Search Results - "Kamrud, K I"
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Alphavirus replicon particle vaccines developed for use in humans induce high levels of antibodies to influenza virus hemagglutinin in swine: Proof of concept
Published in Vaccine (08-01-2010)“…Abstract A propagation-defective, single-cycle, alphavirus replicon particle (RP) system was used to produce two vaccines against human influenza virus…”
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Haemagglutinin and nucleoprotein replicon particle vaccination of swine protects against the pandemic H1N1 2009 virus
Published in Veterinary record (12-10-2013)“…The recent emergence of the pandemic H1N1 (pH1N1) and H3N2 variant influenza A viruses (IAV) in 2009 and 2011–2012, respectively, highlight the zoonotic…”
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Development and characterization of promoterless helper RNAs for the production of alphavirus replicon particle
Published in Journal of general virology (01-07-2010)“…Alphavirus-based replicon systems are frequently used as preclinical vectors and as antigen discovery tools, and they have recently been assessed in clinical…”
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Genetically engineered resistance to dengue-2 virus transmission in mosquitoes
Published in Science (American Association for the Advancement of Science) (10-05-1996)“…The control of arthropod-borne virus diseases such as dengue may ultimately require the genetic manipulation of mosquito vectors to disrupt virus transmission…”
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Alphavirus replicon approach to promoterless analysis of IRES elements
Published in Virology (New York, N.Y.) (10-04-2007)“…Abstract Here we describe a system for promoterless analysis of putative internal ribosome entry site (IRES) elements using an alphavirus (family Togaviridae )…”
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DNA Vaccination with Hantavirus M Segment Elicits Neutralizing Antibodies and Protects against Seoul Virus Infection
Published in Virology (New York, N.Y.) (15-03-1999)“…Seoul virus (SEOV) is one of four known hantaviruses causing hemorrhagic fever with renal syndrome (HFRS). Candidate naked DNA vaccines for HFRS were…”
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Comparison of the Protective Efficacy of Naked DNA, DNA-based Sindbis Replicon, and Packaged Sindbis Replicon Vectors Expressing Hantavirus Structural Genes in Hamsters
Published in Virology (New York, N.Y.) (10-10-1999)“…Seoul virus (SEOV) is a member of the Hantavirus genus (family Bunyaviridae) and an etiological agent of hemorrhagic fever with renal syndrome. The medium (M)…”
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Molecularly engineered resistance to California serogroup virus replication in mosquito cells and mosquitoes
Published in Proceedings of the National Academy of Sciences - PNAS (30-04-1996)“…Introduction of genetic elements derived from a viral pathogen's genome may be used to reduce the vectorial capacity of mosquitoes for that virus. A double…”
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Green fluorescent protein expressed in living mosquitoes--without the requirement of transformation
Published in BioTechniques (01-10-1996)“…Mosquitoes transmit viruses, protozoa and nematodes that are major causes of morbidity and mortality in humans. Details of arthropod anatomy and development,…”
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Use of the Sindbis replicon system for expression of LaCrosse virus envelope proteins in mosquito cells
Published in Archives of virology (01-01-1998)“…The Sindbis replicon expression system was used to express La Crosse (LAC) virus envelope glycoprotein genes in both mammalian and mosquito cell culture…”
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Expression strategy of the M genome segment of Hantaan virus
Published in Virus research (01-01-1994)“…The medium (M) genome segment of Hantaan virus encodes the envelope glycoproteins, G1 and G2, in a continuous open reading frame with a gene order of…”
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Detection of expressed chloramphenicol acetyltransferase in the saliva of Culex pipiens mosquitoes
Published in Insect biochemistry and molecular biology (01-05-1997)“…Mosquito salivary glands play an important role in the transmission of arthropod-borne pathogens. The ability to express genes in mosquitoes would be a…”
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Replication and expression of a recombinant Sindbis virus in mosquitoes
Published in Insect molecular biology (01-11-1995)“…A recombinant Sindbis virus, TE/3'2J/ANTI-S, containing LaCrosse virus small segment cDNA in antisense orientation, was inoculated into Aedes triseriatus…”
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The Expression of Chloramphenicol Acetyltransferase in Mosquitoes and Mosquito Cells Using a Packaged Sindbis Replicon System
Published in Experimental parasitology (01-11-1995)“…Sindbis (SIN) replicon virus was used to express chloramphenicol acetyltransferase (CAT) in Aedes albopictus (C6/36) cells and Aedes triseriatus mosquitoes…”
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Alphavirus Replicon Particles Are Highly Immunogenic in the Murine Malaria Model by Homologous or Heterologous Immunization
Published in The open vaccine journal (13-10-2008)“…We evaluated the immunogenicity of virus-like replicon particles (VRP) derived from an attenuated strain of the alphavirus Venezuelan equine encephalitis…”
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Murine leukemia virus pseudotypes of La Crosse and Hantaan Bunyaviruses: a system for analysis of cell tropism
Published in Virus research (01-10-1999)“…We have developed a system for the preparation of La Crosse virus (LAC) and Hantaan virus (HTN) pseudotypes using a murine leukemia virus vector. After…”
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Alphavirus vectors and vaccination
Published in Reviews in medical virology (01-09-2002)“…Alphaviruses are positive‐stranded RNA viruses that have a broad host range and therefore are capable of replicating in many vertebrate and invertebrate cells…”
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Restricted and selective tropism of a Venezuelan equine encephalitis virus-derived replicon vector for human dendritic cells
Published in Viral Immunology (01-03-2007)“…Dendritic cells (DCs) consist of heterogeneous phenotypic populations and have diverse immunostimulatory functions dependent on both lineage and functional…”
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Venezuelan equine encephalitis replicon immunization overcomes intrinsic tolerance and elicits effective anti-tumor immunity to the 'self' tumor-associated antigen, Neu in a rat mammary tumor model
Published in Breast cancer research and treatment (01-12-2003)“…Many tumor-associated antigens (TAAs) represent 'self' antigens and as such, are subject to the constraints of immunologic tolerance. There are significant…”
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