabwa, Appolinary A R

“…Despite three decades of proven safety and effectiveness of hydroxyurea in modifying sickle cell disease (SCD), its accessibility is limited in Sub-Saharan…”
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Safety and Tolerability of Ivermectin and Albendazole Mass Drug Administration in Lymphatic Filariasis Endemic Communities of Tanzania: A Cohort Event Monitoring Study by Fimbo, Adam M, Minzi, Omary Mashiku, Mmbando, Bruno P, Gurumurthy, Parthasarathi, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Ivermectin and albendazole (IA) combination preventive chemotherapy to all at-risk populations is deployed to eliminate lymphatic filariasis. Although safety…”
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Malaria prevalence, severity and treatment outcome in relation to day 7 lumefantrine plasma concentration in pregnant women by Mutagonda, Ritah F, Kamuhabwa, Appolinary A R, Minzi, Omary M S, Massawe, Siriel N, Maganda, Betty A, Aklillu, Eleni

“…Day 7 plasma concentrations of lumefantrine (LF) can serve as a marker to predict malaria treatment outcome in different study populations. Two main cut-off…”
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Prevalence and Correlates of Asymptomatic Malaria and Anemia on First Antenatal Care Visit among Pregnant Women in Southeast, Tanzania by Mlugu, Eulambius M, Minzi, Omary, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Asymptomatic malaria and anemia during pregnancy increase the risk of negative birth outcomes. This cross-sectional study investigated the prevalence and…”
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Pregnancy and CYP3A5 Genotype Affect Day 7 Plasma Lumefantrine Concentrations by Mutagonda, Ritah F, Minzi, Omary M S, Massawe, Siriel N, Asghar, Muhammad, Färnert, Anna, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Pregnancy and pharmacogenetics variation alter drug disposition and treatment outcome. The objective of this study was to investigate the effect of pregnancy…”
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Barriers and facilitators of integration of pharmacists in the provision of clinical pharmacy services in Tanzania by Kilonzi, Manase, Mutagonda, Ritah F, Mlyuka, Hamu J, Mwakawanga, Dorkasi L, Mikomangwa, Wigilya P, Kibanga, Wema A, Marealle, Alphonce Ignace, Mallya, Bertha, Katabalo, Deogratias, Sanga, Sofia, Kalokola, Fredrick, Rwegasha, John, Magambo, Rose, Mmassy, John, Kabissi, Sungwa, Balati, Josephine A, Maduki, Peter, OmaryMashikuMinzi, Kamuhabwa, Appolinary A R

“…Collaboration between medical doctors and nurses in the provision of healthcare services has been there for decades. The concept of clinical pharmacy services…”
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Efficacy and Safety of Praziquantel for Treatment of Schistosoma mansoni Infection among School Children in Tanzania by Mnkugwe, Rajabu Hussein, Minzi, Omary S, Kinung'hi, Safari M, Kamuhabwa, Appolinary A, Aklillu, Eleni

“…Single-dose targeted praziquantel preventive chemotherapy is the WHO-recommended intervention for schistosomiasis control in endemic countries. The objective…”
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HIV pre-exposure prophylaxis use during periods of unprotected sex among female sex workers in Tanga city, Tanzania: a control arm analysis of the pragmatic quasi-experimental trial by Mikomangwa, Wigilya P, Moen, Kåre, Mmbaga, Elia J, Metta, Emmy, Kibusi, Stephen M, Leshabari, Melkizedeck T, Kamuhabwa, Appolinary A R, Kwesigabo, Gideon

“…Pre-exposure prophylaxis (PrEP) prevention-effective adherence is of critical importance but challenging particularly among key populations where periods of…”
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