Search Results - "Kampman, K. M."

Case–control association analysis of polymorphisms in the delta-opioid receptor, OPRD1 , with cocaine and opioid addicted populations by Crist, R.C, Ambrose-Lanci, L.M, Vaswani, M, Clarke, T.K, Zeng, A, Yuan, C, Ferraro, T.N, Hakonarson, H, Kampman, K.M, Dackis, C.A, Pettinati, H.M, O’Brien, C.P, Oslin, D.W, Doyle, G.A, Lohoff, F.W, Berrettini, W.H

“…Abstract Background Addiction susceptibility and treatment responsiveness are greatly influenced by genetic factors. Sequence variation in genes involved in…”
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Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction by Clarke, T.‐K., Ambrose‐Lanci, L., Ferraro, T. N., Berrettini, W. H., Kampman, K. M., Dackis, C. A., Pettinati, H. M., O’Brien, C. P., Oslin, D. W., Lohoff, F. W.

“…Genetic factors are believed to account for 30–50% of the risk for cocaine and heroin addiction. Dynorphin peptides, derived from the prodynorphin (PDYN)…”
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The role of baseline insomnia in moderating the hypnotic properties of quetiapine by Krouse, R.A., Morales, K.H., Kampman, K.M., Chakravorty, S.

“…•Alcohol craving was positively associated with insomnia.•Quetiapine improved sleep in those with insomnia at baseline relative to placebo.•This improvement in…”
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Reliability and validity of the cocaine selective severity assessment by Kampman, Kyle M., Volpicelli, Joseph R., Mcginnis, David E., Alterman, Arthur I., Weinrieb, Robert M., D’Angelo, Lisa, Epperson, Louise E.

“…This article assesses the reliability and validity of the Cocaine Selective Severity Assessment (CSSA), a measure of cocaine abstinence signs and symptoms…”
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A delta-opioid receptor genetic variant is associated with abstinence prior to and during cocaine dependence treatment by Crist, R.C, Doyle, G.A, Kampman, K.M, Berrettini, W.H

“…Highlights • Cocaine dependent African-Americans were randomized to topiramate or placebo. • Cocaine use in both groups was associated with rs678849, an OPRD1…”
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Cocaine Withdrawal Symptoms and Initial Urine Toxicology Results Predict Treatment Attrition in Outpatient Cocaine Dependence Treatment by Kampman, Kyle M, Alterman, Arthur I, Volpicelli, Joseph R, Maany, Iradj, Muller, Eric S, Luce, Douglas D, Mulholland, Ellen M, Jawad, Abbas F, Parikh, Gargi A, Mulvaney, Frank D, Weinrieb, Robert M, O'Brien, Charles P

“…This study evaluated the ability of cocaine withdrawal symptoms, measured by the Cocaine Selective Severity Assessment (CSSA) and initial urine toxicology…”
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Amantadine in the Treatment of Cocaine-Dependent Patients With Severe Withdrawal Symptoms by Kampman, Kyle M., Volpicelli, Joseph R., Alterman, Arthur I., Cornish, James, O'Brien, Charles P.

“…OBJECTIVE: The study examined the effectiveness of amantadine in reducing cocaine withdrawal symptoms and improving treatment outcome among cocaine-dependent…”
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The Effects of Naltrexone on Alcohol and Cocaine Use in Dually Addicted Patients by Oslin, David W, Pettinati, Helen M, Volpicelli, Joseph R, Wolf, Alexia L, Kampman, Kyle M, O’Brien, Charles P

“…Concurrent dependence on cocaine and alcohol is common among patients seeking addiction treatment. This study was undertaken to explore the effectiveness of…”
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Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study by Dackis, Charles A, Lynch, Kevin G, Yu, Elmer, Samaha, Frederick F, Kampman, Kyle M, Cornish, James W, Rowan, Amy, Poole, Sabrina, White, Lenae, O'Brien, Charles P

“…Modafinil is a novel compound that is approved for the treatment of narcolepsy. It is now being studied as a potential treatment for cocaine dependence…”
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Tolerance and Sensitization to the Effects of Cocaine Use in Humans: A Retrospective Study of Long-Term Cocaine Users in Philadelphia by Small, A. C., Kampman, K. M., Plebani, J., De Jesus Quinn, M., Peoples, L., Lynch, K. G.

