Search Results - "Kamoun, W S"
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In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model
Published in Neuro-oncology (Charlottesville, Va.) (01-04-2010)“…The vessel caliber index (VCI), a magnetic resonance imaging biomarker of the average blood vessel diameter, is increasingly being used as a tool for assessing…”
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Liver Microcirculation Analysis by Red Blood Cell Motion Modeling in Intravital Microscopy Images
Published in IEEE transactions on biomedical engineering (01-01-2008)“…Intravital microscopy has been used to visualize the microcirculation by imaging fluorescent labeled red blood cells (RBCs). Traditionally, microcirculation…”
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Chronic Alcohol Consumption Upregulates Caveolin-1 and Sensitizes the Liver Microcirculation to Endotoxin: 192
Published in Shock (Augusta, Ga.) (01-06-2004)Get full text
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LPS inhibits endothelin-1-induced endothelial NOS activation in hepatic sinusoidal cells through a negative feedback involving caveolin-1
Published in Hepatology (Baltimore, Md.) (2006)“…During endotoxemia, liver microcirculation disruption is characterized by a hypersensitivity to the constrictor effects of endothelin 1 (ET-1). The shift of…”
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Oxidative stress disrupts nitric oxide synthase activation in liver endothelial cells
Published in Free radical biology & medicine (15-11-2005)“…Oxidative stress may mediate vascular disruption associated with a loss of endothelial nitric oxide synthase (eNOS) activity and a hypersensitivity to the…”
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Chronic ethanol sensitizes the liver to endotoxin via effects on endothelial nitric oxide synthase regulation
Published in Shock (Augusta, Ga.) (01-11-2005)“…In vivo studies have shown that chronic alcohol consumption sensitizes the liver to endotoxemic shock, leading to liver microcirculation disruption. In the…”
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Segmentation of vasculature for intravital microscopy using bridging vessel snake
Published in 2006 3rd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, WA, 6-9 April 2006 (2006)“…Robustly segmenting vessels even with less sharp boundary is important for achieving accurate biological analysis of blood vessels regulation within organs…”
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Conference Proceeding Journal Article -
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Induction of biphasic changes in perfusion heterogeneity of rat liver after sequential stress in vivo
Published in Shock (Augusta, Ga.) (01-10-2005)“…Trauma and subsequent sepsis lead to hepatic microcirculation disruption through various molecular mechanisms in which endothelin-1 (ET-1) plays a pivotal…”
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Quantification of hepatic microcirculation heterogeneity of perfusion: Effects of endothelin-1
Published in Microvascular research (01-05-2005)“…Stress alters hepatic perfusion heterogeneously leading to mismatch of oxygen supply and demand. Endothelin-1 (ET-1) has been linked to stress-mediated…”
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