“…In the effort to develop medications to combat addiction, researchers have developed models that attempt to describe the neurobiological process of cocaine…”
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Open trials as a method of prioritizing medications for inclusion in controlled trials for cocaine dependence by Kampman, Kyle M, Rukstalis, Margaret, Ehrman, Ronald, Mcginnis, David E, Gariti, Peter, Volpicelli, Joseph R, Pettinati, Helen, O’Brien, Charles P

“…This paper describes a rapid and systematic method of using open trials to identify medications that may be useful for the treatment of cocaine dependence…”
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Effectiveness of propranolol for cocaine dependence treatment may depend on cocaine withdrawal symptom severity by Kampman, Kyle M., Volpicelli, Joseph R., Mulvaney, Frank, Alterman, Arthur I., Cornish, James, Gariti, Peter, Cnaan, Avital, Poole, Sabrina, Muller, Eric, Acosta, Thalia, Luce, Douglas, O'Brien, Charles

“…Propranolol may reduce symptoms of autonomic arousal associated with early cocaine abstinence and improve treatment outcome. This trial was an 8-week,…”
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The combination of phentermine and fenfluramine reduced cocaine withdrawal symptoms in an open trial by Kampman, Kyle M, Rukstalis, Margaret, Pettinati, Helen, Muller, Eric, Acosta, Thalia, Gariti, Peter, Ehrman, Ron, O'Brien, Charles P

“…Kampman et al report on the results of an open-label pilot of phen/fen for cocaine dependence. The trial was completed prior to reports of valvular heart…”
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Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial by Lofwall, Michelle R, Walsh, Sharon L, Nunes, Edward V, Bailey, Genie L, Sigmon, Stacey C, Kampman, Kyle M, Frost, Michael, Tiberg, Fredrik, Linden, Margareta, Sheldon, Behshad, Oosman, Sonia, Peterson, Stefan, Chen, Michael, Kim, Sonnie

“…Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations. To determine whether treatment involving novel weekly and…”
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Buprenorphine Implants for Treatment of Opioid Dependence: A Randomized Controlled Trial by Ling, Walter, Casadonte, Paul, Bigelow, George, Kampman, Kyle M, Patkar, Ashwin, Bailey, Genie L, Rosenthal, Richard N, Beebe, Katherine L

“…CONTEXT Limitations of existing pharmacological treatments for opioid dependence include low adherence, medication diversion, and emergence of withdrawal…”
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Combination of the dopaminergic agent, phentermine, and the serotonergic agent, fenfluramine, in the treatment of cocaine dependence by Kampman, K M, Volpicelli, J

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Sustained brain response to repeated drug cues is associated with poor drug‐use outcomes by Regier, Paul S., Jagannathan, Kanchana, Franklin, Teresa R., Wetherill, Reagan R., Langleben, Daniel D., Gawyrsiak, Michael, Kampman, Kyle M., Childress, Anna Rose

“…A threefold increase in fatal cocaine overdoses during the past decade highlights the critical lack of medications for cocaine use disorders. The brain…”
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What’s New in the Treatment of Cocaine Addiction? by Kampman, Kyle M.

“…Cocaine dependence continues to be a significant public health problem in the United States. The number of regular cocaine users has not declined significantly…”
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A Double-Blind, Placebo-Controlled Trial of Modafinil for Cocaine Dependence by DACKIS, Charles A, KAMPMAN, Kyle M, LYNCH, Kevin G, PETTINATI, Helen M, O'BRIEN, Charles P

“…Despite years of active research, there are still no approved medications for the treatment of cocaine dependence. Modafinil is a glutamate-enhancing agent…”
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A pilot trial of topiramate for the treatment of cocaine dependence by Kampman, Kyle M, Pettinati, Helen, Lynch, Kevin G, Dackis, Charles, Sparkman, Thorne, Weigley, Catherine, O’Brien, Charles P

“…Background: Both GABAergic and glutamatergic neurons appear to be important modulators of the brain reward system and medications that affect GABA and…”
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